本文選題：兒童　切入點(diǎn)：Bartter綜合征　出處：《四川大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2017年05期

【摘要】：目的分析兒童Bartter綜合征臨床特征,探討臨床極易忽視的不典型表現(xiàn),從而達(dá)到早期診斷、早期干預(yù)的目的,改善其預(yù)后。方法收集1999年1月至2016年12月四川大學(xué)華西第二醫(yī)院兒科收治的26例兒童Bartter綜合征的病例資料,分析其臨床特征。結(jié)果本病主要兒童期起病,3歲前發(fā)病約61.5%,該病起病首發(fā)癥狀多樣化,以嘔吐、納差起病約占53.8%,生長(zhǎng)發(fā)育落后高達(dá)80.8%,伴有不同程度的低鉀,低鈉、低氯性堿中毒及脫水等水電解質(zhì)紊亂,腎素及血管緊張素Ⅱ增高,生長(zhǎng)發(fā)育及智力低下是兒童Bartter的特點(diǎn)。結(jié)論當(dāng)患兒出現(xiàn)嘔吐、納差,生長(zhǎng)發(fā)育落后,同時(shí)伴有低鉀血癥性代謝性堿中毒者,應(yīng)該警惕Bartter綜合征,及早行腎素-血管緊張素-醛固酮檢測(cè),必要時(shí)行基因檢測(cè)。
[Abstract]:Objective to analyze the clinical features of Bartter syndrome in children and to explore the atypical manifestations which are easy to be neglected in order to achieve early diagnosis and early intervention. Methods from January 1999 to December 2016, 26 children with Bartter syndrome were collected. Results the onset of the disease was about 61.5 before the age of 3 years of age. The initial symptoms of the disease were diversified, vomiting, anorexia accounted for 53.8%, growth and development lagged as high as 80.8, accompanied by different degrees of low potassium, low sodium. Low chlorine alkalosis, dehydration and other water and electrolyte disorders, increased renin and angiotensin 鈪，

本文編號(hào)：1685513