本文關(guān)鍵詞： 癲癇 兒童 行為問題 臨床因素　出處：《大連醫(yī)科大學(xué)》2012年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：評估癲癇兒童的行為問題；分析不同臨床狀況下癲癇兒童的行為表現(xiàn)；探討影響癲癇兒童行為問題的臨床相關(guān)因素。 方法：收集癲癇兒童的一般資料和臨床資料(包括發(fā)作類型、發(fā)作頻率、起病年齡、病程及用藥數(shù)量)，同時采用父母用Achenbach兒童行為量表(CBCL)對84例癲癇兒童和61例正常兒童進(jìn)行行為評定。通過卡方檢驗、t檢驗比較兩組兒童一般情況、CBCL總分及各因子得分、異常行為問題發(fā)生率及不同性別癲癇兒童的行為表現(xiàn)。采用F檢驗比較病例組兒童不同發(fā)作類型、不同發(fā)作頻率和不同用藥數(shù)量的CBCL總分及各因子得分。采用單因素相關(guān)分析對癲癇兒童的臨床特征與CBCL總分及各因子得分進(jìn)行相關(guān)分析。運用多重線性回歸分析篩選影響癲癇兒童行為問題的臨床相關(guān)因素。 結(jié)果：①癲癇兒童異常行為問題發(fā)生率為35.71%，與對照組比較差異有明顯統(tǒng)計學(xué)意義（P0.01）。②兩組兒童CBCL比較結(jié)果：病例組在社會退縮、軀體主訴、焦慮/抑郁、社交問題、思維問題、注意問題、違紀(jì)問題、攻擊行為、內(nèi)向性、外向性行為問題得分及行為問題總分均高于對照組，差異有統(tǒng)計學(xué)意義（均P0.05）。③病例組男性違紀(jì)問題得分高于女性，差異有統(tǒng)計學(xué)意義（P0.05）。④不同臨床特征的病例組兒童CBCL比較結(jié)果：不同發(fā)作類型的三組注意問題、違紀(jì)行為、CBCL總分總體比較，差異有統(tǒng)計學(xué)意義(P0.05)；不同發(fā)作頻率的三組注意問題總體比較差異有統(tǒng)計學(xué)意義(P0.05)；不同用藥數(shù)量的三組軀體主訴、焦慮/抑郁、社交問題、CBCL總分總體比較，差異有統(tǒng)計學(xué)意義(P0.05)。⑤病例組CBCL與臨床特征的相關(guān)分析結(jié)果：發(fā)作頻率與注意問題、外向性問題正相關(guān)；起病年齡與焦慮/抑郁、社交問題、外向性問題、CBCL總分負(fù)相關(guān)；病程與軀體主訴、違紀(jì)問題、攻擊行為、內(nèi)向性問題、外向性問題、CBCL總分正相關(guān)。⑥多重線性回歸分析結(jié)果：病程和起病年齡是癲癇兒童行為問題的主要臨床影響因素，病程與CBCL總分正相關(guān)，，起病年齡與CBCL總分負(fù)相關(guān)。 結(jié)論：①癲癇兒童存在廣泛和明顯的行為問題，其中除男性在違紀(jì)問題高于女性外，其它方面均未見明顯的性別間差異。②癲癇的發(fā)作類型、發(fā)作頻率、病程、起病年齡、用藥數(shù)量等臨床特征與行為問題存在不同程度的相關(guān)性。③病程和起病年齡是癲癇兒童行為問題的主要臨床影響因素。
[Abstract]:Objective: to evaluate the behavioral problems of epileptic children, to analyze the behavior of epileptic children under different clinical conditions, and to explore the related clinical factors affecting the behavioral problems of epileptic children. Methods: the general and clinical data of epileptic children were collected, including the type of seizure, frequency of seizure, onset age, At the same time, 84 epileptic children and 61 normal children were assessed by parental Achenbach children behavior scale. The general situation of the two groups was compared by chi-square test and the total score of CBCL and the scores of each factor were compared by chi-square test. The incidence of abnormal behavior problems and the behavior of epileptic children of different genders. F test was used to compare the different seizure types of children in the case group. Single factor correlation analysis was used to analyze the clinical characteristics of epileptic children and the total score of CBCL and the scores of each factor. Multiple linear regression analysis was used to analyze the relationship between the clinical characteristics of epileptic children and the total score of CBCL and the scores of each factor. To screen the clinical related factors affecting behavioral problems in epileptic children. Results the incidence of abnormal behavior problems in children with epilepsy was 35.71%. There was significant difference in CBCL between the two groups. The results were as follows: social withdrawal, body complaints, anxiety / depression, social problems, thinking problems in the case group. The scores of attention problem, discipline violation problem, aggression behavior, introversion, extroversion behavior problem and the total score of behavior problem were higher than those of the control group, and the difference was statistically significant (P0.05.3). The difference was statistically significant (P 0.05). 4. The results of comparison of CBCL in children with different clinical characteristics were as follows: attention problem of three groups with different seizure types, total score of CBCL of violation of discipline, The difference was statistically significant (P 0.05); there were significant differences among the three groups with different seizure frequency (P 0.05); the total scores of body complaints, anxiety / depression, and social problems in the three groups with different dosage of drugs were compared as a whole. There was significant difference in the correlation between CBCL and clinical characteristics in patients with P0.055.The results showed that the frequency of onset was positively correlated with attention problems and extroverted problems, and the onset age was negatively correlated with anxiety / depression, social problems and extroverted problems. The course of disease was positively correlated with the total score of CBCL. The results showed that the course of disease and onset age were the main clinical influencing factors of behavioral problems in epileptic children. The course of disease was positively correlated with the total score of CBCL, and the onset age was negatively correlated with the total score of CBCL. Conclusion there are extensive and obvious behavioral problems in children with epilepsy at 1: 1. Except for the problem of violation of discipline in males and females, there is no significant gender difference in seizure type, frequency, course and age of onset of epilepsy. The clinical characteristics such as quantity of drugs and behavioral problems were related to different degrees. 3 the course of disease and age of onset were the main clinical influencing factors of behavioral problems in epileptic children.
【學(xué)位授予單位】：大連醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R742.1

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