本文選題：急性下呼吸道感染 + 兒童�。� 參考：《中華醫(yī)院感染學(xué)雜志》2017年12期

【摘要】：目的探討住院急性下呼吸道感染患兒人冠狀病毒感染狀況,為臨床防治提供理論依據(jù)。方法選擇2013年1月-2015年12月醫(yī)院就診急性下呼吸道感染的患兒3140例,36例單純?nèi)斯跔畈《?HCoV)感染患兒為研究組,在其余3012例非人冠狀病毒感染患兒中選擇與研究組一般資料無差異的患兒60例為對照組;采集所有患兒入院1d內(nèi)的鼻咽吸取物或者鼻咽拭子標(biāo)本1份,并于72小時內(nèi)送檢;對3140例下呼吸道感染患兒中人冠狀病毒感染情況及臨床特征進(jìn)行分析。結(jié)果 3140例患兒共檢出流感病毒224例,呼吸道合胞病毒652例,多瘤病毒KI173例,多瘤病毒W(wǎng)U 192例,人偏肺病毒257例,人冠狀病毒128例,副流感病毒572例,腺病毒358例,鼻病毒584例其中人冠狀病毒感染陽性率為4.08%,單純感染患兒36例,其中HCoV-HKUI、HCoV-OC43、HCoV-229E、HCoV-NL63、HCoV-EMC、SARS-CoV分別為6例,12例、6例、6例、3例、3例;研究組患兒咳嗽、呼吸衰竭、腹瀉、發(fā)熱、喘息和低氧血癥比例顯著高于對照組(P0.05);27例患兒出現(xiàn)吸氣相濕Up音和雙肺呼氣相喘鳴音,30例患兒胸部影像學(xué)表現(xiàn)支氣管炎,3例為喉氣管炎,3例為毛細(xì)支氣管炎,9例患兒表現(xiàn)出肺部實(shí)變影,24例患兒表現(xiàn)出過度通氣現(xiàn)象。結(jié)論下呼吸道感染患兒人冠狀病毒感染,咳嗽為首發(fā)癥狀,同時伴隨呼吸急促、喘息,多數(shù)伴隨發(fā)熱,肺部聽診表現(xiàn)呼氣相高調(diào)喘鳴聲和細(xì)濕羅音,部分患兒伴有腹瀉癥狀。對于臨床診斷為以上癥狀的兒童,應(yīng)該積極采取措施,對患者感染病毒進(jìn)行檢測,進(jìn)行針對性治療。
[Abstract]:Objective to investigate the status of human coronavirus infection in hospitalized children with acute lower respiratory tract infection and to provide theoretical basis for clinical prevention and treatment. Methods A total of 3140 children with acute lower respiratory tract infection from January 2013 to December 2015 were selected as study group. 36 children with simple human coronavirus HCoV infection were selected as the study group. Among the other 3012 cases of non-human coronavirus infection, 60 cases were selected as control group, and 1 sample of nasopharynx drains or nasopharyngeal swabs was collected from all the children within one day of admission and submitted to examination within 72 hours. The clinical features of human coronavirus infection in 3140 children with lower respiratory tract infection were analyzed. Results A total of 224 cases of influenza virus, 652 cases of respiratory syncytial virus, 2 cases of polytumour virus KI173, 192 cases of polytumour virus, 257 cases of human metapulmonary virus, 128 cases of human coronavirus, 572 cases of parainfluenza virus and 358 cases of adenovirus were detected in 3140 children. The positive rate of human coronavirus infection was 4.08 in 584 cases of rhinovirus and 36 cases of infantile infection, including HCoV-HKUIHCoV-OC43, HCoV-229ECoV-NL63, HCoV-NL63, HCoV-EMCSARS-CoV, 6 cases of SARS-CoV, 6 cases of 6 cases of SARS-CoV infection, 3 cases of cough, respiratory failure, diarrhea, fever and fever in study group. The rates of wheezing and hypoxemia were significantly higher than those in the control group (27 cases) with inspiratory wet up and 30 cases with bronchitis and bronchiolitis. 3 cases were laryngotracheitis, 3 cases were bronchiolitis and 9 cases were capillary bronchitis. 24 children showed pulmonary hyperventilation. Conclusion in children with lower respiratory tract infection, cough is the first symptom, accompanied by shortness of breath, wheezing, and fever. The lung auscultation shows high breath tone and thin moist rale, and some children have diarrhea symptoms. For children clinically diagnosed with these symptoms, we should take active measures to detect the infected virus and carry out targeted treatment.
【作者單位】： 寧波市婦女兒童醫(yī)院兒內(nèi)科;
【分類號】：R725.6
，

本文編號：1974156