某醫(yī)院新生兒重癥監(jiān)護(hù)病房患者感染病原菌種類變遷
發(fā)布時(shí)間：2018-07-13 11:11
【摘要】：目的研究NICU患者感染病原菌種類的變遷及其耐藥情況。方法通過回顧性調(diào)查方法,對(duì)某醫(yī)院NICU住院患者連續(xù)6年醫(yī)院感染病原菌種類變化情況及其耐藥性進(jìn)行了調(diào)查。結(jié)果該醫(yī)院NICU患者連續(xù)6年共送檢病原學(xué)標(biāo)本10 971份,分離出病原菌1 876株,陽(yáng)性率17.10%。其中革蘭陰性菌占67.86%,革蘭陽(yáng)性菌占26.44%,真菌占5.70%。連續(xù)6年中,臨床標(biāo)本分離的革蘭陰性菌呈現(xiàn)下降趨勢(shì),而革蘭陽(yáng)性菌和真菌分離率則出現(xiàn)上升趨勢(shì)。革蘭陰性菌優(yōu)勢(shì)菌為肺炎克雷伯菌和大腸埃希菌,革蘭陽(yáng)性菌優(yōu)勢(shì)菌為葡萄球菌和B族鏈球菌。臨床分離的革蘭陰性菌對(duì)頭孢類抗菌藥物耐藥率較高,保持對(duì)碳青霉烯類抗菌藥物敏感。結(jié)論 NICU患者醫(yī)院感染病原菌仍以革蘭陰性菌為主,但革蘭陽(yáng)性球菌和真菌分離率呈現(xiàn)上升趨勢(shì)。
[Abstract]:Objective to study the variation and drug resistance of pathogenic bacteria in NICU patients. Methods A retrospective investigation was conducted to investigate the variation and drug resistance of nosocomial infection pathogens in NICU patients for 6 consecutive years. Results A total of 10 971 pathogenic specimens were collected from NICU patients in this hospital for 6 consecutive years. 1 876 strains of pathogens were isolated and the positive rate was 17. 10%. Gram-negative bacteria accounted for 67.86%, Gram-positive bacteria 26.44% and fungi 5.70%. In the past 6 years, the Gram-negative bacteria isolated from clinical specimens showed a decreasing trend, while the rates of Gram-positive bacteria and fungi increased. The dominant bacteria of Gram-negative bacteria were Klebsiella pneumoniae and Escherichia coli, and the dominant bacteria of Gram-positive bacteria were Staphylococcus and Group B Streptococcus. The clinical isolates of Gram-negative bacteria showed high resistance to cephalosporins and remained sensitive to carbapenes. Conclusion Gram-negative bacteria are the main pathogens of nosocomial infection in NICU patients, but the isolation rate of Gram-positive cocci and fungi is increasing.
【作者單位】： 溫州市兒童醫(yī)院;
【分類號(hào)】：R197.32;R722.13
本文編號(hào)：2119155
[Abstract]:Objective to study the variation and drug resistance of pathogenic bacteria in NICU patients. Methods A retrospective investigation was conducted to investigate the variation and drug resistance of nosocomial infection pathogens in NICU patients for 6 consecutive years. Results A total of 10 971 pathogenic specimens were collected from NICU patients in this hospital for 6 consecutive years. 1 876 strains of pathogens were isolated and the positive rate was 17. 10%. Gram-negative bacteria accounted for 67.86%, Gram-positive bacteria 26.44% and fungi 5.70%. In the past 6 years, the Gram-negative bacteria isolated from clinical specimens showed a decreasing trend, while the rates of Gram-positive bacteria and fungi increased. The dominant bacteria of Gram-negative bacteria were Klebsiella pneumoniae and Escherichia coli, and the dominant bacteria of Gram-positive bacteria were Staphylococcus and Group B Streptococcus. The clinical isolates of Gram-negative bacteria showed high resistance to cephalosporins and remained sensitive to carbapenes. Conclusion Gram-negative bacteria are the main pathogens of nosocomial infection in NICU patients, but the isolation rate of Gram-positive cocci and fungi is increasing.
【作者單位】： 溫州市兒童醫(yī)院;
【分類號(hào)】：R197.32;R722.13
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