本文關(guān)鍵詞：加味玉屏風(fēng)飲治療小兒肺脾氣虛型反復(fù)呼吸道感染的臨床觀察　出處：《山西中醫(yī)學(xué)院》2014年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 兒童 反復(fù)呼吸道感染 肺脾氣虛型 臨床觀察

【摘要】：小兒反復(fù)呼吸道感染(RRTI)是兒科臨床常見病、多發(fā)病之一,因其經(jīng)常反復(fù)發(fā)作,纏綿難愈,嚴(yán)重影響小兒生活質(zhì)量,是兒科臨床面臨的較為棘手的病證。中醫(yī)藥治療手段溫和、療效確切,正在被越來越多的家長和患兒所接納。目的:觀察加味玉屏風(fēng)飲對肺脾氣虛型RRTI的臨床治療效果,并初步探討其作用機制。方法:收集符合各項條件的肺脾氣虛型小兒反復(fù)呼吸道感染患兒100例,所有病例均來自山西中醫(yī)學(xué)院第二中醫(yī)院兒科門診,病例采集時間從2012年10月到2013年3月,患兒年齡分布在1~14歲之間。將100例患兒按照就診順序隨機分成治療組和對照組,每組50例。治療組采取口服加味玉屏風(fēng)飲(黃芪、黨參、白術(shù)、防風(fēng)、茯苓、炙甘草組成),日一劑,水煎服,早晚分服,3個月為一個療程治療,對照組單純采用西安迪賽生物藥業(yè)有限責(zé)任公司生產(chǎn)的轉(zhuǎn)移因子口服液(每支10 ml),每次10 ml,每日1次,3個月為1個療程。主要觀察兩組的臨床療效以及實驗室檢測T細(xì)胞亞群和免疫球蛋白前后指標(biāo)變化。結(jié)果:100例患兒中96例患兒完成了整個研究過程,脫失、剔除病例4例。臨床觀察結(jié)果顯示,治療組的總有效率為95.83㳠,對照組總有效率為83.33㳠,其差異有統(tǒng)計學(xué)意義(P0.05)。用藥后治療組與對照組相比較,自汗、神疲乏力等中醫(yī)臨床癥狀非常顯著改善(P0.01),咳嗽、納差等中醫(yī)臨床癥狀明顯改善(P0.05),其差異有統(tǒng)計學(xué)意義。兩組患兒治療后各項指標(biāo)對照,治療組IgA、Ig G均有非常明顯改善,差異有統(tǒng)計學(xué)意義(P0.05)。兩組治療后對比,T細(xì)胞亞群指標(biāo)變化有統(tǒng)計學(xué)意義(P0.05),且治療組優(yōu)于對照組。結(jié)論:加味玉屏風(fēng)飲對肺脾氣虛型小兒反復(fù)呼吸道感染治療效果較好,能夠有效控制患兒呼吸道感染疾病的反復(fù)發(fā)作,減少發(fā)病次數(shù),延長發(fā)病間隔,降低發(fā)病等級,縮短疾病病程,并有效提高患兒體液免疫和細(xì)胞免疫水平,改善中醫(yī)臨床癥狀,且安全可靠,是治療肺脾氣虛型小兒反復(fù)呼吸道感染的有效方劑。
[Abstract]:Children with recurrent respiratory tract infection (RRTI) is a common disease in pediatrics, one of the frequent diseases, because of its recurrent attacks, lingering and difficult to heal, seriously affect the quality of life of children. It is a more intractable syndrome in pediatric clinic. Traditional Chinese medicine treatment is mild and effective. It is being accepted by more and more parents and children. Objective: to observe the clinical effect of Jiawei Yuping Fengyin on RRTI with deficiency of lung and spleen qi. Methods: 100 children with recurrent respiratory tract infection of lung and spleen qi deficiency type were collected. All cases were from the paediatric outpatient department of the second traditional Chinese Medicine Hospital of Shanxi College of traditional Chinese Medicine. Case collection time from October 2012 to March 2013, the age of the children between 1 and 14 years old. 100 children were randomly divided into treatment group and control group according to the order of visit. There were 50 cases in each group. The treatment group was treated with modified Yupingfeng decoction (Astragalus membranaceus, Codonopsis, Atractylodes macrocephala, Fangfeng, Poria cocos, Radix Glycyrrhiza officinalis, one dose per day, decoction of water, morning and evening, 3 months as a course of treatment). The control group was treated with the transfer factor oral liquid (10 ml / L, 10 ml / day) produced by Xi'an Desai Biopharmaceutical Co., Ltd. The clinical efficacy of the two groups and the changes of T cell subsets and immunoglobulin were observed before and after the laboratory examination. Results 96 out of 100 children were completed the whole study process. The clinical observation showed that the total effective rate of the treatment group was 95.83? , the total effective rate of control group was 83.33? The treatment group compared with the control group, self-sweating, fatigue and other TCM clinical symptoms were significantly improved P0.01, cough. The clinical symptoms of traditional Chinese medicine, such as anorexia, were obviously improved (P 0.05), and the difference was statistically significant. Compared with the control group, IgA Ig G in the treatment group was significantly improved. The difference was statistically significant (P 0.05). The changes of T cell subsets in the two groups were statistically significant (P 0.05). And the treatment group is better than the control group. Conclusion: modified Yuping Feng Yin has a better effect on recurrent respiratory tract infection in children with deficiency of lung and spleen qi. It can effectively control the recurrent attack of respiratory tract infection in children and reduce the incidence times. Prolonging the onset interval, reducing the grade of disease, shortening the course of disease, effectively improving the humoral and cellular immunity of children, improving the clinical symptoms of TCM, and safe and reliable. It is an effective prescription for recurrent respiratory tract infection in children with deficiency of lung and spleen qi.
【學(xué)位授予單位】：山西中醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R272

【參考文獻(xiàn)】

相關(guān)期刊論文 前3條

1 程淑一;;糖皮質(zhì)激素對小兒反復(fù)呼吸道感染的影響[J];臨床醫(yī)學(xué);2011年08期

2 謝靜;劉克麗;;觀音合劑治療小兒反復(fù)呼吸道感染52例臨床觀察[J];中醫(yī)藥導(dǎo)報;2009年04期

3 陳茵;中醫(yī)藥治療脾虛型小兒反復(fù)呼吸道感染136例[J];遼寧中醫(yī)雜志;2004年06期

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