本文選題：心理社會應(yīng)激 + sFas　； 參考：《浙江大學(xué)》2007年碩士論文

【摘要】： [目的]：探討個(gè)體心理社會應(yīng)激與血清可溶性Fas(sFas)、FasL水平的相關(guān)性。 [對象和方法]：1．研究對象：分為老年組和青年組，每組50人；老年組為某療養(yǎng)院住院體檢療養(yǎng)老人，平均年齡為77.9±4.3歲；青年組均為健康青年志愿者，平均年齡為26.3±5.0歲。2．研究工具：(1)自編個(gè)人基本情況調(diào)查量表；(2)簡易應(yīng)對方式問卷(SCSQ)：(3)領(lǐng)悟社會支持量表(PSSS)；(4)中文版知覺心理壓力量表(CPSS)；(5)癥狀自評量表(SCL90)；(6)血清sFas／FaSL濃度測定試劑盒。3．研究方法：在統(tǒng)一指導(dǎo)語的條件下，研究對象一次性完成調(diào)查問卷的填寫。于完成問卷的同一天清晨抽取研究對象空腹靜脈血2ml，離心后收集血清，測定血清sFas／FasL的濃度。血清sFas／FasL濃度測定采用雙抗體夾心法(ELISA)。用SPSS13.0統(tǒng)計(jì)軟件對實(shí)驗(yàn)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)分析。統(tǒng)計(jì)分析包括青年組與老年組知覺心理壓力、應(yīng)對方式、領(lǐng)悟社會支持測試結(jié)果比較；青年組與老年組血清sFas／FasL水平比較：分別對青年組和老年組的知覺心理壓力、應(yīng)對方式、領(lǐng)悟社會支持與血清sFas／FasL水平進(jìn)行相關(guān)性性分析；老年組SCL90高分組與SCL90低分組sFas／FasL水平差異分析；老年組SCL90總分、積極應(yīng)對總分與sFas／FasL水平相關(guān)分析及逐步回歸分析。 [結(jié)果]：青年組較老年組知覺心理壓力水平高：老年組血清sFas濃度比青年組高，，血清FasL濃度比青年組低；青年組心理社會應(yīng)激相關(guān)因素與血清sFas／FasL水平?jīng)]有顯著相關(guān)性：老年組心理社會應(yīng)激水平與血清sFas水平顯著正相關(guān)，積極應(yīng)對方式與血清sFas水平顯著負(fù)相關(guān)。 [結(jié)論]：個(gè)體心理社會應(yīng)激水平以及血清sFas／FasL水平與年齡因素有關(guān)，老年人的心理社會應(yīng)激水平、應(yīng)對方式與血清sFas水平具有顯著相關(guān)性。
[Abstract]:Objective: to investigate the correlation between individual psycho-social stress and the level of serum soluble FassFas-FasL. [objects and methods]: 1. The subjects were divided into elderly group and young group with 50 persons in each group, the elderly group was inpatients with physical examination in a sanatorium with an average age of 77.9 鹵4.3 years, and the young group were all healthy young volunteers with an average age of 26.3 鹵5.0 years. Research tool: 1) Self-designed personal basic situation Survey scale / 2) A simple coping style questionnaire: SCSSS: 3) perceived Social support scale (PSSS5) symptom Checklist (SCL 90 / 6) Serum sFas/FaSL concentration Test Kit. 3. Methods: under the condition of unified instruction, the subjects completed the questionnaire in one-time. Fasting venous blood was drawn from the subjects in the morning of the same day. Serum was collected after centrifugation to determine the concentration of serum sFas/FasL. Serum sFas/FasL concentration was determined by double antibody sandwich method. The experimental data were analyzed by SPSS13.0 software. The statistical analysis included the comparison of perceived psychological pressure, coping style and perceived social support test results between the young group and the old group, the comparison of serum sFas/FasL level between the young group and the old group: the perceived psychological pressure and coping style of the young group and the old group, respectively. The relationship between perceived social support and serum sFas/FasL level; the difference of sFas/FasL level between the high score group of SCL90 and the low group of SCL90 in the elderly group; the total score of SCL90 in the elderly group; the correlation analysis of the total score of coping with the level of sFas/FasL and stepwise regression analysis. [results]: the level of perceptual psychological pressure in the young group was higher than that in the old group: the serum sFas concentration in the elderly group was higher than that in the young group, and the serum FasL concentration was lower than that in the young group. There was no significant correlation between psychosocial stress and serum sFas/FasL level in young group. There was a significant positive correlation between psychosocial stress level and serum sFas level in elderly group, and negative correlation between positive coping style and serum sFas level. Conclusion: the level of individual psycho-social stress and serum sFas/FasL level are related to age factors. The level of psycho-social stress and coping style are significantly correlated with serum sFas level in the elderly.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2007
【分類號】：R395

【引證文獻(xiàn)】

相關(guān)期刊論文 前1條

1 李菁;李春文;;護(hù)理干預(yù)對腦卒中患者配偶心理健康水平影響的研究進(jìn)展[J];吉林醫(yī)學(xué);2011年28期

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