發(fā)布時(shí)間：2018-06-28 22:03

  本文選題：丹參注射液 + 系膜增生性腎炎　； 參考：《中成藥》2017年08期

【摘要】：目的觀察丹參注射液治療小兒系膜增生性腎炎(MsPGN)的臨床應(yīng)用效果。方法對(duì)102例腎活檢確診的MsPGN患兒的臨床資料進(jìn)行回顧性研究,采用隨機(jī)數(shù)字表法分為觀察組和對(duì)照組各51例。對(duì)照組口服醋酸潑尼松片;觀察組給予醋酸潑尼松片的同時(shí)靜脈滴注丹參注射液。檢測各組MsPGN患兒治療前后的24 h尿蛋白定量(24h TP)、尿紅細(xì)胞(UM-RBC)數(shù)、血清腫瘤壞死因子-α(TNF-α)、Ⅳ型膠原(IV-C)水平的變化,并分析臨床療效。結(jié)果與對(duì)照組相比,觀察組患兒的24h TP、UM-RBC計(jì)數(shù)及血清TNF-α和IV-C水平均明顯下降(P0.05);觀察組的總有效率(88.23%),明顯高于對(duì)照組(76.47%),兩組間差異顯著(P0.05)。結(jié)論在常規(guī)西藥治療基礎(chǔ)上加用丹參注射液可提高M(jìn)sPGN患兒的臨床療效。
[Abstract]:Objective to observe the clinical effect of salvia miltiorrhiza injection on Mesangial proliferative glomerulonephritis (MsPGN) in children. Methods the clinical data of 102 children with MsPGN confirmed by renal biopsy were retrospectively studied. The patients were randomly divided into two groups: observation group (n = 51) and control group (n = 51). The control group was given prednisone acetate tablets and the observation group was treated with prednisone acetate tablets and Danshen injection. 24 h urinary protein quantitative (24 h TP), urine red blood cell (UM-RBC), serum tumor necrosis factor- 偽 (TNF- 偽) and type 鈪，

本文編號(hào)：2079522