本文選題：雞白痢 + 雞滑液囊支原體病��； 參考：《山東農(nóng)業(yè)大學(xué)》2015年碩士論文

【摘要】：近年來,山東省的種雞產(chǎn)業(yè)快速發(fā)展,但是規(guī)模不一、飼養(yǎng)管理和疫病防控水平不同,雞白痢和及滑液囊支原體病的感染率顯著不同。為了解雞白痢和滑液囊支原體病在山東省部分地區(qū)種雞場的流行情況,本文采用血清平板凝集試驗的方法,對濟寧、泰安、聊城和菏澤4個地區(qū)的13個種雞場的16312只父母代海蘭褐種雞進行了雞白痢沙門氏菌感染率的調(diào)查。對肥城和聊城2個地區(qū)的6個種雞場的2849只雞進行了雞滑液囊支原體的感染調(diào)查,并對其中的6個種公雞場進行了雞白痢沙門氏菌和滑液囊支原體共感染的情況調(diào)查。調(diào)查發(fā)現(xiàn),雞白痢的平均感染率為8.39%(1368/16312),公雞的感染率為9.32%(398/4270),母雞的感染率為8.06%(970/12042),90日齡以下的雞感染率為11%(206/1872),90日齡以上雞的感染率為8%(1160/14440)�；耗抑гw的平均感染率為16.71%(476/2849),公雞的感染率27.11%(398/1409),母雞的感染率為6.53%(94/1440),不同日齡雞只的感染率顯著不同,90日齡以下的雞感染率為7.26%(119/1640),90日齡以上的雞感染率為29.53%(357/1209)。兩病共感染率為0.91%(11/1209)。可見,山東省種雞場雞白痢和滑液囊支原體病普遍存在,個別場還比較嚴重,公雞和母雞都存在感染,青年雞、產(chǎn)蛋雞都不同程度的受到雞白痢沙門氏菌和雞滑液囊支原體的感染,兩垂直傳染性疾病的凈化勢在必行。采集雞白痢和滑液囊支原體病血清陽性的消瘦、精神萎靡的雞只進行了剖檢診斷和病理組織學(xué)的檢查,雞白痢以肝臟壞死灶、脾臟腫大和多器官白痢結(jié)節(jié)為病變特征,結(jié)節(jié)以巨噬細胞、淋巴細胞、異嗜性粒細胞及成纖維細胞為主�；耗抑гw病則以跗關(guān)節(jié)、趾關(guān)節(jié)及胸部滑膜囊腫脹,腔內(nèi)充滿膠胨樣滲出物,鏡檢滑膜囊、關(guān)節(jié)腔和腱鞘中可見大量炎性細胞和纖維素滲出,滑液囊膜增厚及絨毛樣增生,其中見大量淋巴細胞和巨噬細胞浸潤、增生。對分離到的10株沙門氏菌進行了7種藥物的敏感性實驗,結(jié)果顯示對氟苯尼考的耐藥率最高,達到60%,其次是卡那霉素,達50%,對左旋氧氟沙星的敏感性最高,達到80%,三重耐藥菌的比例最高達30%,兩重和四重耐藥的比例均為20%。細菌多重耐藥性的產(chǎn)生給臨床藥物防治帶來了極大的困難。
[Abstract]:In recent years, the breeding chicken industry in Shandong Province has developed rapidly, but the scale is different. The infection rate of chicken white dysentery and mycoplasma synovial sac is significantly different with different levels of breeding management and epidemic disease prevention and control. In order to understand the epidemic situation of chicken white dysentery and mycoplasma synovial sac disease in some areas of Shandong Province, serum plate agglutination test was used to study the prevalence of Jining and Tai'an. The infection rate of Salmonella pullorum was investigated in 16312 parents of 13 chicken farms in Liaocheng and Heze. The infection of mycoplasma synovial sac in 2849 chickens from 6 breeding farms in Feicheng and Liaocheng was investigated, and the co-infection of Salmonella pullorum and Mycoplasma synoviae in 6 male farms were investigated. The results showed that the average infection rate of white dysentery was 8.39% (1368 / 16312), the infection rate of cock was 9.32% (398 / 4270), the infection rate of hen was 8.06% (970 / 12042), the infection rate of chickens under 90 days old was 11% (206 / 1872), the infection rate of chickens over 90 days old was 8% (1160 / 14440). The average infection rate of mycoplasma synovial sac was 16.71% (476 / 2849), the infection rate of cock was 27.11% (398 / 1409), the infection rate of hen was 6.53% (94 / 1440). The total infection rate of the two diseases was 0.91% (11 / 1209). It can be seen that white dysentery and mycoplasmosis of synovial sac are prevalent in chicken farms in Shandong Province, and are relatively serious in individual farms. Both roosters and hens are infected. Young chickens, Laying hens were infected by Salmonella pullorum and Mycoplasma synovium in varying degrees, so purification of two vertical infectious diseases was imperative. Chicken white dysentery and mycoplasma synovial sac mycoplasmal seropositive emaciation were collected for dissection diagnosis and histopathological examination. The disease was characterized by liver necrosis, splenomegaly and multiple organ pullorum nodule. The nodules were mainly macrophages, lymphocytes, heterophil and fibroblasts. Mycoplasmosis of synovial sac was caused by swelling of tarsal joint, toe joint and thoracic synovial cyst, filling the cavity with peptone exudate. A large number of inflammatory cells and cellulose exudates were observed under microscope in synovial sac, articular cavity and tendon sheath, synovial capsule thickening and villous hyperplasia. Among them, a large number of lymphocytes and macrophages infiltration, proliferation. The sensitivity tests of 7 kinds of drugs to 10 Salmonella strains were carried out. The results showed that the drug resistance rate to florfenicol was the highest (60%), followed by kanamycin (50%) and levofloxacin (50%). Up to 80%, the proportion of triple resistant bacteria reached 30%, and the ratio of double and quadruple drug resistance was 20. 5%. The emergence of multidrug resistance of bacteria brings great difficulties to the prevention and treatment of clinical drugs.
【學(xué)位授予單位】：山東農(nóng)業(yè)大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：S858.31

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