發(fā)布時(shí)間：2018-02-10 18:12

  本文關(guān)鍵詞： 超聲心動(dòng)圖 縱向應(yīng)變 應(yīng)變率 斑點(diǎn)追蹤成像 兒童　出處：《重慶醫(yī)科大學(xué)》2017年碩士論文　論文類(lèi)型：學(xué)位論文

【摘要】：目的:應(yīng)用二維斑點(diǎn)追蹤成像技術(shù)定量分析健康兒童左室收縮期心肌縱向應(yīng)變及應(yīng)變率,并進(jìn)行不同年齡段正常參考值的初步分析。方法:對(duì)341例健康兒童超聲心動(dòng)圖進(jìn)行分析,按年齡分成6組,分別為新生兒組(0~28天,1組)22例;嬰兒組(㧐28天~㩳1歲,2組)54例;幼兒組(1~㩳3歲,3組)60例;學(xué)齡前組(3~㩳6歲,4組)81例;學(xué)齡組(6~㩳10歲,5組)62例;青春期組(10~㩳18歲,6組)62例。采用斑點(diǎn)追蹤軟件分析左心室心尖三個(gè)長(zhǎng)軸切面的動(dòng)態(tài)圖像,獲取左室收縮期18節(jié)段心肌縱向應(yīng)變及應(yīng)變率值和整體應(yīng)變值。結(jié)果:(1)同一室壁各節(jié)段間收縮期縱向應(yīng)變及應(yīng)變率的差異均有統(tǒng)計(jì)學(xué)意義(P0.05),且自基底段向心尖段呈逐漸增加趨勢(shì);(2)除后壁基底段和中間段外,余各室壁節(jié)段收縮期心肌縱向應(yīng)變(SL)規(guī)律為:SL(1組)SL(2組)SL(3、4、5組)SL(6組),且心肌整體縱向應(yīng)變?cè)谀挲g組間的趨勢(shì)與其一致;(3)18節(jié)段收縮期心肌縱向應(yīng)變與年齡呈正相關(guān),以側(cè)壁心尖段相關(guān)性最強(qiáng)(r=0.567,P0.01);與心率呈負(fù)相關(guān),以側(cè)壁中間段相關(guān)性最強(qiáng)(r=-0.529,P0.01);心肌整體縱向應(yīng)變與年齡呈正相關(guān)(r=0.681,P0.01),與心率呈負(fù)相關(guān)(r=-0.658,P0.01)。結(jié)論:初步分析了不同年齡段健康兒童左室收縮期心肌縱向應(yīng)變及應(yīng)變率的正常參考值,為臨床早期評(píng)價(jià)患兒左室局部心肌收縮功能異常和進(jìn)一步研究?jī)和募×W(xué)改變奠定基礎(chǔ)。
[Abstract]:Objective: to analyze the longitudinal strain and strain rate of left ventricular systolic myocardium in healthy children by two-dimensional speckle tracing imaging. Methods: 341 healthy children were analyzed by echocardiography and divided into 6 groups according to their age. 28 days? 54 cases in 1 year old group and 2 cases in infant group. 60 cases in 3 years old group and 30 cases in preschool group. 81 cases in 4 groups of 6 years old, 6 cases in school age group, 6 cases in school age group, 6 cases in school age group. 62 cases in 10 years old and 5 groups, 10 cases in puberty group, 10 cases in puberty group, 10 cases in puberty group. The dynamic images of three long axis sections of the left ventricular apex were analyzed by speckle tracing software in 62 patients (18 years old). The longitudinal strain and strain rate of 18 segments of left ventricular systolic phase and the global strain value were obtained. Results: there were significant differences in longitudinal strain and strain rate between different segments of the same ventricular wall (P 0.05), and from the basal segment to the apical segment, there were significant differences in the longitudinal strain and strain rate between the segments of the same ventricular wall. In addition to the base segment and the middle segment of the posterior wall, The rule of myocardial longitudinal strain (SLL) in the rest of ventricular wall segments was as follows: 1 / SL1 group / SL2 group and SL3 / 4 / 5 group and SL3 / 6 group, and the trend of global longitudinal strain of myocardium in age group was consistent with that of age group, and the longitudinal strain of 18 segments of systolic myocardium was positively correlated with age. In the apical segment of the lateral wall, the correlation was the strongest, and the correlation was negative with the heart rate, and the correlation between the apical segment of the lateral wall and the heart rate was negative. In the middle segment of the lateral wall, there was the strongest correlation between r-0.529 and P0.01, the longitudinal strain of myocardium was positively correlated with age, and negatively correlated with heart rate. Conclusion: the normal reference values of longitudinal strain and strain rate of left ventricular systolic phase in healthy children of different ages were preliminarily analyzed. It provides a basis for early clinical evaluation of left ventricular regional myocardial systolic dysfunction and further study of myocardial mechanical changes in children.
【學(xué)位授予單位】：重慶醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：R540.45

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本文編號(hào)：1501129