本文選題：兒童　切入點(diǎn)：左腎靜脈壓迫綜合征　出處：《福建中醫(yī)藥大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：通過(guò)觀察活血益腎法治療兒童左腎靜脈壓迫綜合征的臨床療效,總結(jié)導(dǎo)師臨床經(jīng)驗(yàn),提高臨床療效。方法：收集2010年至2014年期間我院左腎靜脈壓迫綜合征患兒30例,采用隨機(jī)數(shù)字表法分為中藥治療組(簡(jiǎn)稱A組)和空白對(duì)照組(簡(jiǎn)稱B組)各15例。兩組的性別、年齡、病程分布均具有可比性(P=0.4660.05,P=0.7150.05, P=0.7100.05)。A組采用自擬的活血益腎方(藥物組成：桃仁5g、紅花5g、當(dāng)歸5g、赤芍9g、白茅根15g、生地黃15g、山藥12g、山茱萸9g、茯苓9g、牡丹皮15g等)治療,水煎,日1劑,2次/日,6個(gè)月為1個(gè)療程；B組不采取任何治療措施,觀察6個(gè)月。觀察兩組初診時(shí)和初診后6個(gè)月的左腎靜脈內(nèi)徑值、尿紅細(xì)胞計(jì)數(shù),并觀察中藥治療組治療前后的臨床癥狀體征。結(jié)果：(1)初診時(shí),A組與B組比較：仰臥位和脊柱后伸位時(shí)的LRV內(nèi)徑比值均無(wú)顯著差異(P=0.0900.05,P=0.7140.05),具有可比性；初診后6個(gè)月,A組仰臥位和脊柱后伸位時(shí)的LRV內(nèi)徑比值明顯小于B組,差異非常顯著(P=-0.0120.05,P=0.0070.01)；中藥治療組治療6個(gè)月后,仰臥位和脊柱后伸位時(shí)的LRV內(nèi)徑比值明顯小于治療前,差異非常顯著(P=0.0000.01,P=0.0000.01)。(2)初診時(shí),A組的尿紅細(xì)胞計(jì)數(shù)與B組比較無(wú)顯著差異(P=-0.5020.05),具有可比性；初診后6個(gè)月,A組的尿紅細(xì)胞計(jì)數(shù)明顯少于B組,差異非常顯著(P=0.0000.01)；中藥治療組治療6個(gè)月后的尿紅細(xì)胞計(jì)數(shù)明顯少于治療前,差異非常顯著(P=0.0000.01)。(3)中藥治療組的臨床療效：治愈5例,顯效8例,無(wú)效2例,總有效率86.6%。結(jié)論：活血益腎法治療兒童左腎靜脈壓迫綜合征,可以降低LRV內(nèi)徑比值、減少尿紅細(xì)胞的排泄,從而改善臨床癥狀和體征,提高臨床有效率�；钛婺I法通過(guò)改善腎臟血液循環(huán),降低LRV內(nèi)徑比值,達(dá)到降低LRV壓力,改善臨床癥狀的目的。
[Abstract]:Objective: to observe the clinical effect of activating blood circulation and tonifying the kidney in treating left renal vein compression syndrome in children, summarize the clinical experience of tutor and improve the clinical effect. Methods: from 2010 to 2014, 30 cases of left renal vein compression syndrome were collected in our hospital. A randomized digital table method was used to divide Chinese medicine treatment group (group A for short) and blank control group (group B for short) with 15 cases each. The course of disease in group A was treated with self-made prescription for activating blood circulation and tonifying kidney (drug composition: peach seed 5g, safflower 5g, Angelica sinensis 5g, Radix Paeoniae rubra 9g, Radix Alba 15g, raw yellow 15g, yam 12g, Cornus officinalis 9g, Poria cocos 9g, peony skin 15g). The left renal vein diameter and urine red blood cell count were observed at first visit and 6 months after treatment in group B without any treatment. The clinical symptoms and signs before and after treatment in traditional Chinese medicine treatment group were observed. Results compared with group B at first visit, there was no significant difference in the ratio of LRV inner diameter in supine position and spinal extension position. The ratio of LRV diameter in supine position and spinal extension position in group A was significantly lower than that in group B at 6 months after initial diagnosis, and the difference was very significant (P < 0.01). After 6 months of treatment, the ratio of LRV diameter in supine position and spinal extension position in Chinese medicine treatment group was significantly lower than that in group B, and the ratio of LRV diameter in supine position and spinal extension position was significantly lower than that in group B after 6 months of treatment. There was no significant difference in urine erythrocyte count between group A and group B at the beginning of diagnosis, and the urine erythrocyte count in group A was significantly lower than that in group B at 6 months after the first visit, and the urine erythrocyte count in group A was significantly lower than that in group B at 6 months after initial diagnosis, and there was no significant difference between group A and group B in urine erythrocyte count. The number of urine red blood cells in the treatment group was significantly lower than that before treatment, and the difference was very significant (P < 0.05). The clinical efficacy of the Chinese medicine treatment group was as follows: 5 cases cured, 8 cases markedly effective, and 2 cases ineffective. Conclusion: the treatment of left renal vein compression syndrome in children by activating blood circulation and tonifying the kidney can reduce the ratio of LRV inner diameter, reduce the excretion of urine red blood cells and improve the clinical symptoms and signs. The method of activating blood circulation and tonifying the kidney can reduce the pressure of LRV and improve the clinical symptoms by improving the circulation of kidney and reducing the ratio of LRV inner diameter.
【學(xué)位授予單位】：福建中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R272

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