本文選題：五運六氣　切入點：肺炎支原體感染　出處：《湖北中醫(yī)藥大學(xué)》2012年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：本課題旨在研究武漢地區(qū)2001年～2010年的氣候特點及兒童肺炎支原體高發(fā)年份和高發(fā)季節(jié),并通過中醫(yī)五運六氣理論推算出2001年～2010年武漢地區(qū)的氣候特點及流行疾病的高發(fā)年份,從而探討兩者之間的相關(guān)性。 方法：收集武漢地區(qū)2001年1月～2010年12月因呼吸道感染在武漢市協(xié)和醫(yī)院、武漢市同濟醫(yī)院、湖北省婦幼保健院、武漢市第一醫(yī)院兒科和武漢市兒童醫(yī)院就診的患兒102547例,其中男63237例,女39310例,年齡最小1個月,最大14歲。采集患者靜脈血,分離血清,采用ELISA方法(酶聯(lián)免疫吸附試驗)檢測患者血清中的特異性MP-IgM抗體,操作嚴(yán)格按照試劑說明進行。對不同年份,不同季度的MP-IgM抗體的陽性率進行統(tǒng)計。實驗結(jié)果分析采用SPSS13.0統(tǒng)計軟件,分類資料用x2檢驗,計量資料用t檢驗,等級資料用Ridit檢驗。并收集2001年1月～2010年12月武漢地區(qū)每月氣象資料,來自湖北省氣象局。 結(jié)果：1.該實驗結(jié)果顯示2001、2002、2003、2004、2005、2006、2007、2008、2009、2010年的陽性率分別為6.72%、16.52%、25.93%、21.63%、16.63%、14.98%、22.71%、15.79%、12.23%、16.12%。其中以2003年最高為25.93%,2001年最低為6.72%。2003的陽性率顯著高于2001年(x2=130.505,P0.01)。2001年～2010年的第一季度、第二季度、第三季度和第四季度的陽性率分別為17.72%、9.63%、12.87%和23.18%。第四季度的陽性率顯著高于第一季度、第二季度和第三季度(χ2分別為210.995、1796.083、925.830,P0.01)。2.通過五運六氣理論推演武漢地區(qū)的氣候特點與武漢地區(qū)實際氣候特點相符率不高,但其推算流行疾病的高發(fā)年份與武漢地區(qū)兒童肺炎支原體的高發(fā)年份一致,推算肺系疾病的高發(fā)季節(jié)與武漢地區(qū)兒童肺炎支原體的高發(fā)季節(jié)一致。 結(jié)論：通過中醫(yī)五運六氣理論推演武漢地區(qū)的氣候特點存在一定的可行性,推算武漢地區(qū)兒童肺炎支原體感染的高發(fā)年份、高發(fā)季節(jié)具有一定的準(zhǔn)確性。
[Abstract]:Objective: to study the climatic characteristics and the year and season of high incidence of mycoplasma pneumoniae in Wuhan from 2001 to 2010. The climatic characteristics and the year of high prevalence of epidemic diseases in Wuhan from 2001 to 2010 were calculated by the theory of "five Transport and six Qi" in traditional Chinese Medicine, and the correlation between them was discussed. Methods: from January 2001 to December 2010, 102547 cases of children with respiratory tract infection were collected from Xianhe Hospital of Wuhan City, Tongji Hospital of Wuhan City, Maternal and Child Health Hospital of Hubei Province, Pediatrics Department of the first Hospital of Wuhan City and Children's Hospital of Wuhan City. Among them, 63237 males and 39310 females, aged from 1 month to 14 years, collected venous blood, isolated serum and detected the specific MP-IgM antibody in the serum of patients by ELISA assay (enzyme-linked immunosorbent assay), and the specific MP-IgM antibody in the serum of the patients was determined by enzyme-linked immunosorbent assay (Elisa). The operation was carried out strictly according to the reagent instructions. The positive rate of MP-IgM antibody in different years and different quarters was counted. The SPSS13.0 statistical software was used to analyze the experimental results, the classification data was tested by x2, and the measurement data was tested by t test. The grade data were checked by Ridit and collected monthly meteorological data from January 2001 to December 2010 in Wuhan from Hubei Meteorological Bureau. Results 1. The results of this experiment show that the positive rates of 2001 / 2002 / 2003 / 2005 / 2007 / 2008 / 2009, respectively, on 2010 were 6.722 / 16.522 and 25.932 / 21.63A, respectively. The positive rates were significantly higher in the first quarter from 2001 to 2001, and in the second quarter of 2001, when the highest was 25.933 in 2003, and the lowest in 2001 was 6.722.05, P 0.01.The highest was 25.93in 2003 and the lowest 6.725.2003 in 2001. The positive rates in the third quarter and 4th quarter were 17.72% and 23.18%, respectively. The positive rates were significantly higher in the third quarter than in the first quarter. In the second quarter and the third quarter (蠂 ~ 2 = 210.995 / 1796.083 / 925.830 / P0.01 / 2 respectively), the climatic characteristics of Wuhan region were deduced by the theory of "five transport and six gases", and the coincidence rate between the climatic characteristics and the actual climatic characteristics in Wuhan was not high. But the year of high incidence of epidemic disease was consistent with that of childhood mycoplasma pneumoniae in Wuhan area, and the high incidence season of pulmonary diseases was consistent with that of children with mycoplasma pneumoniae in Wuhan area. Conclusion: it is feasible to extrapolate the climatic characteristics of Wuhan area by the theory of "five Transport and six Qi" in traditional Chinese Medicine. The high incidence year of mycoplasma pneumoniae infection in children in Wuhan area is calculated, and the high incidence season has certain accuracy.
【學(xué)位授予單位】：湖北中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R725.6

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