發(fā)布時(shí)間：2018-03-04 19:44

  本文選題：雞蛔蟲　切入點(diǎn)：潮霉素B　出處：《中國獸藥雜志》2017年01期 　論文類型：期刊論文

【摘要】：為了解潮霉素B預(yù)混劑臨床驅(qū)除絳蟲線蟲的有效性和給藥時(shí)間的合理性,依據(jù)獸藥臨床試驗(yàn)規(guī)范,試驗(yàn)選擇了蠕蟲自然感染皖西麻黃雞824只,按要求隨機(jī)分為3組,分別為潮霉素B預(yù)混劑治療組284只,芬苯噠唑粉對(duì)照藥物組284只,不治療的感染對(duì)照組256只,試驗(yàn)周期根據(jù)臨床治療效果確定。結(jié)果顯示,潮霉素B預(yù)混劑,推薦劑量10 mg/kg混飼,連續(xù)飼喂21 d,對(duì)雞蛔蟲和絳蟲的粗計(jì)驅(qū)蟲率分別為63%和26%,表現(xiàn)明顯的驅(qū)除蛔蟲作用(P0.05),連續(xù)飼喂42 d,對(duì)雞蛔蟲和絳蟲的粗計(jì)驅(qū)蟲率分別為100%和-13%,驅(qū)蛔蟲效果極顯著(P0.01);對(duì)照藥物芬苯噠唑粉,50 mg/kg混飼,連續(xù)飼喂6 d,對(duì)雞蛔蟲和絳蟲的粗計(jì)驅(qū)蟲率分別為100%和44%,同樣具有極顯著的驅(qū)除蛔蟲作用(P0.01),本試驗(yàn)中2種藥物的驅(qū)蛔蟲效果相當(dāng),對(duì)絳蟲的驅(qū)除作用不明顯(P0.05)。潮霉素B預(yù)混劑10 mg/kg混飼,連續(xù)飼喂42 d,可以驅(qū)凈雞蛔蟲的感染,但對(duì)雞絳蟲感染無明顯的驅(qū)除作用。
[Abstract]:In order to understand the effectiveness of hygromycin B premixed agent in the clinical elimination of tapeworm nematodes and the reasonableness of the time of administration, according to the standard of veterinary medicine clinical trial, 824 chickens infected naturally by worms were selected and randomly divided into 3 groups according to the requirements. There were 284 rats in the hygromycin B premixture group, 284 in the fenbendazole powder control group and 256 in the untreated infection control group. The experimental period was determined according to the effect of clinical treatment. The recommended dose was 10 mg/kg. After continuous feeding for 21 days, the crude insecticidal rates of Ascaris lumbricoides and tapeworm were 63% and 26, respectively, which showed obvious action of eliminating Ascaris lumbricoides (P0.05N). After continuous feeding for 42 days, the rates of crude worm repellent to Ascaris and tapeworm were 100% and -13, respectively. The control group was fed with fenbendazole powder for 50 mg/kg. After 6 days of continuous feeding, the crude insecticidal rates of Ascaris and tapeworm were 100% and 44, respectively, and they also had a very significant effect of eliminating Ascaris lumbricoides (P0.01G). The two drugs had the same effect on the drive of Ascaris lumbricoides in this experiment. Hygromycin B premixed feed for 10 mg/kg, fed continuously for 42 days, could drive off the infection of Ascaris lumbricoides, but had no obvious effect on the infection of tapeworm.
【作者單位】： 中國農(nóng)業(yè)科學(xué)院上海獸醫(yī)研究所;安徽省農(nóng)業(yè)科學(xué)院畜牧獸醫(yī)研究所;浙江海正藥業(yè)有限公司;
【基金】：國家重點(diǎn)研發(fā)計(jì)劃專項(xiàng)(2016YFD0501303) 國家自然科學(xué)基金項(xiàng)目(31272607)
【分類號(hào)】：S858.31

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