本文選題：哮喘　切入點(diǎn)：兒童哮喘控制測(cè)試　出處：《青島大學(xué)》2017年碩士論文

【摘要】：目的:探討不同年齡兒童哮喘控制測(cè)試(Childhood asthma control test,C-ACT)與肺通氣功能的關(guān)系。方法:選取2015年5月-2016年5月在我院確診并進(jìn)行規(guī)范化治療的支氣管哮喘患兒164例,其中男99例,女65例;平均年齡(8.43±2.08)歲,將所有入選患兒根據(jù)年齡分為低年齡組(n=80):年齡為4-6歲,平均年齡為(5.28±0.39)歲;高年齡組(n=84):年齡為7-11歲,平均年齡(9.04±1.79)歲。觀察治療前、治療后6個(gè)月哮喘患兒的C-ACT評(píng)分和肺功能相關(guān)指標(biāo)(FEV1%、PEF%、MEF50%)的變化,探討兒童哮喘控制測(cè)試與肺功能的相關(guān)性。結(jié)果:(1)治療前,低年齡組哮喘患兒的C-ACT評(píng)分為15.7±2.41,FEV1%、PEF%和MEF50%分別為52.1±11.47、51.4±10.91和58.3±16.04;C-ACT評(píng)分與FEV1%、PEF%、和MEF50%的相關(guān)系數(shù)r分別為0.174、0.274和0.241,相對(duì)應(yīng)的P值分別為0.061、0.151和0.121,P0.05,均沒(méi)有顯著性差異,無(wú)統(tǒng)計(jì)學(xué)意義。高年齡組哮喘患兒的C-ACT評(píng)分為15.6±2.44,FEV1%、PEF%、MEF50%分別為51.33±10.92、52.1±12.29和59.2±16.33;C-ACT評(píng)分與FEV1%、PEF%、MEF50%的相關(guān)系數(shù)r分別為0.341、0.392和0.412,相對(duì)應(yīng)的P值分別為0.010、0.021和0.008,P0.05,存在顯著的正相關(guān),有統(tǒng)計(jì)學(xué)意義。(2)治療后6個(gè)月,低年齡組哮喘患兒的C-ACT評(píng)分為22.3±2.39,FEV1%、PEF%、MEF50%分別為73.5±16.38、71.8±12.17和78.5±15.16;C-ACT評(píng)分與FEV1%、PEF%、MEF50%的相關(guān)系數(shù)r分別為0.183、0.263和0.250,對(duì)應(yīng)的P值分別為0.082、0.141和0.132,P0.05,均沒(méi)有顯著性差異,無(wú)統(tǒng)計(jì)學(xué)意義。高年齡組哮喘患兒的C-ACT評(píng)分為22.8±2.54,FEV1%、PEF%、MEF50%分別為77.95±16.91、75.52±16.53和77.4±19.26;C-ACT評(píng)分與FEV1%、PEF%、MEF50%的相關(guān)系數(shù)r分別為0.352、0.402和0.432,相對(duì)應(yīng)的P值分別為0.011、0.019、0.005,存在顯著的正相關(guān)。C-ACT評(píng)分以及肺功能相關(guān)指標(biāo)治療前后均有顯著性提高,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:作為一種評(píng)估哮喘控制情況的方法,更適用于高年齡組(7-11歲)患兒。
[Abstract]:Objective: to investigate the relationship between childhood asthma control test C-ACTand pulmonary ventilation function in children of different ages. Methods: 164 children with bronchial asthma diagnosed and treated with standardized treatment from May 2015 to May 2016 were selected, including 99 males. There were 65 females with an average age of 8.43 鹵2.08 years. All the children were divided into low age group (4-6 years old, mean age 5.28 鹵0.39) and older group (7-11 years, mean age 9.04 鹵1.79). After 6 months of treatment, the changes of C-ACT score and pulmonary function related index (FEV1 / PEF50) in children with asthma were investigated, and the correlation between the control test of asthma and pulmonary function was investigated. The C-ACT scores of PEF% and MEF50% were 52.1 鹵11.47 鹵51.4 鹵10.91 and 58.3 鹵16.04 鹵16.04 and the correlation coefficients r were 0.1740.274 and 0.241, respectively. The corresponding P values were 0.061 鹵0.151 and 0.121%, respectively, no significant difference was found between the scores of PEF% and FEV1-PEF5.There was no significant difference between the scores of PEF% and FEV1, and the correlation coefficients (r) of 50% and 50% of the scores were 0.1740.274 and 0.241, respectively, and the corresponding P values were 0.061 and 0.121, respectively. There was no statistical significance between the C-ACT score of 15. 6 鹵2. 44 and FEV1 scores of 51.33 鹵10. 92 鹵52. 1 鹵12. 29 and 59.2 鹵16. 33% of the patients with asthma and the correlation coefficient r of 50% of FEV1 PEFI with FEV1 + PEF0. 392 and 0.412, respectively. The corresponding P values were 0. 010. 021 and 0. 008? P5, respectively. There was a significant positive correlation between the scores, and the correlation coefficients were 0. 341 and 0. 412, respectively, and the corresponding P values were 0. 010. 021 and 0. 008? P5, respectively. After 6 months of treatment, the C-ACT scores of low age children with asthma were 22.3 鹵2.39 FEV1 and 73.5 鹵16.38%, 73.5 鹵16.38 鹵71.8 鹵12.17 and 78.5 鹵15.16, respectively. The correlation coefficient r between the scores of C-ACT and FEV1 were 0.183 鹵0.263 and 0.250, respectively, and the corresponding P values were 0.082 0.141 and 0.132 P 0.05, respectively. There was no statistical significance. The C-ACT scores of children with asthma were 22.8 鹵2.54FEV1and PEF50% were 77.95 鹵16.91g 75.52 鹵16.53,77.4 鹵19.26m C-ACT and the correlation coefficient r of FEV1PEFU MEF50% were 0.3520.402 and 0.432respectively, and the corresponding P values were 0.0110.0190.005, respectively. There was significant positive correlation between C-ACT score and pulmonary function phase score (P = 0.0110.0190.005). Before and after treatment, there was a significant increase in the index of Guan, Conclusion: as a method to evaluate the control of asthma, it is more suitable for children aged 7-11 years.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：R725.6

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 陳碧芬;王建雄;Q，

本文編號(hào)：1690049