天堂国产午夜亚洲专区-少妇人妻综合久久蜜臀-国产成人户外露出视频在线-国产91传媒一区二区三区

有無均整器模式下高危神經(jīng)母細(xì)胞瘤容積弧形調(diào)強(qiáng)放療計(jì)劃的劑量學(xué)比較

發(fā)布時(shí)間:2018-01-16 19:43

  本文關(guān)鍵詞:有無均整器模式下高危神經(jīng)母細(xì)胞瘤容積弧形調(diào)強(qiáng)放療計(jì)劃的劑量學(xué)比較 出處:《吉林大學(xué)》2017年碩士論文 論文類型:學(xué)位論文


  更多相關(guān)文章: 神經(jīng)母細(xì)胞瘤 容積弧形調(diào)強(qiáng)放療技術(shù) 劑量學(xué) 非均整模式


【摘要】:目的:比較6 MV X射線非均整模式(FFF)和均整模式(FF)下容積調(diào)強(qiáng)弧形放射治療(Rapid Arc)在高危神經(jīng)母細(xì)胞瘤術(shù)后放療中的劑量學(xué)差異,為臨床高危神經(jīng)母細(xì)胞瘤術(shù)后患者選擇最佳放療技術(shù)提供參考。材料和方法:選擇高危神經(jīng)母細(xì)胞瘤術(shù)后患者10例,行CT模擬定位,并勾畫靶區(qū)及危及器官。分別對每例患者設(shè)計(jì)FFF和FF Rapid Arc計(jì)劃,比較兩種計(jì)劃靶區(qū)的最大劑量(Dmax)、平均劑量(Dmean)、靶區(qū)適形指數(shù)(CI)、均勻性指數(shù)(HI)、危及器官的受量、機(jī)器跳數(shù)和治療時(shí)間。結(jié)果:(1)與FF Rapid Arc治療計(jì)劃相比,FFF Rapid Arc治療計(jì)劃的PTV的Dmax和Dmean均明顯增高,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。FF和FFF Rapid Arc治療計(jì)劃的CI分別為0.85±0.03和0.84±0.04(P0.05),HI分別為1.057±0.01和1.062±0.01(P0.05)。(2)FFF Rapid Arc計(jì)劃顯著降低了小腸V10和Dmean(P0.05);FFF Rapid Arc計(jì)劃顯著降低了腎臟V10明顯降低(P0.05)。(3)FFF Rapid Arc計(jì)劃的機(jī)器跳數(shù)是(474.92±69.37)MU,FF計(jì)劃的機(jī)器跳數(shù)是(450.92±61.90)MU。兩種計(jì)劃治療時(shí)間均約2 min,無統(tǒng)計(jì)學(xué)差異。結(jié)論:兩種計(jì)劃均能滿足臨床治療需求,FF計(jì)劃較FFF Rapid Arc計(jì)劃提供了更好的靶區(qū)劑量分布,FFF Rapid Arc計(jì)劃更利于保護(hù)射野邊緣危及器官,如腎臟和小腸。雖然FFF Rapid Arc計(jì)劃的機(jī)器跳數(shù)高于FF Rapid Arc治療計(jì)劃,大分割照射時(shí),FFF模式能明顯減少治療時(shí)間,縮短治療時(shí)間,減少治療中體位移動誤差,達(dá)到精準(zhǔn)治療。但由于本研究是常規(guī)劑量照射,兩者的治療時(shí)間無明顯差別。
[Abstract]:Objective: to compare the effect of Volumetric intensity modulated arc radiotherapy (VIMRT) on rapid Arc under 6 MV X ray nonuniform mode FFFFFFFFFFFFFFFFFFFFF). Dosimetric differences in postoperative radiotherapy for high-risk neuroblastoma. Materials and methods: 10 patients with high risk neuroblastoma were selected for CT simulation localization. FFF and FF Rapid Arc plans were designed for each patient, and the maximum dose of Dmaxin the two target areas was compared. The mean dose was Dmean, the conformal index of target area was CI, the index of homogeneity was high, and the organ acceptance was endangered. Number of machine jumps and duration of treatment. Results: 1) compared with FF Rapid Arc treatment plan. Both Dmax and Dmean of PTV in FFF Rapid Arc treatment plan were significantly increased. The CI of FFF Rapid Arc was 0.85 鹵0.03 and 0.84 鹵0.04, respectively. The HI values of 1.057 鹵0. 01 and 1. 062 鹵0. 01 P0. 05 Rapid Arc significantly decreased the intestinal V10 and Dmean (P < 0. 05). P0.05; The FFF Rapid Arc program significantly reduced kidney V10, significantly reduced the number of machine hops in the P0. 05 Rapid Arc program. 474.92 鹵69.37 MU. The number of machine hops in FF plan was 450.92 鹵61.90 mu. There was no statistical difference in the time of treatment between the two plans. Conclusion: the two plans can meet the needs of clinical treatment. Compared with the FFF Rapid Arc program, FF program provides better target dose distribution. FFF Rapid Arc program is more helpful to protect the organ at the edge of the field. For example, kidney and small intestine. Although the number of machine hops in the FFF Rapid Arc program is higher than that in the FF Rapid Arc treatment plan, the treatment time can be significantly reduced by using the FFF mode during large segment irradiation. The treatment time was shortened, the position movement error was reduced, and the accurate treatment was achieved. However, there was no significant difference in the treatment time between the two groups because of the conventional dose irradiation in this study.
【學(xué)位授予單位】:吉林大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2017
【分類號】:R739.4;R730.55

【參考文獻(xiàn)】

相關(guān)期刊論文 前9條

1 查元梓;吳曄明;陸冬青;袁曉軍;蔣馬偉;;兒童神經(jīng)母細(xì)胞瘤三維適形放射治療與調(diào)強(qiáng)放射治療劑量學(xué)比較[J];中國醫(yī)學(xué)物理學(xué)雜志;2016年02期

2 楊婷;胡顯良;王珊;;神經(jīng)母細(xì)胞瘤治療進(jìn)展[J];中國小兒血液與腫瘤雜志;2015年06期

3 ;兒童神經(jīng)母細(xì)胞瘤診療專家共識[J];中華小兒外科雜志;2015年01期

4 陳燕飛;王天有;;神經(jīng)母細(xì)胞瘤的治療新進(jìn)展[J];中華實(shí)用兒科臨床雜志;2014年15期

5 黃東生;張誼;;兒童神經(jīng)母細(xì)胞瘤分層化療[J];中國小兒血液與腫瘤雜志;2014年01期

6 李圓;朱孝宇;;溶瘤腺病毒治療神經(jīng)母細(xì)胞瘤的研究進(jìn)展[J];中華小兒外科雜志;2014年02期

7 王娟;甄子俊;劉鈞澄;劉卓煒;朱佳;蔡月;凌家瑜;陳燕;蔡瑞卿;孫曉非;高遠(yuǎn)紅;;Ⅳ期高危神經(jīng)母細(xì)胞瘤原發(fā)病變部位局部放療的價(jià)值[J];中華放射腫瘤學(xué)雜志;2012年01期

8 熊稀霖;黎陽;;復(fù)發(fā)性或難治性神經(jīng)母細(xì)胞瘤的治療進(jìn)展[J];中國小兒血液與腫瘤雜志;2011年01期

9 李凱;神經(jīng)母細(xì)胞瘤的治療進(jìn)展[J];中華小兒外科雜志;2002年02期



本文編號:1434567

資料下載
論文發(fā)表

本文鏈接:http://sikaile.net/shoufeilunwen/mpalunwen/1434567.html


Copyright(c)文論論文網(wǎng)All Rights Reserved | 網(wǎng)站地圖 |

版權(quán)申明:資料由用戶7ddd0***提供,本站僅收錄摘要或目錄,作者需要刪除請E-mail郵箱bigeng88@qq.com
欧美国产极品一区二区| 少妇福利视频一区二区| 国产传媒中文字幕东京热| 大香蕉久久精品一区二区字幕| 日韩精品福利在线观看| 日韩一区二区三区有码| 中文人妻精品一区二区三区四区| 东京热男人的天堂久久综合| 国产日韩欧美在线播放| 亚洲天堂久久精品成人| 午夜精品国产精品久久久| 欧美日韩一区二区综合| 欧美同性视频免费观看| 欧美日韩精品一区免费| 国产黑人一区二区三区| 亚洲精品美女三级完整版视频| 青青操精品视频在线观看| 91超精品碰国产在线观看| 国产精品日本女优在线观看| 亚洲综合精品天堂夜夜| 国产不卡的视频在线观看| 黄片免费播放一区二区| 久久精品蜜桃一区二区av| 精品香蕉国产一区二区三区| 欧美日韩精品综合一区| 国产又粗又猛又长又黄视频| 国产又色又爽又黄又免费| 免费观看一级欧美大片| 国产真人无遮挡免费视频一区| 97人妻精品一区二区三区男同| 日韩欧美第一页在线观看| 樱井知香黑人一区二区| 亚洲中文在线观看小视频| 在线观看免费无遮挡大尺度视频| 国产中文字幕久久黄色片| 亚洲中文字幕有码在线观看| 91免费一区二区三区| 老司机精品视频在线免费看| 冬爱琴音一区二区中文字幕 | 色播五月激情五月婷婷| 日本和亚洲的香蕉视频|