兔斯氏艾美耳球蟲(chóng)感染模型的建立及病理學(xué)初步研究
[Abstract]:In order to provide a suitable animal model for the prevention and treatment of Eimeria skrjabini infection in rabbits, 16 New Zealand rabbits of the average age of .2 months were raised in a single cage. The oocysts of Eimeria skrjabini were collected from the naturally infected liver, and the sporulation of oocysts was cultured. The sporulated oocysts of 1.0 脳 105 / mL / mL oocysts were orally infused into New Zealand rabbits, and the infection model of Eimeria sibiricus was established. The liver and duodenum of New Zealand rabbits were observed and compared one month after infection. The results showed that there were obvious clinical symptoms in New Zealand rabbits after infection, which seriously restricted the growth and development of New Zealand rabbits. Morphological observation showed that the liver infection was serious, the surface was covered with white nodules, the bile in the gallbladder was thick and the color was golden, but the duodenum was not infected with coccidiosis, but also had obvious pathological changes. Pathological observation showed that there were a large number of Eimeria sterni in the liver and no coccidia in the duodenum, but the tissue structure was also destroyed, and the villi of the duodenum were seriously damaged. The results showed that the infection model of Eimeria sibiricus was successfully established in this experiment.
【作者單位】: 南通大學(xué)實(shí)驗(yàn)動(dòng)物中心;
【基金】:國(guó)家自然科學(xué)基金資助項(xiàng)目(31301926) 江蘇省自然科學(xué)基金資助項(xiàng)目(BK20130388)
【分類(lèi)號(hào)】:S858.291
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