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腹腔鏡與開(kāi)腹結(jié)腸癌CME手術(shù)臨床療效比較研究

發(fā)布時(shí)間:2018-04-29 20:43

  本文選題:腹腔鏡 + 結(jié)腸癌; 參考:《青海大學(xué)》2017年碩士論文


【摘要】:目的:對(duì)比腹腔鏡CME手術(shù)與開(kāi)腹CME手術(shù)治療結(jié)腸癌的療效。方法:分析青大附院腫瘤外科在2015年3月到2016年5月之間完成的腹腔鏡CME及開(kāi)腹CME手術(shù)共47例,通過(guò)分析兩組的手術(shù)時(shí)間、術(shù)中出血量、術(shù)后離床時(shí)間、術(shù)后首次排氣時(shí)間、術(shù)后進(jìn)流食時(shí)間、術(shù)后在院天數(shù)、總費(fèi)用、清掃而獲得的淋巴結(jié)數(shù)目、病理標(biāo)本腫瘤大小、遠(yuǎn),近切緣距離,術(shù)后并發(fā)癥發(fā)生率臨床指標(biāo)而得出結(jié)論。結(jié)果:通過(guò)對(duì)比,兩組患者的一般資料如年齡,性別,體重指數(shù)(BMI),腫瘤所處位置及術(shù)前腫瘤的臨床分期未見(jiàn)明顯差異。腹腔鏡組與開(kāi)腹組在手術(shù)失血量(79.3±8.3ml,123.9±10.1ml,P0.05),術(shù)后下床時(shí)間(21.7±6.6h,25.8±6.5h,P0.05),術(shù)后排氣時(shí)間(70.7±6.8h,80.2±6.1h,P0.05),術(shù)后住院天數(shù)(10.9±3.9d,14.5±3.3d,P0.05)方面的差異有統(tǒng)計(jì)學(xué)意義,而兩者在手術(shù)時(shí)間(176.9±16.8min,167.1±16.6min,P0.05),清掃淋巴結(jié)數(shù)目(18.5±4.5,19.9±4.1,P0.05)、近切緣距離(14.7±3.5,13.5±5.2cm,p0.05)、遠(yuǎn)切緣距離(17.5±8.0,20.7±8.6cm,p0.05)、腫瘤大小(5.8±1.2,5.1±1.5cm,p0.05)、術(shù)后并發(fā)癥發(fā)生率(7.4%,20%,p0.05)、Clavien-Dindo分級(jí)為Ⅰ,Ⅱ級(jí)患者所占比例(7.4%,20%,p0.05)總費(fèi)用(6.3±1.1萬(wàn)元,6.2±1.6萬(wàn)元,P0.05)方面的差異無(wú)統(tǒng)計(jì)學(xué)意義。結(jié)論:腹腔鏡CME手術(shù)具有出血量少,康復(fù)快的優(yōu)點(diǎn),同時(shí)在安全性及腫瘤根治的方面能達(dá)到和開(kāi)腹CME手術(shù)相當(dāng)?shù)男Ч?br/>[Abstract]:Objective: to compare the efficacy of laparoscopic CME operation and open CME operation in the treatment of colon cancer. Methods: a total of 47 cases of laparoscopic CME and open CME were performed in tumor surgery of Qingda affiliated Hospital from March 2015 to May 2016. The time of operation, intraoperative bleeding, postoperative time out of bed and the time of first postoperative exhaust were analyzed in the two groups. The time of feeding, the days in hospital, the total cost, the number of lymph nodes obtained by dissection, the size, distance and distance of tumor, and the incidence of postoperative complications were analyzed. Results: there was no significant difference in general data such as age, sex, body mass index (BMI), tumor location and preoperative clinical stage between the two groups. There were significant differences in blood loss (79.3 鹵8.3 ml), postoperative time (21.7 鹵6.6 h), postoperative time (25.8 鹵6.5 h, P 0.05), postoperative exhaust time (70.7 鹵6.8 h, 80.2 鹵6.1 h, P 0.05), postoperative hospitalization days (10.9 鹵3.9dU, 14.5 鹵3.3dg, P 0.05) between the laparoscopic group and the laparotomy group, and there was significant difference between the laparoscopic group and the laparotomy group in terms of postoperative blood loss (79.3 鹵8.3ml), postoperative time of getting out of bed (21.7 鹵6.6hs, 25.8 鹵6.5hP0.05), postoperative days of hospitalization (10.9 鹵3.9dU, 14.5 鹵3.3dg). The operative time was 176.9 鹵16.8min, 167.1 鹵16.6 min, P0.05, the number of lymph nodes dissected, 14.7 鹵3.5cm. 13.5 鹵5.2cm, 17.5 鹵8.020.7 鹵8.6cmp0.05, and the size of tumor 5.8 鹵1.2cm. p0.05. the incidence of postoperative complications was 7.420p0.05p0.05. the incidence of postoperative complications was 7.420p0.05p0.05a, and the classification of Clavien-Dindo was 鈪,

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