本文選題：孤獨(dú)性障礙　切入點(diǎn)：催產(chǎn)素　出處：《重慶醫(yī)學(xué)》2017年14期 　論文類(lèi)型：期刊論文

【摘要】：目的探討孤獨(dú)癥兒童與健康兒童血清催產(chǎn)素水平差異及其與孤獨(dú)癥兒童社交能力的關(guān)系。方法選取3~5歲孤獨(dú)癥患兒25例與健康兒童20例分別接受血清催產(chǎn)素水平測(cè)量,采用社交反應(yīng)量表評(píng)定孤獨(dú)癥兒童社交能力。結(jié)果獨(dú)立樣本t檢驗(yàn)顯示孤獨(dú)癥患兒血清催產(chǎn)素水平低于健康兒童,比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。孤獨(dú)癥兒童患者血清催產(chǎn)素水平與其社交能力呈負(fù)相關(guān)(r=-0.735,P0.01)。多元線性回歸模型分析顯示孤獨(dú)癥兒童患者中,催產(chǎn)素水平是影響社交能力的因素(F=11.931,P0.01)。結(jié)論與健康兒童相比,孤獨(dú)癥兒童患者存在血清催產(chǎn)素水平異常,血清催產(chǎn)素水平可能是影響其社交能力的因素。
[Abstract]:Objective to explore the difference of serum oxytocin level between autistic and healthy children and its relationship with social ability of autistic children. Methods Serum oxytocin levels were measured in 25 autistic children aged 3 ~ 5 years and 20 healthy children. Results the independent sample t test showed that the serum oxytocin level of autistic children was lower than that of healthy children. The serum oxytocin level in autistic children was negatively correlated with their social ability. The multivariate linear regression analysis showed that the serum oxytocin level in autistic children was negatively correlated with their social ability. Conclusion compared with healthy children, the serum oxytocin level in autistic children is abnormal, and the serum oxytocin level may be the factor that affects the social ability of autistic children.
【作者單位】： 重慶市第九人民醫(yī)院兒童孤獨(dú)癥康復(fù)治療中心;重慶市第九人民醫(yī)院藥學(xué)研究室;重慶市第九人民醫(yī)院藥劑科;
【基金】：重慶市醫(yī)學(xué)科研項(xiàng)目(20143047)
【分類(lèi)號(hào)】：R749.94
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本文編號(hào)：1627384