本文選題：小兒哮喘 + 緩解期��； 參考：《南京中醫(yī)藥大學(xué)》2012年碩士論文

【摘要】：研究目的：哮喘是小兒時(shí)期常見(jiàn)的肺系疾病,有反復(fù)發(fā)作、遷延難愈的特點(diǎn),對(duì)兒童健康危害極大,而在哮喘緩解期對(duì)患兒進(jìn)行積極治療,以減輕和減少哮喘的發(fā)作是小兒哮喘治療的關(guān)鍵。本文通過(guò)觀察治療前后患兒哮喘的發(fā)作次數(shù)、發(fā)作時(shí)哮鳴音、發(fā)作時(shí)喘息、感冒次數(shù)、鼻塞鼻癢及面色、汗出、氣促及大便、舌象等指標(biāo)的變化,客觀評(píng)價(jià)中藥穴位敷貼結(jié)合口服中藥膏方治療小兒哮喘緩解期的臨床療效。 研究方法：選取符合診斷標(biāo)準(zhǔn)的哮喘緩解期患兒60例,以2：1的比例隨機(jī)分為試驗(yàn)組和對(duì)照組,最終收取試驗(yàn)組40例,對(duì)照組20例。治療前兩組患兒在性別、年齡、體重及病情方面,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),具有可比性。試驗(yàn)組用中藥穴位敷貼結(jié)合口服中藥膏方治療,對(duì)照組予單純口服中藥膏方治療。兩組均治療1個(gè)療程,隨訪3個(gè)月。療程結(jié)束后,比較兩組患兒主癥、次癥積分及中醫(yī)證候總積分的改善情況,評(píng)價(jià)兩種不同治療方案治療小兒哮喘緩解期的臨床療效。 研究結(jié)果：共完成研究觀察病例數(shù)共60例,其中治療組40例,對(duì)照組20例。統(tǒng)計(jì)結(jié)果如下： 1.治療后兩組患兒主癥改善：試驗(yàn)組在發(fā)作時(shí)哮鳴音及感冒發(fā)作次數(shù)方面,明顯優(yōu)于對(duì)照組(P0.01)；在改善哮喘發(fā)作時(shí)喘息方面,試驗(yàn)組優(yōu)于對(duì)照組(P0.05)；在鼻塞鼻癢方面,與對(duì)照組療效相似(P0.05)。 2.治療后兩組患兒次癥改善：試驗(yàn)組與對(duì)照組療效相似(P0.05)。 3.療效評(píng)價(jià)：試驗(yàn)組臨床痊愈、顯效、有效、無(wú)效例數(shù)為8、16、14、2,對(duì)照組臨床痊愈、顯效、有效、無(wú)效例數(shù)為2、4、10、4,臨床痊愈率、總有效率分別為治療組20.0%、95.0%,對(duì)照組為10.0%、80.0%,差異有統(tǒng)計(jì)學(xué)意義(P0.05),試驗(yàn)組優(yōu)于對(duì)照組。 4.試驗(yàn)組和對(duì)照組在治療過(guò)程和隨訪時(shí),均未發(fā)現(xiàn)副作用。 結(jié)論：中藥穴位敷貼結(jié)合中藥膏方和單純中藥膏方口服治療小兒哮喘緩解期均取得很好療效,前者療效優(yōu)于后者,臨床使用安全性好。
[Abstract]:Objective: asthma is a common pulmonary disease in childhood. It has the characteristics of repeated attacks and prolonged and difficult to heal. It is harmful to children's health, but the children are actively treated during the remission period of asthma. To alleviate and reduce the attack of asthma is the key to the treatment of asthma in children. The changes of asthma attacks, wheezing, colds, nasal congestion, itching and complexion, sweating, shortness of breath and stool, tongue appearance were observed before and after treatment. Objective to evaluate the clinical efficacy of acupoint application combined with oral ointment in the remission of childhood asthma. Methods: sixty children with asthma in remission period who met the diagnostic criteria were randomly divided into the experimental group and the control group at 2:1. Finally, 40 cases in the experimental group and 20 cases in the control group were collected. There was no significant difference in sex, age, weight and illness between the two groups before treatment. The experimental group was treated with traditional Chinese medicine acupoint application combined with oral Chinese medicine ointment, while the control group was treated with simple oral Chinese medicine ointment. Both groups were treated with a course of treatment and followed up for 3 months. After the course of treatment, the improvement of the main symptom, the secondary symptom score and the total score of TCM syndromes were compared between the two groups, and the clinical effect of two different treatment schemes on children asthma in remission period was evaluated. Results: a total of 60 cases were observed, including 40 cases in the treatment group and 20 cases in the control group. The results are as follows: 1. After treatment, the main symptoms of the two groups were improved: the experimental group was significantly better than the control group in terms of wheezing and the frequency of cold attack during the attack; the experimental group was superior to the control group in improving the wheezing during the attack of asthma, and in the nasal obstruction and itching, the treatment group was superior to the control group in improving the asthmatic attack. The curative effect was similar to that of the control group (P 0.05). After treatment, the improvement of secondary symptoms in the two groups: the treatment group and the control group were similar to the control group (P 0.05). Evaluation of curative effect: clinical recovery, remarkable effect, effective and ineffective cases were 816 / 14 / 2 in the experimental group, while in the control group, the clinical recovery, marked effect and effective were 2 / 4 / 10 / 10 / 4, and the clinical recovery rate was 4 / 10 / 4, respectively. The total effective rates were 20.0 and 10.0 in the treatment group and 10.0 and 80.0 in the control group, respectively. The difference was statistically significant (P 0.05), and the experimental group was better than the control group. No side effects were found in the treatment and follow-up in both the trial group and the control group. Conclusion: the Chinese medicine acupoint application combined with traditional Chinese medicine ointment and simple Chinese medicine ointment have good curative effect on children asthma in remission period, the former is better than the latter, and the clinical use safety is good.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R272

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