本文選題：輕度胃腸炎 + 良性驚厥　； 參考：《蘇州大學(xué)》2013年碩士論文

【摘要】：目的：探討輕度胃腸炎伴嬰幼兒良性驚厥(Benign Infantile Convulsions with Mild Gastroenteritis, BICE)的臨床特點(diǎn)及預(yù)后。 方法：對(duì)2008年2月至2013年2月常州市第一人民醫(yī)院兒科住院治療的63例BICE患兒和69例急性胃腸炎不伴有驚厥患兒進(jìn)行臨床分析,病愈后予2個(gè)月～74個(gè)月的隨訪,回顧分析BICE臨床、實(shí)驗(yàn)室檢查結(jié)果及預(yù)后。49/63例BICE患兒行糞便人輪狀病毒(human rotavirus, HRV)抗原檢測(cè),比較分析12例糞便HRV抗原陽(yáng)性BICE患兒與37例陰性BICE患兒臨床及實(shí)驗(yàn)室檢查之間的異同。另比較分析63例BICE患兒和69例急性胃腸炎不伴驚厥患兒實(shí)驗(yàn)室檢查的差異。 結(jié)果：63例BICE患兒,年齡6個(gè)月～35個(gè)月；男27例,女36例；冬季發(fā)病22例,秋季發(fā)病37例。首次驚厥于腹瀉第1天15例,第2天23例,第3天21例,第4天4例。發(fā)作形式58/63例為全身性強(qiáng)直陣攣發(fā)作；5/63例為部分性發(fā)作,驚厥停止后未予抗癲癇治療。發(fā)作間期腦電圖4例輕度異常,1例示不正常腦電圖。血、尿、糞、肝功能、血生化、腦脊液、頭顱CT等檢查正常。神經(jīng)系統(tǒng)查體陰性。糞便HRV陽(yáng)性患兒血鈉、鈣含量低于HRV陰性者(131.31±1.94vs133.49±2.92,2.24±0.23vs2.43±0.15,P均0.05)。63例BICE患兒的血鈉較69例急性胃腸炎不伴驚厥患兒血鈉低(133.03±3.08vs135.37±4.50,P0.05)。隨訪4例復(fù)發(fā),其中1例發(fā)生熱性驚厥1次,隨訪期內(nèi)無(wú)轉(zhuǎn)化為癲癇病例。 結(jié)論：1.根據(jù)BICE臨床特點(diǎn),結(jié)合相關(guān)檢查,提示本病可能主要與輪狀病毒等感染有關(guān)。2.經(jīng)治療及隨訪,發(fā)現(xiàn)本病預(yù)后良好。
[Abstract]:Objective: to investigate the clinical features and prognosis of mild gastroenteritis with benign convulsions with Mild Gastroenteritis (Bice). Methods: from February 2008 to February 2013, 63 cases of Bice and 69 cases of children with acute gastroenteritis without convulsion in pediatrics of the first people's Hospital of Changzhou were analyzed. The patients were followed up for 2 months to 74 months after recovery. The clinical, laboratory results and prognosis of stool rotavirus (human rotavirus,) antigens in 49 / 63 cases were analyzed retrospectively. The differences and similarities between the clinical and laboratory tests of 12 cases of stool (human rotavirus, antigen positive children and 37 cases of negative Bice children were compared and analyzed. The difference of laboratory examination between 63 cases of nice and 69 cases of acute gastroenteritis without convulsion was analyzed. Results Sixty-three cases of Bee were aged from 6 months to 35 months, including 27 males and 36 females, 22 in winter and 37 in autumn. The first convulsion occurred on the first day (15 cases), the second day (23 cases), the third day (21 cases) and the fourth day (4 cases). There were 58 / 63 cases with generalized tonic-clonic seizure and 5 / 63 cases with partial seizure. No antiepileptic treatment was given after the convulsion stopped. Interictal electroencephalogram (EEG) showed slight abnormality in 4 cases and abnormal EEG in 1 case. Blood, urine, feces, liver function, blood biochemistry, cerebrospinal fluid, cranial CT and other normal examination. Nervous system test negative. The serum sodium and calcium content in stool HRV-positive children were lower than those in HRV-negative patients (131.31 鹵1.94vs133.49 鹵2.92 鹵2.24 鹵0.15) .63 cases of nice were lower than 69 cases of acute gastroenteritis without convulsion (133.03 鹵3.08vs135.37 鹵4.50 P 0.05). 4 cases were followed up, one of them developed febrile convulsion once, and there was no change to epilepsy during the follow-up period. Conclusion 1. According to the clinical characteristics of spice and related examination, it is suggested that the disease may be mainly related to rotavirus infection. After treatment and follow-up, it was found that the prognosis of the disease is good.
【學(xué)位授予單位】：蘇州大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2013
【分類號(hào)】：R725.7

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