【摘要】：目的:與西藥治療作對(duì)照,運(yùn)用中藥安神寧動(dòng)顆粒治療兒童多動(dòng)癥之肝腎陰虛證,以期從中醫(yī)角度分析兒童多動(dòng)癥,觀察及分析安神寧動(dòng)顆粒治療本病的臨床療效。方法:按照隨機(jī)、對(duì)照的原則,60例患兒符合納入標(biāo)準(zhǔn),隨機(jī)分為兩組,即中藥組、西藥對(duì)照組,各30例。兩組均進(jìn)行6周的系統(tǒng)治療。治療前以及治療之后分別對(duì)三大常規(guī)、肝腎功能以及心電圖做一次檢測(cè),評(píng)估安全性,若有不良事件發(fā)生,則分析處理。6周后對(duì)總療效及主要癥狀(注意力渙散、多動(dòng)沖動(dòng))改善情況進(jìn)行對(duì)比。對(duì)發(fā)生的不良事件做相關(guān)記錄。結(jié)果:1.治療組總有效率86.7%,對(duì)照組83.3%,經(jīng)秩和檢驗(yàn),P0.05,差異無統(tǒng)計(jì)學(xué)意義。2.治療組和對(duì)照組治療多動(dòng)癥之注意力渙散癥狀積分組內(nèi)比較,經(jīng)t檢驗(yàn),兩者均P0.01,差異有高度統(tǒng)計(jì)學(xué)意義。兩組組間進(jìn)一步比較,P0.05,差異無統(tǒng)計(jì)學(xué)意義。3.治療組和對(duì)照組治療多動(dòng)癥之多動(dòng)、沖動(dòng)癥狀積分組內(nèi)比較,經(jīng)t檢驗(yàn),兩者均P0.01,差異有高度統(tǒng)計(jì)學(xué)意義。兩組組間進(jìn)一步比較,P0.05,差異具有統(tǒng)計(jì)學(xué)意義。4.兩組在治療過程中都未曾出現(xiàn)不良的副反應(yīng)。結(jié)論:1.中藥組、對(duì)照組治療本病的總療效相當(dāng);2.中藥組在改善多動(dòng)、沖動(dòng)癥狀方面優(yōu)于對(duì)照組。3.安神寧動(dòng)顆粒治療兒童多動(dòng)癥肝腎陰虛證有效,尤其可改善兒童多動(dòng)癥多動(dòng)、沖動(dòng)癥狀。
[Abstract]:Objective: to observe and analyze the clinical effect of Anshenning action granule in treating children's hyperactivity syndrome (ADHD) from the point of view of traditional Chinese medicine (TCM) by using Anshenning granule to treat the syndrome of deficiency of liver and kidney yin in children with hyperactivity syndrome (ADHD). Methods: according to the principle of randomization and control, 60 children were randomly divided into two groups: the traditional Chinese medicine group and the western medicine control group, each with 30 cases. Both groups were treated systematically for 6 weeks. Before and after treatment, the three major routine, liver and kidney function and electrocardiogram were tested to evaluate the safety, and if there were adverse events, the treatment was analyzed and dealt with. Hyperactive impulse) improvement is compared. Record adverse events. Results: 1. The total effective rate of the treatment group was 86.7%, while that of the control group was 83.3%. By rank sum test, the difference was not statistically significant (P 0.05). There was a significant difference between the treatment group and the control group in the score of attention deficit disorder (ADHD). By t test, the difference was statistically significant between the two groups (P0.01). Further comparison between the two groups, P0.05, the difference was not statistically significant. The scores of hyperactivity and impulsive symptoms in the treatment group and the control group were compared with each other by t test (P 0.01), the difference was statistically significant. Further comparison between the two groups, P0.05, the difference was statistically significant. There were no adverse reactions in both groups during the course of treatment. Conclusion: 1. Chinese medicine group, control group, the total efficacy of the treatment of this disease is similar; 2. Chinese medicine group in improving hyperactivity, impulse symptoms than the control group. 3. 3. Anshenning granule is effective in treating children with hyperactivity syndrome of liver and kidney yin deficiency, especially in improving hyperactivity and impulsive symptoms in children with ADHD.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R277.7

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