本文選題：膽紅素　切入點(diǎn)：PCI　出處：《浙江大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:通過回顧性研究分析接受擇期經(jīng)皮冠脈介入治療(percutaneous coronary intervention,PCI)患者術(shù)前血清膽紅素水平與圍手術(shù)期心肌損傷(periprocedural myocardial injury,PMI)的相關(guān)性。方法:本研究回顧性分析行擇期PCI術(shù)的2356例連續(xù)病例,收集PCI術(shù)后8、16、24小時(shí)血清肌鈣蛋白Ⅰ和CKMB峰值,以及PCI術(shù)前血清膽紅素?cái)?shù)據(jù),終點(diǎn)事件為PMI(定義為PCI術(shù)后24小時(shí)內(nèi)肌鈣蛋白Ⅰ或CKMB峰值≥5倍參考值上限),通過logistic回歸分析并探討術(shù)前血清膽紅素水平和圍手術(shù)期心肌損傷的相關(guān)性。結(jié)果:兩組間比較,PMI組患者術(shù)前膽紅素水平低于非PMI組(13.2 vs14.1μmol/L,p=0.019)。經(jīng)過多因素logistic回歸分析提示術(shù)前高水平膽紅素組(膽紅素15.3μmol/L)患者與低水平膽紅素組(膽紅素10.6μmol/L)患者相比,術(shù)后PMI的發(fā)生風(fēng)險(xiǎn)較低(OR:0.699,95%CI:0.531-0.921,p=0.011)。結(jié)論:擇期PCI術(shù)前血清膽紅素水平與PMI的發(fā)生風(fēng)險(xiǎn)相關(guān),較高的血清膽紅素水平可以降低術(shù)后PMI的發(fā)生率。
[Abstract]:Objective: to analyze the correlation between preoperative bilirubin level and perioperative perioperative myocardial injury myocardial injury-PMIs in patients undergoing percutaneous coronary intervention (PCI) with percutaneous coronary intervention (PCI). Methods: PCI was performed retrospectively in this study. Of 2356 consecutive cases of surgery, The peak values of serum troponin I and CKMB and serum bilirubin before PCI were collected at 816 hours after PCI. The endpoint event was PMI (defined as troponin I or CKMB peak value 鈮，

本文編號(hào)：1602811