本文選題：早期肛周皮下膿腫 + 火毒蘊(yùn)結(jié)型��； 參考：《福建中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:觀察新癀片口服加外敷治療火毒蘊(yùn)結(jié)型早期肛周皮下膿腫的臨床療效。方法:將符合納入標(biāo)準(zhǔn)的60名受試者按隨機(jī)數(shù)字表隨機(jī)分為治療組和對(duì)照組。治療組予新癀片口服加外敷,對(duì)照組則予口服黃連解毒湯。兩組均以6天為治療時(shí)限,觀察患者臨床癥狀、體征及輔助檢查等指標(biāo)的變化情況,觀察新癀片口服加外敷治療火毒蘊(yùn)結(jié)型早期肛周皮下膿腫的臨床療效。結(jié)果:完成研究的病例共60例,治療組(N=30)和對(duì)照組(N=30)。治療前對(duì)兩組病例的性別、年齡、肛周疼痛、指診肛周病變腫塊觸痛、皮溫、皮色及超聲下肛周腫塊大小、CPR等進(jìn)行均衡性比較,差異均無統(tǒng)計(jì)學(xué)意義,組間基線一致,具有可比性。研究結(jié)果分析如下:(1)兩組總體療效對(duì)比情況:治療組30例患者中,治愈9例,顯效12例,有效率80%;對(duì)照組30例患者中,治愈5例,顯效6例,有效率66.67%。對(duì)比兩組總體療效有顯著性差異(P0.05)。(2)兩組患者臨床癥狀分布情況:兩組患者肛周疼痛分布在治療后及停藥1月后對(duì)比均有顯著性差異(P0.05),新癀片組療效更顯著。(3)兩組患者臨床體征分布情況:兩組患者肛周病變腫塊指診疼痛在治療后及停藥1月后對(duì)比均有顯著性差異(P0.05),新癀片組療效更顯著;兩組患者腫塊皮溫、皮色在治療后對(duì)比無顯著性差異(P0.05),但停藥一月后新癀片組療效更顯著(P0.05)。(4)兩組輔助檢查分布情況:兩組患者超聲下肛周腫塊大小改善的情況在治療后及停藥1月后比較有顯著差異(P.0.05),新癀片組療效更顯著;兩組在治療后CRP分布情況比較無顯著差異(P.0.05),但停藥一月后新癀片組療效更顯著(P.0.05)。(5)復(fù)發(fā)及不良反應(yīng)情況:兩組停藥1月后的復(fù)發(fā)情況比較有顯著性差異(P0.05),實(shí)驗(yàn)過程中,兩組在用藥過程中均未出現(xiàn)明顯不良反應(yīng)。結(jié)論:新癀片口服加外敷治療火毒蘊(yùn)結(jié)型早期肛周皮下膿腫,能明顯減輕患者肛周疼痛、皮溫及皮色,改善腫塊大小及降低CRP等情況,尤其在減輕患者肛周疼痛、改善腫塊大小上有明顯優(yōu)勢(shì)。實(shí)驗(yàn)階段尚未發(fā)現(xiàn)不良反應(yīng),短期復(fù)發(fā)率較低,是一種有效且相對(duì)較安全的治療方法。
[Abstract]:Objective: To observe the clinical effect of the oral and external application of new tablets in the treatment of early perianal abscess of anorectal abscess. Methods: 60 subjects were randomly divided into the treatment group and the control group according to the random number table. The treatment group was given the new tablets orally plus external application, and the control group was given oral Huanglian Jiedu soup. The two groups were treated with 6 days as the treatment. To observe the changes of the clinical symptoms, signs and auxiliary examination of the patients, observe the clinical effect of the oral and external application of the new tablet in the treatment of the early perianal abscess of the poison implication type. Results: 60 cases were completed, the treatment group (N=30) and the control group (N=30). The sex, age, perianal pain, and finger diagnosis of the two groups of cases before treatment. The pain of perianal lesions, skin temperature, skin color and ultrasonic perianal mass size, CPR and so on were compared, the differences were not statistically significant, the baseline of the group was the same. The results were as follows: (1) the total effect of the two groups was compared: in the 30 patients of the treatment group, 9 cases were cured, 12 cases were markedly effective and 30 patients in the control group. In the 5 cases, 5 cases were cured, 6 cases were markedly effective, and the total effective difference between the two groups was significantly different (P0.05). (2) the distribution of clinical symptoms in the two groups: the two groups were significantly different in the distribution of perianal pain after the treatment and after the withdrawal of the drug after January (P0.05). (3) the distribution of clinical signs in the two groups: two groups. There were significant differences in the pain between the patients after the perianal lesion and after the drug withdrawal in January (P0.05), and the effect of the new group was more significant. There was no significant difference between the two groups of mass skin temperature and skin color (P0.05) after the treatment (P0.05). (4) the distribution of two groups of auxiliary examinations: two groups of patients. The improvement of the size of the perianal mass was significantly different after the treatment and after the withdrawal in January (P.0.05). The effect of the new group was more significant (P.0.05). There was no significant difference in the CRP distribution in the two groups after the treatment (P.0.05). (5) the recurrence and adverse reaction: the two group stopped after January. There was a significant difference in recurrence (P0.05). During the experiment, the two groups had no obvious adverse reactions during the course of the drug use. Conclusion: the oral and external application of new tablets in the treatment of early perianal abscess in the early perianal abscess can obviously reduce the pain of the anus, skin temperature and skin color, improve the size of the mass and reduce the condition of CRP. It is an effective and relatively safe treatment to light patients with perianal pain and to improve the size of the mass.

【學(xué)位授予單位】：福建中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R266

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