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胃癌耳穴特異性變化的臨床研究

發(fā)布時間:2018-05-01 10:04

  本文選題:胃癌 + 耳穴 ; 參考:《大連醫(yī)科大學(xué)》2017年碩士論文


【摘要】:目的:通過耳穴望診、觸診及電測三種方法對臨床胃癌患者雙耳耳廓相關(guān)耳穴特異性變化進行觀察研究,進行耳穴診斷胃癌相關(guān)性、相符率的比較,為進一步研究通過耳穴輔助診斷胃癌提供參考。為臨床早期發(fā)現(xiàn)胃癌提供簡便、安全、經(jīng)濟、可靠的初步篩查診斷方法。方法:根據(jù)既往研究經(jīng)驗與耳穴診斷理論選取雙耳耳穴口、食管、賁門、胃、十二指腸、小腸、大腸、肝、脾、皮質(zhì)下、腎上腺、腫瘤特異區(qū)(M1、M2、M3),共14個穴位。分別采用耳穴望診法、觸診法以及電測法,對39例胃癌術(shù)前患者,35例慢性萎縮性胃炎患者以及36例健康者耳廓進行相關(guān)穴位特異性變化的臨床觀察與檢測。記錄相關(guān)耳穴顏色和形態(tài)的變化,并用相機采集照片,然后用Adobe photoshopCS6對照片進行處理后,進行色差分析。分別用XDM-III型耳穴探測儀和CLRH-A型耳穴探測器共同檢測胃癌患者、慢性萎縮性胃炎患者及健康人雙耳耳穴的低電阻陽性反應(yīng)點,并加以記錄。然后用SPSS22.0進行統(tǒng)計分析,分別比較胃癌患者、慢性萎縮性胃炎患者以及健康人之間耳廓的相關(guān)耳穴差異性。結(jié)果:1.胃癌組與健康人組比較:在顏色、形態(tài)以及電測上兩組均存在著明顯差異性。(1)顏色上,尤其在耳穴胃區(qū)和腫瘤特異區(qū)II(M2)改變最為明顯,胃癌組耳穴胃區(qū)與健康組相比顏色晦暗無光,部分患者出現(xiàn)褐色斑點,腫瘤特異區(qū)II出現(xiàn)暗灰色或棕褐色色斑,胃區(qū)與腫瘤特異區(qū)改變與健康組比較均存在統(tǒng)計學(xué)差異(P0.01,P0.01),經(jīng)色差分析比較,存在的統(tǒng)計學(xué)差異(P0.01,P0.01)。(2)形態(tài)上,胃癌組大多數(shù)患者胃區(qū)出現(xiàn)結(jié)節(jié)改變,與健康組相比差異具有顯著統(tǒng)計學(xué)意義(P0.01)。(3)電測上,胃癌組賁門、胃、十二指腸、脾、皮質(zhì)下、腫瘤特異區(qū)(M1、M3)出現(xiàn)大量陽性反應(yīng),與健康組相比差異具有顯著統(tǒng)計學(xué)意義(P0.01)。2.胃癌組與慢性萎縮性胃炎組比較:(1)顏色上,胃癌組與慢性萎縮性胃炎組相比出現(xiàn)較多例數(shù)胃區(qū)呈棕褐色或暗灰色改變以及腫瘤特異區(qū)II(M2)呈暗灰色或棕褐色色斑改變,差異均有統(tǒng)計學(xué)意義(P0.05,P0.05),通過色差分析比較,均具有統(tǒng)計學(xué)差異(P0.05,P0.05)。(2)形態(tài)上,胃癌組胃區(qū)出現(xiàn)結(jié)節(jié)改變較慢性萎縮性胃炎患者組明顯增多,有統(tǒng)計學(xué)差異(P0.05)。(3)電測上,胃癌組耳穴胃、皮質(zhì)下較慢性萎縮性胃炎組出現(xiàn)低電阻陽性反應(yīng)多,差異具有統(tǒng)計學(xué)意義(P0.05)。腫瘤特異區(qū)(M1、M3)出現(xiàn)大量陽性反應(yīng),與慢性萎縮性胃炎組相比差異具有顯著統(tǒng)計學(xué)意義(P0.01)。3.慢性萎縮性胃炎組與健康組比較:(1)顏色上,在胃區(qū)和腫瘤特異區(qū)II(M2)顏色改變上無統(tǒng)計學(xué)差異。但通過色差分析,健康組與萎縮性胃炎組在胃區(qū)和腫瘤特異區(qū)II(M2)存在色差差異(P0.05,P0.05)。(2)形態(tài)上,部分慢性萎縮性胃炎患者出現(xiàn)胃區(qū)結(jié)節(jié)改變,與健康組組相比差異具有統(tǒng)計學(xué)意義(P0.01)。(3)電測上,胃癌組與健康組比較在賁門、胃、十二指腸、脾、皮質(zhì)下均具有顯著統(tǒng)計學(xué)差異(P0.01)。腫瘤特異區(qū)(M1、M3)則無統(tǒng)計學(xué)意義。結(jié)論:胃癌患者與健康人和慢性萎縮性胃炎患者比較,在耳廓相關(guān)耳穴的顏色、形態(tài)以及電測上均存在著明顯差異。充分說明耳穴診斷法對胃癌具有一定的臨床輔助診斷價值,在胃癌的普查中值得進一步的探究與推廣。
[Abstract]:Objective: To observe and study the auricular specific changes of the auricular auricle in the clinical gastric cancer patients by three methods of auricular acupoint inspection, palpation and electrical measurement, and the correlation of the diagnosis of gastric cancer by ear acupoint diagnosis, and the comparison of the coincidence rate for the further study of the diagnosis of gastric cancer by ear acupoint assistance. It provides a simple, safe and economical method for the early detection of gastric cancer. A reliable preliminary screening diagnostic method. Methods: according to the previous research experience and ear point diagnosis theory, we selected the auricular acupoint mouth, the esophagus, the cardia, the stomach, the duodenum, the small intestine, the large intestine, the liver, the spleen, the cortex, the adrenal gland, the tumor specific area (M1, M2, M3), with 14 points, respectively, with the auricular examination, palpation and electrical measurement, respectively, for the preoperative suffering of 39 cases of gastric cancer. In 35 cases of chronic atrophic gastritis and 36 healthy subjects, the specific changes in the auricle of the auricle were observed and detected. The changes in the color and shape of the auricular points were recorded, and the photographs were collected with a camera, and then the color difference was analyzed with Adobe photoshopCS6. The XDM-III type auricular probe and CLR were used respectively. H-A type auricular detector was used to detect and record the low resistance positive reaction point of gastric cancer patients, chronic atrophic gastritis and healthy people, and then recorded by SPSS22.0, and then compared the auricular points of gastric cancer patients, chronic atrophic gastritis and healthy people. Results: 1. gastric cancer group. Compared with the healthy group, there were obvious differences between the two groups in color, shape and electrical test. (1) the color, especially in the auricular area and the tumor specific area II (M2) was most obvious, the gastric area of the gastric cancer group was dark and dark compared with the health group, some patients appeared brown spots, and the tumor specific area II appeared dark grey or brown. There were significant differences in color spots, gastric area and tumor specific area changes (P0.01, P0.01), and the statistical difference (P0.01, P0.01) compared with the color difference analysis (P0.01, P0.01). (2) in the form of gastric cancer, most of the patients had nodular changes in gastric area, and there were significant statistical significance (P0.01). (3) gastric carcinoma group cardia cardia. A large number of positive reactions were found in the portal, stomach, duodenum, spleen, subcortex and tumor specific area (M1, M3). Compared with the healthy group, the difference was significant (P0.01) compared with the chronic atrophic gastritis group (P0.01): (1) the color, gastric cancer group and chronic atrophic gastritis group had many cases of brown or dark grey change in the gastric region. And the tumor specific area II (M2) showed a dark grey or brown color spot change, the difference was statistically significant (P0.05, P0.05), by color difference analysis, all had statistical differences (P0.05, P0.05). (2) the morphological changes of gastric cancer group were significantly increased in gastric cancer group than chronic atrophic gastritis patients (P0.05). (3) electric test, stomach The positive reaction of low resistance in the cancer group was more than that in the chronic atrophic gastritis group. The difference was statistically significant (P0.05). The tumor specific area (M1, M3) had a large number of positive reactions. Compared with the chronic atrophic gastritis group, the difference had significant statistical significance (P0.01).3. chronic atrophic gastritis group was compared with the healthy group: (1) color, There was no statistical difference in the color change of II (M2) in the stomach and tumor specific areas. But by color difference analysis, there was a difference in color difference between the healthy group and the atrophic gastritis group in the gastric region and the tumor specific area II (M2) (P0.05, P0.05). (2) part of the chronic atrophic gastritis patients showed the change of the gastric nodule, and the difference was statistically significant compared with the healthy group. Significance (P0.01). (3) electrical measurement, the gastric cancer group and the health group compared to the cardia, stomach, duodenum, spleen, cortex all have significant statistical difference (P0.01). The tumor specific area (M1, M3) has no statistical significance. Conclusion: gastric cancer patients and healthy people and chronic atrophic gastritis patients, in the auricle related auricular color, morphology and electrical measurement are all There are obvious differences. It is fully explained that the auricular point diagnosis has certain clinical auxiliary diagnostic value for gastric cancer, and it is worth further exploring and popularizing in the general survey of gastric cancer.

【學(xué)位授予單位】:大連醫(yī)科大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2017
【分類號】:R735.2


本文編號:1828848

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