發(fā)布時間：2018-03-30 06:46

  本文選題：防哮飲　切入點：布地奈德　出處：《中藥材》2017年06期

【摘要】：目的:研究防哮飲聯(lián)合吸入布地奈德對肺氣虛證緩解期兒童哮喘的臨床療效,并探討其對兒童肺功能和氣道反應(yīng)性的影響。方法:選取2015年6月~2016年6月在浙江省新華醫(yī)院兒科就診的112例肺氣虛證緩解期哮喘患兒隨機分為觀察組和對照組,對照組患兒給予霧化吸入布地奈德治療,觀察組患兒霧化吸入布地奈德并口服防哮飲,療程為3個月,比較治療前后兩組患兒的中醫(yī)證候積分,并進行綜合臨床療效評價,檢測兩組患兒的肺功能及呼吸道反應(yīng)性。結(jié)果:(1)治療后觀察組患兒鼻癢噴嚏、流涕、咳嗽、氣短、出汗、面色、語音、乏力、畏風(fēng)等中醫(yī)證候積分較對照組患兒顯著降低(P0.01);(2)觀察組患兒總有效率顯著高于對照組(P0.05);(3)治療后觀察組患兒肺功能指標(biāo)VT/kg、Ti/Te、TPTEF/TE、VPEF/VE、TEF25%、TEF50%及TEF75%均較對照組顯著升高(P0.01),Rr和PEF較對照組顯著降低(P0.01);(4)治療后觀察組患兒呼吸道反應(yīng)性參數(shù)D_(min)、C_(min)、SGrs和SGrs/Grs均較對照組顯著升高(P0.01)。結(jié)論:防哮飲聯(lián)合吸入布地奈德治療肺氣虛證緩解期哮喘患兒具有較好的臨床療效,可顯著改善患兒的肺功能并降低其呼吸道反應(yīng)性。
[Abstract]:Objective: to study the clinical effect of Fangxiao decoction combined with inhaled budesonide on asthmatic children with lung qi deficiency syndrome in remission period. Methods: from June 2015 to June 2016, 112 children with asthma in remission of lung qi deficiency syndrome were randomly divided into observation group and control group. Children in the control group were treated with budesonide, and those in the observation group were treated with budesonide and oral budesonide for 3 months. The scores of TCM syndromes of the two groups were compared before and after treatment, and the comprehensive clinical efficacy was evaluated. Results after the treatment, the children in the observation group had itching, sneezing, runny, coughing, shortness of breath, sweating, complexion, speech, fatigue, etc. The total effective rate of the observation group was significantly higher than that of the control group (P 0.05)) after treatment, the pulmonary function index of the observation group was significantly higher than that of the control group. The pulmonary function indexes of the observation group were significantly higher than that of the control group. The pulmonary function indexes of the observation group were 50% and 75% higher than those of the control group. After treatment, the respiratory reactivity parameters of the observation group were significantly higher than that of the control group. Conclusion: the combination of P0.01and inhaled budesonide has a better clinical effect in the treatment of asthmatic children with asthenia of lung qi syndrome. It can significantly improve the pulmonary function and reduce the respiratory tract reactivity in children.
【作者單位】： 浙江省新華醫(yī)院呼吸科;浙江省中醫(yī)院兒科;
【基金】：浙江省中醫(yī)藥優(yōu)秀青年人才基金計劃項目(2012ZQ013)
【分類號】：R725.6

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