本文選題：原發(fā)性高血壓 + 焦慮��； 參考：《安徽醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的:探討原發(fā)性高血壓與焦慮情緒的關(guān)系以及原發(fā)性高血壓伴發(fā)焦慮情緒的危險因素。方法:采用隨機抽樣的方法,收集2016年3月至2016年8月于我院心血管內(nèi)科門診就診的原發(fā)性高血壓患者84例,男53例,女31例。收集2016年3月至2016年8月于我院腫瘤科、呼吸科住院的年齡、性別、文化程度等均與研究組相匹配的其他慢性病患者,包括腫瘤患者和慢性阻塞性肺疾病患者為疾病對照組,共47例,男26例,女21例。選取年齡、性別、文化程度等均與研究組相匹配的健康志愿者為正常健康對照組,共57例,男36例,女21例。對84例原發(fā)性高血壓患者、47例其他慢性病患者以及57例健康對照分別評定漢密爾頓焦慮量表(Hamilton Anxiety Scale,HAMA)、廣泛性焦慮量表(Generalized Anxiety Disorder7-item,GAD-7)、漢密爾頓抑郁量表(Hamilton Depression Scale,HAMD)、艾森克人格問卷(Eysenck Personality Questionnaire,EPQ)。將高血壓組按高血壓分級標準分為1級、2級、3級,分析比較不同等級高血壓三組間的一般情況和各量表間的差異。并進一步比較,原發(fā)性高血壓伴與不伴焦慮情緒的一般情況和各量表之間的差異。使用多因素Logistic回歸分析尋找原發(fā)性高血壓伴發(fā)焦慮情緒的危險因素。結(jié)果:原發(fā)性高血壓組伴發(fā)焦慮情緒患者共29例,男14例,女15例,其焦慮發(fā)生率為34.52%;正常對照組焦慮患者共9人,男3例,女6例,其焦慮發(fā)生率為15.79%;其他慢性疾病組焦慮患者共12人,男11例,女1例,其焦慮發(fā)生率為25.53%。原發(fā)性高血壓組焦慮發(fā)生率顯著高于正常對照組和其他慢性疾病組(P均0.05);原發(fā)性高血壓組艾森克人格問卷-內(nèi)外向(EPQ-E)因子評分顯著低于慢性病組(P0.05),但與健康對照組差異無顯著性(P0.05);隨著原發(fā)性高血壓等級的增加,患者的焦慮和艾森克人格問卷-神經(jīng)質(zhì)(EPQ-N)因子評分逐漸增加,且1級和3級高血壓之間焦慮和神經(jīng)質(zhì)評分具有顯著差異(P0.05)。單因素分析顯示女性、病程長、血壓控制不佳、合并抑郁、高血壓分級高、高血壓危險分層高是原發(fā)性高血壓伴發(fā)焦慮的相對危險因素。多因素Logistic回歸分析示高神經(jīng)質(zhì)評分是原發(fā)性高血壓伴發(fā)焦慮的獨立危險因素。結(jié)論:焦慮發(fā)生與原發(fā)性高血壓密切相關(guān),其中神經(jīng)質(zhì)因子對焦慮發(fā)生起著重要作用。
[Abstract]:Objective: to investigate the relationship between essential hypertension and anxiety and the risk factors of anxiety in patients with essential hypertension. Methods: from March 2016 to August 2016, 84 patients with essential hypertension, 53 males and 31 females, were randomly selected. From March 2016 to August 2016, the patients with chronic diseases, including tumor patients and patients with chronic obstructive pulmonary disease (COPD), who were hospitalized in the Department of Oncology in our hospital from March 2016 to August 2016, were matched with the study group in terms of age, sex, education level, etc. There were 47 cases, 26 males and 21 females. A total of 57 healthy volunteers, 36 males and 21 females, were selected as normal control group. In 84 patients with essential hypertension, 47 patients with other chronic diseases and 57 healthy controls were assessed with Hamilton Anxiety scale, generalized Anxiety anxiety scale with generalized Anxiety disorder GAD-7, Hamilton Depression scale with Hamd, Eysenck Personality questionnaire with EPQQ. The hypertension group was divided into 1 grade, 2 grade and 3 grade according to the grade of hypertension, and the general situation and the difference of each scale among the three groups of different grades of hypertension were analyzed and compared. Furthermore, the general situation of essential hypertension with and without anxiety and the differences among the scales were compared. Multivariate Logistic regression analysis was used to find out the risk factors of anxiety in patients with essential hypertension. Results: there were 29 patients (14 males and 15 females) with anxiety in the group of essential hypertension, the incidence rate of anxiety was 34.522.In the control group, there were 9 patients with anxiety, 3 males and 6 females. The incidence of anxiety was 15.79 and the incidence of anxiety was 25.53 in 12 patients with other chronic diseases including 11 males and 1 female. The incidence of anxiety in the essential hypertension group was significantly higher than that in the normal control group and other chronic disease groups (P 0.05), and the Eysenck personality questionnaire (EPQ-EQ) score in the essential hypertension group was significantly lower than that in the chronic disease group (P 0.05), but it was significantly lower than that in the healthy control group. There was no significant difference between the two groups (P 0.05), and with the increase of the grade of essential hypertension, The scores of anxiety and Eysenck Personality questionnaire (Eysenck Personality Questions-EPQ-N) increased gradually, and there was significant difference in anxiety and neuroticism between grade 1 and grade 3 hypertension (P 0.05). Univariate analysis showed that long course of disease, poor blood pressure control, depression, high grade of hypertension and high risk stratification of hypertension were the relative risk factors of anxiety in patients with essential hypertension. Multivariate Logistic regression analysis showed that high neuroticism score was an independent risk factor for essential hypertension with anxiety. Conclusion: anxiety is closely related to essential hypertension, and neurotic factors play an important role in the occurrence of anxiety.
【學(xué)位授予單位】：安徽醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R544.11;R749.72

【參考文獻】

相關(guān)期刊論文 前10條

1 韓振;隋瑜;孫雪林;;焦慮抑郁狀態(tài)對老年高血壓患者動態(tài)血壓和血壓變異性的影響研究[J];臨床和實驗醫(yī)學(xué)雜志;2016年16期

2 張春燕;黃漢烽;張優(yōu)創(chuàng);張優(yōu)惕;張小河;;氟西汀聯(lián)合羅布麻治療伴焦慮抑郁障礙高血壓的療效觀察[J];中國實用神經(jīng)疾病雜志;2016年08期

3 丁森華;;烏靈膠囊治療原發(fā)性高血壓伴焦慮癥療效觀察[J];中國現(xiàn)代藥物應(yīng)用;2016年03期

4 朱銀潮;王永;李輝;紀威;;常見慢性病對患者生活質(zhì)量的影響[J];浙江預(yù)防醫(yī)學(xué);2016年01期

5 吳愛勤;;心身醫(yī)學(xué)分類診斷評估策略[J];實用醫(yī)院臨床雜志;2015年06期

6 駱利;郭琳;高鴻雁;談波;劉春萍;肖利軍;;基層官兵高血壓患者焦慮抑郁狀態(tài)評估[J];中國醫(yī)刊;2015年09期

7 席小紅;李新;李國芬;;血清同型半胱氨酸水平對高血壓患者焦慮情緒的影響[J];中國現(xiàn)代醫(yī)學(xué)雜志;2015年22期

8 付芙蓉;陳雨;;抗焦慮藥物輔助治療原發(fā)性高血壓臨床觀察[J];中國實用內(nèi)科雜志;2014年S2期

9 王登芹;;焦慮抑郁狀態(tài)對老年高血壓患者動態(tài)血壓影響的研究[J];中華老年心腦血管病雜志;2014年07期

10 鐘云輝;趙娟;胡明雙;唐宏;;惡性腫瘤住院患者伴發(fā)抑郁情緒相關(guān)因素調(diào)查[J];贛南醫(yī)學(xué)院學(xué)報;2014年02期

相關(guān)碩士學(xué)位論文 前2條

1 李楠;基于腦病科門診的抑郁障礙共病失眠臨床分析與病機探討[D];山東中醫(yī)藥大學(xué);2016年

2 李晨鈺;高血壓患者伴發(fā)焦慮抑郁的情況及影響因素[D];北京中醫(yī)藥大學(xué);2013年

，

本文編號：1891728