本文關(guān)鍵詞： 維漢新生兒 小時膽紅素水平 百分位曲線圖 高危因素　出處：《新疆醫(yī)科大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：繪制維吾爾族和漢族健康晚期早產(chǎn)兒及足月兒生后120小時內(nèi)經(jīng)皮膽紅素百分位曲線圖,分析相關(guān)影響因素,比較維吾爾族和漢族新生兒小時膽紅素變化趨勢及高膽紅素血癥發(fā)生率,為臨床診治提供依據(jù)。方法：選擇2013年2、4、6、8、10、12月新疆醫(yī)科大學(xué)第一附屬醫(yī)院及烏魯木齊市婦幼保健院產(chǎn)科出生的維吾爾族及漢族胎齡≥35周且出生體重≥2000g的健康新生兒2131例為研究對象,詳細(xì)記錄可能與新生兒黃疸有關(guān)的性別、胎齡、分娩方式、出生體重、喂養(yǎng)方式、開奶時間、胎便排出時間、胎膜早破、頭顱血腫情況,采用日本美能達(dá)JM-103型經(jīng)皮膽紅素測定儀監(jiān)測其生后3-5天經(jīng)皮膽紅素值(TCB),2次/日,每例新生兒至少有6次測量值,分別計算每一時段的TCB百分位數(shù)(P40,P75,P95),并繪制成曲線圖,同時將相關(guān)圍產(chǎn)因素對新生兒高膽紅素血癥的影響,分別進(jìn)行單因素χ2檢驗和多因素Logistic回歸分析,找出其相關(guān)因素。結(jié)果：本研究經(jīng)皮膽紅素峰值出現(xiàn)時間為時齡92～120小時；在同一時齡,P新(40,75,95)均高于國內(nèi)余章斌等研究P國內(nèi),(40,75,95),本研究中漢族新生兒經(jīng)皮膽紅素P漢(40,75,95)均高于P國內(nèi)(40,75,95),與本研究中漢族新生兒經(jīng)皮膽紅素P維(40,75,95),其中,P國內(nèi)(40,75,95)高于P維(40,75,95);P95曲線上升速度快于P75和P40曲線；漢族新生兒高膽紅素血癥發(fā)病率高于維吾爾族新生兒,χ2=71.523,P0.01,差異有統(tǒng)計學(xué)意義；早產(chǎn)、剖宮產(chǎn)、母乳喂養(yǎng)、漢族、開奶時間、胎便排出時間為發(fā)生新生兒高膽紅素血癥的獨立危險因素。結(jié)論：小時膽紅素百分位曲線圖反映了生后膽紅素水平的變化趨勢,對新生兒高膽紅素血癥具有一定的評估價值；維吾爾族和漢族新生兒膽紅素水平隨著日齡的增長逐漸升高,其中漢族新生兒生后小時膽紅素水平上升速率較維吾爾族新生兒高,高膽紅素血癥的發(fā)病率亦高于維吾爾族新生兒；早產(chǎn)、剖宮產(chǎn)、母乳喂養(yǎng)、漢族、開奶時間、胎便排出時間是發(fā)生新生兒高膽紅素血癥的獨立危險因素。
[Abstract]:Objective: to draw the percutaneous bilirubin percentile curves within 120 hours after birth of advanced premature infants and full-term infants in Uygur and Han nationality, and to analyze the related influencing factors. To compare the change trend of neonatal bilirubin and the incidence of hyperbilirubinemia in Uygur nationality and Han nationality. Methods: to provide evidence for clinical diagnosis and treatment. Methods: a new type of health was selected from the first affiliated Hospital of Xinjiang Medical University and Urumqi Maternal and Child Health Hospital in December. The gestational age of Uygur and Han nationality was more than 35 weeks and the birth weight was more than 2000g. 2131 newborns were studied. Record in detail the sex, gestational age, mode of delivery, birth weight, feeding method, time of milk opening, time of fecal excretion, premature rupture of membranes, cranial hematoma, which may be related to neonatal jaundice. The transdermal bilirubin value of Minolta type JM-103 was measured twice a day in 3-5 days after birth. The TCB percentile of each newborn was calculated at least 6 times per day, and the TCB percentile of P40 / P75 / P95 / day was calculated, and the curves were plotted. At the same time, the influence of perinatal factors on neonatal hyperbilirubinemia was analyzed by univariate 蠂 2 test and multivariate Logistic regression analysis. At the same time, it was higher than that of Yu Zhangbin in China (P < 0.05). The transdermal bilirubin of Han nationality newborns in this study was higher than that in P country (P = 40755 / 95), and it was higher than that of Chinese neonates (P = 40755 / 95), and it was higher than that of Chinese neonates of Han nationality (P = 40755 / 95), among them, there was no significant difference between the Chinese and the Han nationality in this study. The increase rate of P95 curve is faster than that of P75 and P40 curves. The incidence of hyperbilirubinemia in Han neonates was higher than that in Uygur newborns (蠂 ~ 2 / 71.523 / P0.01), the difference was statistically significant, preterm delivery, cesarean section, breast-feeding, Han nationality, milking time, Fetal stool excretion time is an independent risk factor for neonatal hyperbilirubinemia. Conclusion: the hourly bilirubin percentile curve reflects the trend of postnatal bilirubin level and has certain value in evaluating neonatal hyperbilirubinemia. The level of bilirubin in neonates of Uygur and Han nationality gradually increased with the increase of age, and the rate of increase of bilirubin in newborn infants of Han nationality was higher than that of newborns of Uygur nationality. The incidence of hyperbilirubinemia was also higher than that of Uygur newborns, preterm delivery, cesarean section, breastfeeding, Han nationality, milk opening time and fecal excretion time were independent risk factors of neonatal hyperbilirubinemia.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R722.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 丁國芳,張?zhí)K平,姚丹,徐景蓁,娜其,王華莊,李黎,楊琳,黃薇薇,王愚珍;我國部分地區(qū)新生兒黃疸的流行病學(xué)調(diào)查(英文)[J];Chinese Medical Journal;2001年04期

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本文編號：1526680