本文選題：助孕散 + 穴位敷貼　； 參考：《廣州中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的通過觀察穴位敷貼結(jié)合助孕散治療多囊卵巢綜合征不孕的臨床療效,從而為臨床穴位敷貼結(jié)合助孕散治療多囊卵巢綜合征不孕提供真實可靠的依據(jù),客觀評價穴位敷貼結(jié)合助孕散的臨床應(yīng)用價值。方法采用完全隨機法將納入研究的68名合格受試者隨機分為治療組:穴位敷貼+助孕散內(nèi)服組(A組);對照組:單純助孕散內(nèi)服組(B組)。A組每日一劑,月經(jīng)期停止服藥,穴位敷貼方法:月經(jīng)干凈后第三天開始敷藥,每天一次,至月經(jīng)來潮停止,三個月為一療程,共四個療程,若懷孕則停止治療。B組中藥服用方法同A組,三個月為一療程,共觀察四個療程,若懷孕則停止治療。兩組的年齡、病程、備孕時間、治療前生殖內(nèi)分泌指標(biāo)研究分析,差異無統(tǒng)計學(xué)意義(P0.05),具有可比性。每月檢測排卵一次,分別記錄治療前和治療后患者B超監(jiān)測卵泡與排卵情況、妊娠情況、內(nèi)分泌激素測定數(shù)據(jù)整理并進行統(tǒng)計分析。結(jié)果1.排卵率情況A組患者共治療200個周期,恢復(fù)排卵周期有111個,排卵率55.43%;B組共治療284個周期,排卵周期有93個,排卵率32.73%。A組與B組治療后組間比較,A組治療后較B組治療后有顯著差異(P=0.0000.05),A組排卵率高于B組。2.妊娠率情況A組治療后妊娠21例,未妊娠10例,妊娠率67.74%;B組治療后妊娠17例,未妊娠14例,妊娠率54.84%。A組與B組治療后組間比較,A組和B組治療后妊娠率無統(tǒng)計學(xué)意義P=0.297(P0.05),但對治療周期進行統(tǒng)計分析發(fā)現(xiàn),A組的治療周期明顯小于B組,差異有統(tǒng)計學(xué)意義P=0.004(P0.05)3.睪酮情況分別對兩組治療前后T進行組內(nèi)統(tǒng)計分析,A組與B組T指標(biāo)治療前后比較,差異具有統(tǒng)計學(xué)意義PA=0.00、PB=0.023(P0.05)。分別對兩組治療后T指標(biāo)進行組間統(tǒng)計分析,差異具有統(tǒng)計學(xué)意義P=0.007(P0.05),對兩組治療前后T指標(biāo)差值進行統(tǒng)計分析,A組與B組比較差異具有統(tǒng)計學(xué)意義P=0.004(P0.05)。研究結(jié)果表明,A、B兩組都能降低患者T指標(biāo)水平,但是A組對于T指標(biāo)血液中的水平改善情況比B組好。4.LH/FSH 情況分別對兩組治療前后LH/FSH進行組內(nèi)統(tǒng)計分析,A、B兩組治療前后比較,差異具有統(tǒng)計學(xué)意義PA=0.00、PB=0.013(P0.05),分別對兩組治療后LH/FSH比值進行組間統(tǒng)計分析,差異具有統(tǒng)計學(xué)意義P=0.000(P0.05),對兩組治療前后LH/FSH比值差值進行統(tǒng)計分析,A組與B組比較差異具有統(tǒng)計學(xué)意義P=0.000(P0.05)。數(shù)據(jù)表明A、B兩組均能明顯降低患者LH/FSH比值水平,對于LH/FSH比值水平的改善,A組優(yōu)于B組。結(jié)論(1)兩組均能改善患者排卵情況,且A組優(yōu)于B組。同時,兩組能提高妊娠率,A、B兩組在治療后妊娠情況相當(dāng),但是A組能明顯縮短治療周期。(2)兩組均能明顯降低患者血液中T指標(biāo)水平情況,對于T指標(biāo)水平的改善,A組療效優(yōu)于B組。(3)兩組均能明顯降低患者LH/FSH水平,對于LH/FSH水平的改善,A組優(yōu)于B組。
[Abstract]:Objective to observe the clinical efficacy of acupoint application combined with Zhuyong powder in the treatment of infertility with polycystic ovary syndrome (PCOS), so as to provide a true and reliable basis for the treatment of polycystic ovary syndrome infertility. Objective to evaluate the clinical application value of acupoint application combined with Zhuyong powder. Methods A total of 68 eligible subjects were randomly divided into treatment group (group A) and control group (group A), group B (group B), group A (group A), group A (group A) and group A (group A). Acupoint application: the third day after menstruation is clean, once a day, until menstruation stops, three months as a course of treatment, a total of four courses of treatment, if pregnant, stop treatment group B Chinese medicine take the same method as group A, three months as a course of treatment, Observe a total of four courses of treatment, if pregnant, stop treatment. The age, course of disease, pregnancy preparation time and reproductive endocrine index before treatment in the two groups were studied and analyzed. There was no significant difference between the two groups (P 0.05), and the difference was comparable. Ovulation was detected once a month. B ultrasound was recorded before and after treatment to monitor follicle and ovulation, pregnancy, endocrine hormone test data and statistical analysis. Result 1. The ovulation rate in group A was 200 cycles, the recovery cycle was 111 cycles, the ovulation rate was 55.43B group (284 cycles), and the ovulation cycle was 93 cycles (93 cycles). The ovulation rate of group A was significantly higher than that of group B after treatment. The ovulation rate of group A was higher than that of group B (P < 0.05). The pregnancy rate in group A was 21 cases after treatment, 10 cases without pregnancy, 17 cases with pregnancy after treatment in group B, 14 cases without pregnancy. The pregnancy rate of group A was 54.84.There was no significant difference between group A and group B after treatment, but the treatment cycle of group A was significantly smaller than that of group B (P 0.004 P 0.053). Statistical analysis of T in two groups before and after treatment. The difference between group A and group B was statistically significant before and after treatment. The difference was statistically significant between group A and group B, and the difference was statistically significant between group A and group B before and after treatment. Statistical analysis was made between the two groups of T indexes after treatment, the difference was statistically significant (P0. 007 / P0. 05). The difference between group A and group B was statistically significant (P0. 004) and P0. 05% (P < 0. 05). The results showed that both group A and B could decrease the level of T index, but the improvement of blood level in group A was better than that in group B. the LH/FSH of group A before and after treatment was compared with that of group B before and after treatment. The difference was statistically significant (P < 0.05). The ratio of LH/FSH in two groups after treatment was statistically analyzed. The difference was statistically significant (P < 0.05). The difference of LH/FSH ratio between group A and group B was statistically significant (P = 0.000). The data showed that both group A and B could significantly reduce the ratio of LH/FSH, and the improvement of the ratio of LH/FSH in group A was better than that in group B. Conclusion both groups can improve ovulation, and group A is superior to group B. At the same time, the two groups could increase the pregnancy rate. The pregnancy rate of group A and group B were similar after treatment, but group A could shorten the treatment cycle significantly.) both groups could significantly reduce the level of T index in blood of patients. The improvement of T index in group A was better than that in group B (P < 0.05). The level of LH/FSH in group A was significantly lower than that in group B, and the level of LH/FSH in group A was better than that in group B.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R246.3

【參考文獻】

相關(guān)期刊論文 前10條

1 孫永娟;;左歸丸加減治療多囊卵巢綜合征58例臨床研究[J];四川中醫(yī);2016年12期

2 金春蘭;龐然;徐立鵬;吳中朝;趙吉平;;針灸治療多囊卵巢綜合征臨床選穴組方規(guī)律[J];中國針灸;2015年06期

3 姚奏英;萬謙;陸華;劉霞;;左歸丸、右歸丸復(fù)方及相關(guān)成分對小鼠胚胎干細胞1B10向生殖細胞方向分化的影響[J];中國中藥雜志;2015年03期

4 謝樂;齊巧霞;;中藥外敷結(jié)合達英-35治療多囊卵巢綜合征并發(fā)痤瘡的療效觀察[J];廣西中醫(yī)藥;2014年05期

5 邢佳;傅萍;;多囊卵巢綜合征發(fā)病機制的研究進展[J];中國優(yōu)生與遺傳雜志;2014年01期

6 廖彩韻;梁曉燕;;多囊卵巢綜合征的病理生理[J];廣東醫(yī)學(xué);2013年01期

7 周軍英;朱立華;許玉剛;趙彥梅;歐建平;;經(jīng)陰道小卵泡穿刺治療多囊卵巢綜合征不孕患者80例觀察[J];中國優(yōu)生與遺傳雜志;2011年08期

8 李娟;田蔥;;女性不孕癥223例病因分析[J];現(xiàn)代中西醫(yī)結(jié)合雜志;2011年08期

9 徐江紅;佟杰;楊洪波;;耳針與中藥并用對多囊卵巢綜合征胰島素抵抗的影響[J];世界中醫(yī)藥;2011年01期

10 韋艷萍;李遠s，

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