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  本文選題：乙型腦炎病毒 + 黃熱病病毒��； 參考：《第一軍醫(yī)大學(xué)》2005年碩士論文

【摘要】：乙型腦炎是由乙型腦炎病毒(JEV)引起,經(jīng)蚊蟲叮咬傳播的一種傳染性疾病。該病能引起嚴(yán)重的腦炎,往往會導(dǎo)致永久性的大腦損傷,且死亡率高。全球大概每年有35,000-50,000例乙型腦炎患者,該病主要分布于亞洲地區(qū)。 黃熱病由黃熱病病毒(YFV)引起,曾在南美洲、非洲等熱帶地區(qū)引起大范圍的流行,每年估計有200,000例黃熱病患者(30,0001例死亡)。 JEV與YFV同屬于黃病毒屬,病程早期對疾病診斷都有一定困難。由于目前尚無有效手段阻止或延緩病程發(fā)展,因此早期實驗室檢測(JEV/YFV)對于迅速做出診斷,確立正確的治療方案、避免誤診、貽誤病程有重要意義。 傳統(tǒng)的實驗室診斷方法往往依賴于免疫學(xué)方法檢測病毒抗原。由于JEV、YFV與其它黃病毒之間會產(chǎn)生血清學(xué)交叉反應(yīng),所以傳統(tǒng)的診斷方法容易產(chǎn)生假陽性結(jié)果�；赗T-PCR技術(shù)的分析方法也被應(yīng)用于檢測JEV、YFV,但也無法避免假陽性和假陰性結(jié)果的產(chǎn)生。
[Abstract]:Encephalitis B is a contagious disease caused by Japanese encephalitis virus (JEV), which is transmitted by mosquito bites. It can cause severe encephalitis and often lead to permanent brain damage and high mortality. There are about 35000-50000 cases of encephalitis a year around the world. The disease is mainly distributed in Asia.
Yellow fever, caused by the yellow fever virus (YFV), has caused widespread prevalence in tropical regions such as South America and Africa. It is estimated that 200000 cases of yellow fever (300001 deaths) are estimated each year.
JEV and YFV belong to the genus yellows. It is difficult to diagnose the disease early in the course of the disease. Because there is no effective means to prevent or delay the development of the disease, early laboratory testing (JEV/YFV) is of great significance for the rapid diagnosis, the establishment of the correct treatment scheme, and the avoidance of misdiagnosis.
Traditional laboratory diagnosis methods often rely on immunological methods to detect virus antigens. Because of the serological cross reaction between JEV, YFV and other yellow viruses, the traditional diagnostic methods easily produce false positive results. The analysis method based on RT-PCR technology is also used to detect JEV and YFV, but it can not avoid false positive and false positives. The emergence of negative results.
【學(xué)位授予單位】：第一軍醫(yī)大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2005
【分類號】：R346

【引證文獻(xiàn)】

相關(guān)期刊論文 前1條

1 譚翰清;陳華;譚海芳;;乙型腦炎病毒檢測技術(shù)研究進(jìn)展[J];中國衛(wèi)生檢驗雜志;2006年11期

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本文編號：2102707