本文選題：負(fù)重區(qū)　切入點(diǎn)：關(guān)節(jié)軟骨　出處：《新疆醫(yī)科大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的分析正常成年新西蘭大白兔膝關(guān)節(jié)脛骨關(guān)節(jié)軟骨的表觀彌散系數(shù)(ADC)值和部分各向異性指數(shù)(FA)值,確定脛骨關(guān)節(jié)軟骨負(fù)重區(qū)范圍、為軟骨退變疾病研究過程中選取最典型的取材部位提供參考和提高實(shí)驗(yàn)結(jié)果的準(zhǔn)確性。方法選用正常成年新西蘭大白兔28只,進(jìn)行矢狀位三維擾相脂肪抑制梯度回波(3D-WATS)序列和矢狀位彌散張量成像(DTI)掃描,掃描后圖像在工作站測量關(guān)節(jié)軟骨的ADC值和FA值。將脛骨表面軟骨由前到后分為A、B、C、D、E組,分析各組間ADC值和FA值有無差異。結(jié)果脛骨平臺(tái)內(nèi)外側(cè)軟骨間ADC值和FA值的比較經(jīng)Mann-Whitney U秩和檢驗(yàn),差異無統(tǒng)計(jì)學(xué)意義(ZADC=-0.267,P=0.7900.05;ZFA=-0.751,P=0.4530.05),每側(cè)中A、B、C、D、E組間ADC值和FA值的差異有統(tǒng)計(jì)學(xué)意義(P㩳0.05),同側(cè)不同組間兩兩比較中其中外側(cè)中C組與E組間ADC值和FA值的差異無統(tǒng)計(jì)學(xué)意義(P㧐0.05),內(nèi)側(cè)中C組與D組間ADC值的差異也無統(tǒng)計(jì)學(xué)意義(P=0.231㧐0.05),FA值無統(tǒng)計(jì)學(xué)意義,其余各組間ADC值和FA值的差異有統(tǒng)計(jì)學(xué)意義。結(jié)論正常成年新西蘭大白兔脛骨軟骨內(nèi)外側(cè)無差別,由前至后不同區(qū)間有差別,負(fù)重區(qū)位于由前至后的4/5區(qū),對(duì)于關(guān)節(jié)軟骨退變的研究區(qū)域來講,該區(qū)為理想的觀察和檢測區(qū)域。
[Abstract]:Objective to analyze the apparent diffusion coefficient (ADCC) and partial anisotropy index (FAA) of tibial articular cartilage of normal adult New Zealand white rabbits, and to determine the area of tibial articular cartilage bearing weight. Methods 28 normal adult New Zealand white rabbits were used to select the most typical materials and improve the accuracy of the experimental results. The sagittal 3D disturbed phase fat suppression gradient echo (3D-WATS) sequence and sagittal diffusion Zhang Liang imaging (DTI) scan were performed. The ADC and FA values of articular cartilage were measured on workstation after scanning. The tibial surface cartilage was divided into two groups from anterior to posterior. Results there was no significant difference in ADC value and FA value between the internal and external sides of tibial plateau by Mann-Whitney U rank summation test. There was no significant difference between them by Mann-Whitney U rank sum test. There was no significant difference in ADC and FA value between the two groups. There was no significant difference in ADC value and FA value between the two groups (P > 0.05), but there was no significant difference in ADC value and FA value between the two groups (P > 0.05). The results showed that there was no significant difference in ADC and FA value between the two groups (P > 0.05), but there was no significant difference in ADC value and FA value between the two groups (P > 0.05). There was no significant difference in ADC and FA between the lateral middle C group and E group. There was no significant difference in ADC value between group C and group D in the medial middle of group C and group D, and there was no significant difference in ADC value between group C and group D. There was no significant difference in FA value among the other groups. Conclusion there was no difference in the inner and outer sides of tibial cartilage in normal adult New Zealand white rabbits, but there was difference in different regions from anterior to posterior, and the weight bearing area was located in the 4/5 area from front to back. For the study area of articular cartilage degeneration, this area is an ideal observation and detection area.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R445.2;R684

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 王俊江;肖國強(qiáng);閆軍;陶開亮;秦旭棟;顧慶陟;高興;田征;;正常成年兔膝關(guān)節(jié)軟骨ADC值和FA值的定量分析[J];新疆醫(yī)科大學(xué)學(xué)報(bào);2017年03期

2 趙丹丹;李紅;秦灝;張永學(xué);李娜;劉s，

本文編號(hào)：1595933