本文關鍵詞：超聲造影、血流動力學參數(shù)、微血管密度在前列腺癌與慢性前列腺炎中的診斷價值　出處：《廣西醫(yī)科大學》2017年碩士論文　論文類型：學位論文

  更多相關文章： 血流動力學參數(shù) 微血管密度 超聲造影參數(shù) 前列腺癌 Gleason評分

【摘要】：目的:評價微血管密度(microvessel density,MVD)、超聲造影參數(shù)、血流動力學參數(shù)在前列腺癌(prostatic cancer,PCa)與慢性前列腺炎(chronic prostatitis,CP)中的差異及相關性,為PCa與CP的診斷及鑒別診斷、PCa的預后提供幫助。方法:對廣西醫(yī)科大學第一附屬醫(yī)院2014-2015年泌尿外科收治入選的前列腺病患68例行前列腺經(jīng)直腸超聲(Transrectal Ultrasonography,TRUS),獲取血流動力學參數(shù);前列腺經(jīng)直腸超聲造影(contrast enhanced transrectal ultrasound,CETRUS),獲取造影參數(shù);超聲引導下穿刺活檢或手術明確病理類型及格里森(Gleason)評分;進行免疫組化MVD的測定。比較PCa組與CP組、PCa中Gleason評分≤3+4組與Gleason評分≥4+3組的血流動力學、MVD、超聲造影參數(shù)的差異;研究PCa中MVD與血流動力學參數(shù)、超聲造影參數(shù)的相關性。結(jié)果:病理證實前列腺癌患者44例,CP患者24例。PCa組與CP組中的收縮期峰值血流速度(Velocity of flow in systolic,Vs)、阻力指數(shù)(Resistance Index,RI)、初始強度(Basic intensity,B)、曲線下面積(Area under the curve,AUC)、峰值強度(Peak Intensity,PI)、MVD差異均有統(tǒng)計學意義(P0.05);PCa中Gleason評分≥4+3組28例,Gleason評分≤3+4組16例,兩組間Vs、RI、MVD差異有統(tǒng)計學意義(P0.05);PCa中Vs、RI、AUC與MVD具有正相關(P0.05),r分別為0.578、0.688、0.737。結(jié)論:血流動力學、超聲造影參數(shù)、微血管密度為PCa與CP的診斷與鑒別診斷提供幫助;前列腺癌中超聲造影、血流動力學參數(shù)可較好的反映微血管密度;血流動力學參數(shù)、微血管密度對PCa患者預后的判斷有一定價值。
[Abstract]:Objective: to evaluate the microvessel density (MVDV) of microvessel density (MVD), and to evaluate the parameters of contrast-enhanced ultrasound (CEUs). Hemodynamic parameters were found in prostatic cancer PCA and chronic prostatitis prostatitis. The difference and correlation between PCa and CP were the diagnosis and differential diagnosis of PCa and CP. The prognosis of PCa. Methods: 68 patients admitted to urology department in the first affiliated Hospital of Guangxi Medical University from 2014 to 2015 underwent transrectal ultrasound (TUS). Transrectal Ultrasonography. Trust to obtain hemodynamic parameters; Contrast enhanced transrectal ultrasound trust was used to obtain the parameters of prostate contrast transrectal ultrasound. Ultrasound-guided biopsy or surgery was performed to determine the pathological type and Gleason score. To compare the hemodynamics of Gleason score 鈮，

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