音樂治療對早產(chǎn)兒腦電活動及行為神經(jīng)發(fā)育的作用
發(fā)布時間:2018-03-12 23:08
本文選題:音樂治療 切入點:早產(chǎn)兒 出處:《廣州中醫(yī)藥大學》2017年碩士論文 論文類型:學位論文
【摘要】:目的:探討音樂治療(莫扎特音樂和五行音樂)對早產(chǎn)兒腦電活動和行為神經(jīng)發(fā)育的作用。方法:使用前瞻性隨機對照試驗方法,將2016年02月至2017年01月在廣州中醫(yī)藥大學附屬南海婦產(chǎn)兒童醫(yī)院新生兒科住院的胎齡在34-36周、無神經(jīng)系統(tǒng)疾病的早產(chǎn)兒納入研究。經(jīng)過樣本量估算和隨機分配,共納入90例受試者,莫扎特音樂組30例,五行音樂組30例,另有用于對照觀察的空白對照組30例。莫扎特音樂組和五行音樂組在生后第3天開始每天進行2次音樂治療,每次時長為10分鐘,音量控制在40dB,莫扎特音樂組的音樂素材為莫扎特鋼琴奏鳴曲,五行音樂組為羽音,空白對照組不予音樂治療。比較音樂治療開始前和音樂治療過程中原始腦電圖(EEG)腦電頻譜的差異。比較生后第3天和生后第14天振幅整合腦電圖(aEEG)的背景活動連續(xù)性、振幅下邊界和帶寬的差異。比較生后第3天和生后第14天行為神經(jīng)評分(NBNA)的差異。受試者入組和出院前均行快速聽覺腦干誘發(fā)電位檢查,以了解音樂治療的安全性。結(jié)果:1、與音樂治療前比較,音樂治療過程中的腦電頻譜有顯著變化,其中莫扎特音樂組以α頻段(P㩳0.01)、β頻段(P㩳0.05)的增多為主,五行音樂組以θ頻段的增多為主(P㩳0.05)。2、生后第14天,莫扎特音樂組(P㩳0.05)和五行音樂組(P㩳0.01)的aEEG振幅下邊界均高于空白對照組;莫扎特音樂組(P㩳0.05)和五行音樂組(P㩳0.01)的aEEG帶寬均窄于空白對照組。3、生后第14天,莫扎特音樂組(P㩳0.01)和五行音樂組(P㩳0.05)的NBNA總分均高于空白對照組;莫扎特音樂組和五行音樂組的NBNA視聽定向力加分均高于空白對照組(P均0.01)。4、莫扎特音樂組和五行音樂組受試者在音樂治療期間未發(fā)現(xiàn)不良反應(yīng),出院前再次行快速聽覺腦干誘發(fā)電位檢查均未發(fā)現(xiàn)異常。結(jié)論:1、音樂治療過程中可引起早產(chǎn)兒腦電頻譜的變化。2、音樂治療可促進早產(chǎn)兒腦電背景活動的成熟。3、音樂治療可改善早產(chǎn)兒的行為神經(jīng)發(fā)育。4、音樂治療安全可靠。
[Abstract]:Objective: to investigate the effects of music therapy (Mozart music and five elements music) on brain electrical activity and behavioral nerve development in premature infants. From February 2016 to January 2017, the gestational age of preterm infants without nervous system diseases was 34-36 weeks in Nanhai Maternity and Childhood Hospital, Guangzhou University of traditional Chinese Medicine. The samples were estimated and randomly distributed. A total of 90 subjects were included: Mozart music group (30 cases), five elements music group (30 cases) and blank control group (30 cases). Mozart music group and Wuxing music group began to receive music therapy twice a day on the third day after birth. Each time is 10 minutes, volume control is 40 dB, Mozart group music material for Mozart piano sonata, five elements of music group for plume, Blank control group was not treated with music. The difference of EEG spectrum before and during music therapy was compared. The continuity of background activity of amplitude integrated EEG (EEGE) was compared on the 3rd day after birth and on the 14th day after birth. The differences of amplitude boundary and bandwidth were compared between postnatal day 3 and postnatal day 14. The subjects underwent rapid auditory brainstem evoked potential (BAEP) examination before and after admission. Results: 1, compared with before music therapy, there were significant changes in EEG spectrum during music therapy, especially in Mozart music group. 0.01g, 尾 band P? The increase of theta band is the main factor in the five elements music group, and the increase of theta band is the main factor in the five elements music group. 0.05. 2, 14 days after birth, Mozart music group? 0. 05) and five elements music group P? The lower boundary of aEEG amplitude in the Mozart music group was higher than that in the blank control group. 0. 05) and five elements music group P? The bandwidth of aEEG was narrower than that of the blank control group (0.01). On the 14th day after birth, the Mozart music group had the same aEEG bandwidth as the control group. (0. 01) and five elements music group (P0. 01)? The total scores of NBNA in Mozart group and Wuxing music group were higher than those in blank control group (P < 0.01), and no adverse reactions were found in Mozart music group and Wuxing music group during music therapy, and the scores of NBNA in Mozart music group and Wuxing music group were higher than those in blank control group (P < 0.01). No abnormality was found in the rapid auditory brainstem evoked potential examination before discharge. Conclusion: 1: 1, music therapy can cause the changes of EEG spectrum of premature infants. 2. Music therapy can promote the maturation of EEG background activity of premature infants. Music therapy can improve behavioral neurodevelopment of preterm infants, and music therapy is safe and reliable.
【學位授予單位】:廣州中醫(yī)藥大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R722.6
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