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眶上外側(cè)入路與單側(cè)額下入路顯微切除嗅溝腦膜瘤的臨床效果比較

發(fā)布時(shí)間:2018-01-03 20:28

  本文關(guān)鍵詞:眶上外側(cè)入路與單側(cè)額下入路顯微切除嗅溝腦膜瘤的臨床效果比較 出處:《浙江大學(xué)》2017年碩士論文 論文類型:學(xué)位論文


  更多相關(guān)文章: 嗅溝腦膜瘤 眶上外側(cè)入路 單側(cè)額下入路 顯微手術(shù)


【摘要】:目的單側(cè)額下入路是嗅溝腦膜瘤顯微切除常用的手術(shù)入路,眶上外側(cè)入路具有便捷、美觀、微創(chuàng)的優(yōu)勢,近年來也逐漸被應(yīng)用于嗅溝腦膜瘤顯微切除。本文旨在從安全性、有效性等方面對兩種手術(shù)方式進(jìn)行比較分析。方法回顧性收集2013年6月1日至2017年1月1日在浙江大學(xué)醫(yī)學(xué)院附屬第二醫(yī)院神經(jīng)外科行嗅溝腦膜瘤手術(shù)的65例患者資料,根據(jù)手術(shù)方法歸為眶上外側(cè)入路組(A組,n = 22)和單側(cè)額下入路組(B組,n = 23),隨訪至2017年3月1日,收集兩組患者的基本資料、手術(shù)時(shí)間、術(shù)中出血量、手術(shù)切除程度、住院時(shí)間、術(shù)后并發(fā)癥、隨訪結(jié)果等信息,從手術(shù)安全性、有效性等方面進(jìn)行比較。結(jié)果A組與B組患者在手術(shù)時(shí)間、手術(shù)切除程度、術(shù)后嗅功能視功能改變、出院GOS評分、隨訪終點(diǎn)GOS評分、隨訪終點(diǎn)KPS評分、復(fù)發(fā)率、死亡率方面無顯著性差異。A組患者需手術(shù)干預(yù)的并發(fā)癥率小于B組(0.0%vs4.3%,P0.05),但亦無統(tǒng)計(jì)學(xué)差異。兩組的術(shù)中出血量(179.55±89.52mlvs267.39± 147.41ml,P0.05)、住院時(shí)間(14.14 ± 3.54 天 vs 18.52 ±5.27 天,P0.05)上的差異顯著。結(jié)論眶上外側(cè)入路相比于單側(cè)額下入路在能夠安全全切嗅溝腦膜瘤的同時(shí)具有術(shù)中出血量少、住院時(shí)間短、嚴(yán)重并發(fā)癥少等優(yōu)勢,值得進(jìn)一步推廣。
[Abstract]:Objective unilateral subfrontal approach is a common surgical approach for the microresection of olfactory sulcus meningiomas. The supraorbital approach is convenient, beautiful and minimally invasive. In recent years, it has been gradually used in the microexcision of olfactory sulcus meningiomas. Methods from June 1st 2013 to January 1st 2017, olfactory sulcus meningiomas were collected retrospectively from June 1st 2013 to January 1st 2017 in the second affiliated Hospital of Zhejiang University School of Medicine. Data of 65 patients undergoing surgery. According to the operative method, group A (n = 22) and group B (group B) were divided into two groups: supra-lateral orbital approach group (n = 22) and subfrontal approach group B group (n = 23), followed up until March 1st 2017. To collect the basic information, operative time, intraoperative bleeding volume, surgical resection degree, hospitalization time, postoperative complications, follow-up results and other information from the safety of the operation. Results in group A and group B, the operative time, the degree of resection, the changes of olfactory function after operation, the GOS score of discharge, and the GOS score at the end of follow-up were compared. There was no significant difference in KPS score, recurrence rate and mortality. The complication rate in group A was lower than that in group B (P 0.05). However, there was no statistical difference between the two groups. The intraoperative bleeding volume was 179.55 鹵89.52 ml vs 267.39 鹵147.41 ml P0.05). The hospital stay was 14.14 鹵3.54 days vs 18.52 鹵5.27 days. Conclusion compared with the unilateral subfrontal approach, the supraorbital approach has the advantages of less intraoperative bleeding, shorter hospital stay and less severe complications. It is worth further popularizing.
【學(xué)位授予單位】:浙江大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R739.45

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相關(guān)期刊論文 前5條

1 閆憲磊;鄭捷敏;黃河清;陳家康;肖振勇;;眶上外側(cè)入路顯微手術(shù)切除嗅溝腦膜瘤22例臨床報(bào)道[J];中華神經(jīng)醫(yī)學(xué)雜志;2016年12期

2 張寅;李永財(cái);;單、雙側(cè)額下入路切除大型嗅溝腦膜瘤的效果比較[J];中國腫瘤外科雜志;2016年01期

3 馬翔宇;張鑫;李衛(wèi)國;張文華;王新宇;徐淑軍;李新鋼;;經(jīng)眶上外側(cè)入路切除前顱窩底腦膜瘤的臨床分析[J];中華神經(jīng)外科雜志;2016年01期

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