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藥罐療法對腹型肥胖人群內臟脂肪代謝影響的臨床研究

發(fā)布時間:2018-06-26 02:11

  本文選題:腹型肥胖 + 腹部脂肪厚度。 參考:《北京中醫(yī)藥大學》2017年碩士論文


【摘要】:腹型肥胖又稱"中心性肥胖"(或內臟型肥胖)是指脂肪過多的沉積在腹部或腹腔內臟。大量研究發(fā)現(xiàn),腹型肥胖是2型糖尿病、高血壓、高脂血癥、脂肪肝等慢性病的危險因素。近年來腹型肥胖的人群越來越多,因此制定出有效的防治方案已經(jīng)到了刻不容緩的地步。1研究目的本研究通過觀察藥罐療法對腹型肥胖人群內臟脂肪代謝的臨床療效,探討藥罐療法對腹型肥胖人群內臟脂肪代謝的影響及作用機理,為藥罐療法對腹型肥胖人群內臟脂肪代謝的有效性提供依據(jù)。2研究方法在2016年8月-2017年1月于北京中醫(yī)藥大學東方醫(yī)院針灸科門診就診的患者中,選用符合入組標準的60例腹型肥胖受試者,并采取隨機數(shù)字表法,隨機分為治療組30例,對照組30例。治療組采用藥罐療法,一周治療2次,整個療程為8周,治療期間要求受試者少食多餐,禁食油膩,多運動;對照組采用空白等待觀察,對受試者不進行治療,觀察期間要求受試者少食多餐,禁食油膩,多運動,觀察期8周結束后,可根據(jù)受試者的要求給予藥罐補償性治療。研究者分別于治療前后測量記錄兩組的各項指標,并運用統(tǒng)計軟件SPSS20.0進行數(shù)據(jù)統(tǒng)計分析。3研究結果在本研究收入的60例受試者中,脫落與剔除者共6例,最終完成54例,其中治療組27例,對照組27例。3.1腹部脂肪厚度及UVI比較藥罐療法組經(jīng)治療腹部皮下脂肪厚度(S1、S2)、內臟脂肪厚度(V1、V2)、左肝前脂肪厚度(AHF)、右腎周脂肪囊厚度(PRF)較治療前有所下降,具有統(tǒng)計學意義(p0.05),內臟脂肪指數(shù)(UVI)治療前后無明顯差別(p0.05);空白等待觀察組腹部脂肪厚度S1、V1、S2、V2、AHF、PRF及UVI觀察前后無明顯差異(p0.05);藥罐療法組治療后與空白等待觀察組觀察后S1、V1、S2、V2、AHF、PRF具有明顯差異(p0.05),UVI 無明顯差異(p0.05)。治療組 S1、V1、S2、V2、AHF、PRF 治療前后差值與對照組觀察前后差值比較具有顯著性差別,具有統(tǒng)計學意義(p0.05),UVI差值無明顯差異(p0.05)。3.2血清內脂素比較藥罐療法組血清內脂素治療后較治療前下降,具有統(tǒng)計學意義(P<0.05);空白等待觀察組血清內脂素觀察前后無明顯差異(p0.05);藥罐療法組治療后與空白等待觀察組觀察后血清內脂素具有明顯差異(p0.05)。治療組血清內脂素治療前后差值與對照組觀察前后差值比較具有顯著性差別,具有統(tǒng)計學意義(p0.05)。3.3簡易體脂參數(shù)比較藥罐療法組經(jīng)治療體重(BW)、腰圍(WC)、臀圍(HC)、腰臀比(WHR)、體重指數(shù)(BMI)均比治療前有所下降(p0.05);空白等待觀察組BW、WC、BMI、WHR觀察后數(shù)值增加,具有統(tǒng)計學意義(p0.05),HC觀察前后無明顯差異(p0.05);治療組治療后與對照組觀察后HC、BMI有明顯差別(p0.05),BW、WC、WHR無明顯差異(p0.05),治療組BW、WC、HC、WHR、BMI治療前后差值與對照組觀察前后差值比較具有顯著性差別,具有統(tǒng)計學意義(p0.05)。3.4有效率比較經(jīng)治療,藥罐療法組受試者0例治愈,4例顯效,20例有效,總有效率為88.9%,空白等待觀察組受試者0例治愈,0例顯效,8例有效,總有效率為29.6%,將兩組的有效率進行比較,p0.05,兩者具有顯著性差別。4結論通過對這54例腹型肥胖受試者的臨床研究發(fā)現(xiàn),藥罐療法對改善腹型肥胖人群的內臟脂肪代謝具有良好的療效。通過兩組間的有效率比較,兩組間的差異顯著,提示藥罐療法是治療腹型肥胖的一種安全有效的方法,臨床可以加以推廣使用。
[Abstract]:Abdominal obesity, also known as "central obesity" (or visceral obesity) refers to the deposition of fat in the abdomen or abdominal viscera. A large number of studies have found that abdominal obesity is a risk factor for chronic diseases such as type 2 diabetes, hypertension, hyperlipidemia, fatty liver and so on. In recent years, more and more people with abdominal obesity have developed effective prevention and control schemes. The objective of this study is to explore the effect of drug cupping therapy on visceral fat metabolism in obese people of abdominal type by observing the clinical effect of drug cupping therapy on visceral fat metabolism in obese people of abdominal type, and to explore the effect of drug can therapy on visceral fat metabolism in obese people of abdominal type, and to provide the basis for the study of.1..2 research In August 2016 -2017 years -2017 years in January in the Department of acupuncture and moxibustion at the Eastern Hospital of Beijing University of Chinese Medicine, the patients who were treated in the Department of acupuncture and moxibustion Department of the Eastern Hospital of Beijing University of Chinese Medicine were selected and randomly divided into 30 cases in the treatment group and 30 cases in the control group. The treatment group was treated with drug tank therapy, 2 times a week, and the whole course of treatment was 8 weeks. During the period of treatment, the subjects were required to eat less meal, fasting greasy and more exercise. The control group was not treated with a blank wait for observation. During the observation period, the subjects were asked to eat less meals, fasting and exercise more. After 8 weeks of observation, the patients could be treated according to the requirements of the subjects. The researchers were measured before and after the treatment. The indexes of two groups were recorded, and statistical software SPSS20.0 was used to analyze the results of data statistics and analysis (.3). Among the 60 subjects of this study, 6 cases were lost and eliminated, and 54 cases were finished. 27 cases in the treatment group and 27 cases of.3.1 in the control group were treated with the thickness of abdominal fat and the thickness of the abdominal subcutaneous fat (S1, compared with the UVI ratio. S2), the thickness of visceral fat (V1, V2), the thickness of the left prehepatic fat (AHF), the thickness of the right pericenal fat sac (PRF) was lower than that before the treatment (P0.05), and there was no significant difference (P0.05) before and after the treatment of visceral adipose index (UVI), and there was no significant difference between before and after the observation of the abdominal fat thickness in the blank waiting group. There were significant differences in S1, V1, S2, V2, AHF, PRF after the observation group was observed in the drug tank therapy group after the observation group was waiting for the observation group, and there was no significant difference in UVI (P0.05). The difference value before and after the treatment of the treatment group was significantly different from that of the control group before and after the observation. There was a significant difference between the difference values before and after the observation of the treatment group. Serum endogenous lipoprotein compared with the treatment group, serum endogenous lipoprotein was lower than before treatment, and had statistical significance (P < 0.05). There was no significant difference between before and after the observation of serum endogenous lipoprotein (P0.05) in the blank waiting group (P0.05) after the treatment group was treated with blank wait observation group (P0.05). The difference between before and after the treatment was significantly different from that of the control group before and after observation. The difference was statistically significant (P0.05).3.3 simple body fat parameters compared with the body weight (BW), waist circumference (WC), hip circumference (HC), waist to hip ratio (WHR), and body mass index (BMI) decreased (P0.05) compared with before treatment (P0.05); blank wait for observation group BW, WC, BMI, WHR view After observation, there was statistical significance (P0.05), and there was no significant difference between before and after HC observation (P0.05), and after the treatment group was treated with HC, BMI had significant difference (P0.05), BW, WC, WHR had no significant difference (P0.05). The difference value before and after treatment was significantly different from that of the control group before and after the treatment. Learning meaning (P0.05).3.4 was effective. 0 cases were cured, 4 cases were cured, 20 cases were effective, 20 cases were effective, the total effective rate was 88.9%. The blank waiting for the observation group was cured in 0 cases, 0 cases were cured, 8 cases were effective, the total effective rate was 29.6%, and the effective rate of the two groups was compared, P0.05, the significant difference.4 conclusion through this 54 The clinical study of abdominal obesity subjects found that drug cupping therapy has a good effect on improving visceral fat metabolism in abdominal obesity. Compared with the efficiency of the two groups, the difference between the two groups is significant, suggesting that the drug cupping therapy is a safe and effective method for the treatment of abdominal obesity and can be used in clinical practice.
【學位授予單位】:北京中醫(yī)藥大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R244.3

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