本文選題：醫(yī)院感染 + 多藥耐藥菌��； 參考：《中華醫(yī)院感染學(xué)雜志》2017年18期

【摘要】：目的分析心臟外科ICU患兒多藥耐藥菌(MDRO)聚集事件的控制過程,對(duì)醫(yī)院感染耐藥菌株聚集綜合干預(yù)策略進(jìn)行評(píng)價(jià)。方法前瞻性干預(yù)管理2014年1月-2016年12月小兒心外監(jiān)護(hù)2起多藥耐藥菌聚集事件,對(duì)照2008年1月-2013年12月4起聚集事件,對(duì)多藥耐藥菌預(yù)警時(shí)機(jī)、隔離措施執(zhí)行情況、手衛(wèi)生依從性、防護(hù)用品使用、常規(guī)環(huán)境消毒效果、抗菌藥物管理等一系列干預(yù)策略,進(jìn)行綜合評(píng)價(jià)。結(jié)果綜合干預(yù)后,耐藥菌聚集事件平均持續(xù)時(shí)間由28.25d縮短為14.50d,感染患兒耐藥菌清除率由41.18%上升為72.73%,干預(yù)前后比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);實(shí)施綜合干預(yù)措施后,臨床24h內(nèi)隔離措施執(zhí)行率、醫(yī)務(wù)人員手衛(wèi)生依從性、環(huán)境消毒達(dá)標(biāo)率均明顯提高(P0.05)。結(jié)論 MDRO綜合干預(yù)措施可以明顯縮短耐藥菌聚集事件的控制時(shí)間、提高感染患兒耐藥菌清除率。
[Abstract]:Objective to analyze the control process of multidrug resistant bacteria (MDR) aggregation events in children with ICU in cardiac surgery, and to evaluate the comprehensive intervention strategy of drug resistant strains in nosocomial infection (Nosocomial infection). Methods from January 2014 to December 2016, two multidrug resistant bacteria (MDR) aggregation events were managed by prospective intervention, compared with 4 events from January 2008 to December 2013, the timing of early warning of MDR bacteria and the implementation of isolation measures. A series of intervention strategies, such as hand hygiene compliance, protective equipment use, routine environmental disinfection effect, antimicrobial drug management, were comprehensively evaluated. Results after comprehensive intervention, the average duration of drug-resistant bacteria aggregation events was shortened from 28.25 days to 14.50 days, and the clearance rate of drug-resistant bacteria increased from 41.18% to 72.73. There was a significant difference between before and after intervention (P 0.05). The rate of carrying out isolation measures in 24 hours, the compliance of hand hygiene of medical personnel, and the rate of environmental disinfection reaching the standard were significantly improved (P 0.05). Conclusion the comprehensive intervention of MDRO can significantly shorten the control time of drug resistant bacteria aggregation events and improve the clearance rate of drug resistant bacteria in infective children.
【作者單位】： 首都醫(yī)科大學(xué)附屬北京安貞醫(yī)院醫(yī)院感染管理辦公室;首都醫(yī)科大學(xué)附屬北京安貞醫(yī)院小兒心臟外科中心;
【基金】：國(guó)家自然科學(xué)基金資助項(xiàng)目(81371443)
【分類號(hào)】：R726.5

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