本文關(guān)鍵詞： 桑杏哮咳顆粒 CVA 燥邪犯肺型 臨床研究　出處：《云南中醫(yī)學(xué)院》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:本課題通過觀察桑杏哮咳顆粒治療小兒咳嗽變異性哮喘(CVA)發(fā)作期燥邪犯肺型的臨床療效,對該方治療小兒CVA的有效性進(jìn)行客觀、真實(shí)的評估,以期為該方藥的臨床應(yīng)用提供一定依據(jù),為小兒CVA的治療提供新的思路與方法。方法:本研究納入符合標(biāo)準(zhǔn)的患兒72例,用數(shù)字隨機(jī)分組法分為治療組桑杏哮咳顆粒組和對照組布地奈德氣霧劑組,研究過程中剔除12例,最終每組患兒有效病例各30例。分別對治療前后兩組患兒的主、次要癥狀積分及總癥狀積分進(jìn)行組內(nèi)、組間比較,綜合的評價桑杏哮咳顆粒的臨床療效。結(jié)果:1.總有效率治療組為90.00%,對照組為76.67%,經(jīng)比較,P0.05,有統(tǒng)計學(xué)差異,表明治療組總療效優(yōu)于對照組;2.治療前后兩組對改善咳嗽頻率、咳嗽性質(zhì)、咳嗽程度、咳痰、鼻干、唇干、咽干、飲食差、大便干方面比較,PO.05,有統(tǒng)計學(xué)差異,表明兩組對CVA的治療都是有效的;3.治療后兩組在改善咽干、飲食差、大便干方面,P0.01,有顯著性統(tǒng)計學(xué)差異,表明治療組在改善這三方面效果明顯優(yōu)于對照組;4.治療后兩組對咳痰的改善,PO.05,無統(tǒng)計學(xué)差異,表明兩組治療對咳痰的改善效果相當(dāng);5.對照組治療后咽干、飲食差積分和治療前比較,積分無下降,反而有所增加,PO.05,有統(tǒng)計學(xué)差異,表明對照組對咽干、飲食差情況改善不明顯;6.治療過程中60例患兒無明顯不良反應(yīng)。結(jié)論:通過對桑杏哮咳顆粒治療小兒CVA發(fā)作期燥邪犯肺型的臨床觀察,進(jìn)而對桑杏哮咳顆粒治療小兒燥邪犯肺型CVA發(fā)作期的臨床療效給予肯定,值得在臨床上應(yīng)用、推廣。
[Abstract]:Objective: to observe the clinical effect of Sangxingxingke granule on infantile cough variant asthma (CVA) during the attack period, and to evaluate the effectiveness of the prescription in treating children with CVA objectively and realistically. In order to provide a certain basis for the clinical application of the prescription, and to provide a new way of thinking and method for the treatment of CVA in children. Methods: 72 cases of children who met the criteria were included in this study. The treatment group and control group were randomly divided into two groups: the treatment group and the control group. 12 cases were excluded from the study, and 30 effective cases were found in each group. The two groups were divided into two groups before and after the treatment, respectively, before and after treatment, and 30 cases were treated with budesonide aerosol. The secondary symptom score and total symptom score were compared within the group, and comprehensive evaluation of the clinical efficacy of Sangxingxingke granule. Results: 1. The total effective rate was 90.00g in the treatment group and 76.67g in the control group. There was statistical difference between the two groups (P 0.05). The results showed that the total curative effect of the treatment group was better than that of the control group 2.There was statistical difference between the two groups in improving cough frequency, cough nature, degree of cough, expectoration, trunk of nose, dry lip, dry pharynx, poor diet and dry stool. The results showed that the treatment of CVA in both groups was effective. After treatment, there was a significant difference between the two groups in improving the pharyngeal dryness, poor diet and dry stool (P 0.01). The results showed that the improvement of expectoration in the treatment group was obviously better than that in the control group 4.After treatment, there was no statistical difference between the two groups in the improvement of expectoration, which indicated that the improvement effect of the two groups on expectoration was equivalent to that in the control group. The pharynx dry after treatment in the control group was better than that in the control group. Compared with before treatment, the score of dietetic difference was not decreased, but increased by PO.05. the difference was statistically significant, indicating that the control group had a positive effect on pharyngeal dryness. There were no obvious adverse reactions in 60 children during the course of treatment. Conclusion: the clinical observation of Sangxingxingke granule in treating the lung type of dryness evil in children with CVA attack. The clinical effect of Sangxingxingke granule on infantile dryness and evil invading lung type CVA is confirmed, which is worth applying and popularizing in clinic.
【學(xué)位授予單位】：云南中醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R272

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