本文選題：肺炎 + 支原體��； 參考：《中國全科醫(yī)學(xué)》2017年S1期

【摘要】：目的探討兒童重癥肺炎支原體肺炎(SMPP)紅細(xì)胞分布寬度(RDW)與心肌損害的相關(guān)性分析。方法選取瑞安市人民醫(yī)院2013—2017年收治的142例SMPP患兒為研究對(duì)象,按照住院期間是否發(fā)生心肌損害分為心肌損害組(n=40)和非心肌損害組(n=102),收集兩組一般臨床資料及實(shí)驗(yàn)室檢查指標(biāo),利用Logistic回歸方程分析RDW與SMPP患兒發(fā)生心肌損害的關(guān)系。結(jié)果心肌損害組發(fā)熱持續(xù)時(shí)間≥7 d、應(yīng)用大環(huán)內(nèi)酯類藥物時(shí)間≥7 d、糖皮質(zhì)激素應(yīng)用起始時(shí)間≥7 d、肺炎支原體(MP)抗體滴度≥1∶80、血清肌酸激酶同工酶(CK-MB)、肌鈣蛋白I(cTnI)、N-末端腦鈉肽前體(NT-pro BNP)、C反應(yīng)蛋白(CRP)水平高于與非心肌損害組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);心肌損害組RDW[(15.91±1.14)%]水平高于非心肌損害組[(14.75±1.17)%](t=5.352,P0.05);RDW增高患者中CK-MB、cTnI、NT-pro BNP、CRP水平高于RDW正�；颊�,差異有統(tǒng)計(jì)學(xué)意義(P0.05);RDW增高患者中心肌損害發(fā)生率(42.3%)高于RDW正常患者(20.0%),差異有統(tǒng)計(jì)學(xué)意義(χ~2=5.145,P0.05);Pearson相關(guān)分析顯示,RDW水平與CK-MB、cTnI、NT-pro BNP、CRP水平呈正相關(guān)(P0.05);多因素Logistic回歸分析顯示:RDW是SMPP患兒發(fā)生心肌損害的獨(dú)立危險(xiǎn)因素[OR=1.243,95%CI(1.136,1.551),P0.05]。結(jié)論機(jī)體高水平RDW可能是SMPP患兒發(fā)生心肌損害的獨(dú)立預(yù)測因素,臨床檢測RDW水平對(duì)評(píng)估此類患兒病情及預(yù)后具有一定的臨床意義。
[Abstract]:Objective to investigate the correlation between erythrocyte distribution width (RDW) and myocardial damage in children with severe mycoplasma pneumoniae pneumonia (SMPP). Methods 142 children with SMPP admitted in Ruian people's Hospital from 2013 to 2017 were selected as subjects. Myocardial damage was divided into two groups according to whether myocardial damage occurred during hospitalization. The general clinical data and laboratory parameters were collected, and the relationship between RDW and SMPP was analyzed by Logistic regression equation. Results in the myocardial injury group, the duration of fever was more than 7 days, the administration time of macrolides 鈮，

本文編號(hào)：2108967