本文關(guān)鍵詞：嬰幼兒喂養(yǎng)行為與其貧血關(guān)系的出生隊(duì)列研究　出處：《浙江大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 嬰幼兒 全母乳喂養(yǎng) 輔食 貧血 血紅蛋白

【摘要】：不少研究證實(shí)嬰幼兒的喂養(yǎng)行為如全母乳喂養(yǎng)時(shí)間長(zhǎng)短,輔食添加年齡與其血紅蛋白濃度和貧血患病風(fēng)險(xiǎn)緊密相關(guān)。不過(guò)這些研究得出的結(jié)果并不一致,而且大部分研究都是在西方或歐洲國(guó)家進(jìn)行的。因此需要更多的大型前瞻性研究,特別是在亞洲國(guó)家進(jìn)行的研究,來(lái)進(jìn)一步闡明這一關(guān)鍵問(wèn)題。本研究的主要目的是基于我國(guó)的一個(gè)大型出生隊(duì)列研究——嘉興出生隊(duì)列來(lái)探究嬰兒全母乳喂養(yǎng)時(shí)長(zhǎng)、輔食添加時(shí)間及種類與其貧血間的關(guān)系。本研究從嘉興出生隊(duì)列研究入手,從中篩選出提供了基本信息、詳細(xì)母乳喂養(yǎng)和輔食添加信息以及其他一些測(cè)量學(xué)數(shù)據(jù)的嬰兒。采用logistic回歸模型來(lái)評(píng)估全母乳喂養(yǎng)時(shí)長(zhǎng)、輔食添加時(shí)間與嬰幼兒在12月齡和48-71月齡時(shí)貧血患病風(fēng)險(xiǎn)的關(guān)系;采用線性回歸模型來(lái)衡量這兩個(gè)因素與嬰幼兒血紅蛋白濃度的關(guān)系。本研究主要結(jié)果如下:(1)在探究全母乳喂養(yǎng)時(shí)長(zhǎng)與貧血關(guān)系的研究中,共有25,393名嬰兒納入12月齡的分析,32,658名幼兒納入48-71月齡的分析。分析發(fā)現(xiàn)與小于3個(gè)月的全母乳喂養(yǎng)相比,多6個(gè)月的全母乳喂養(yǎng)與嬰兒在12月齡時(shí)的貧血患病風(fēng)險(xiǎn)增加顯著相關(guān),校正OR值為1.15(95%CI:1.02,1.29),在48-71月齡時(shí)僅為邊緣顯著相關(guān),校正OR值為1.13(95%CI:0.99,1.29)。不過(guò),不管是12月齡的嬰兒還是48-71月齡的幼兒,≥6個(gè)月的全母乳喂養(yǎng)均與血紅蛋白濃度的降低顯著相關(guān)。(2)在探究輔食添加時(shí)間及種類與貧血關(guān)系的研究中,共有18,446名48-71月齡幼兒納入分析。分析發(fā)現(xiàn)與在6月齡及以后添加輔食相比,在3-6月齡添加輔食與貧血風(fēng)險(xiǎn)增加顯著相關(guān),校正OR值為1.14(95%CI:1.01-1.28);與血紅蛋白濃度降低也顯著相關(guān),校正平均差為-0.84g/L(95%CI:-1.33,-0.35)。在不同類別的輔食中,這種相關(guān)關(guān)系主要存在于植物性輔食如面包/烤饅頭/掛面,爛面/餅干,豆腐等。綜上所述,全母乳喂養(yǎng)時(shí)間過(guò)長(zhǎng)(≥6個(gè)月)或添加輔食過(guò)早(3-6月齡時(shí)添加)均與嬰幼兒貧血風(fēng)險(xiǎn)的增加以及血紅蛋白濃度的降低有關(guān)。這與WHO現(xiàn)行推薦的在嬰兒前6個(gè)月進(jìn)行全母乳喂養(yǎng),在6月齡時(shí)添加輔食相一致。因此,在進(jìn)行6個(gè)月的全母乳喂養(yǎng)后,父母應(yīng)注意給其孩子補(bǔ)充充足的鐵來(lái)源來(lái)預(yù)防貧血的發(fā)生。
[Abstract]:Many studies confirm that infant feeding behavior is like breastfeeding time. The age of complementary feeding is closely related to the hemoglobin concentration and the risk of anemia. However, the results of these studies are not consistent, and most of the studies are conducted in Western or European countries. Therefore, more large prospective studies, especially in Asian countries, are needed to further clarify this key issue. The purpose of this study is based on a large birth cohort study in Jiaxing, the birth cohort in China, to explore the relationship between the duration of infant breastfeeding, the time and type of complementary food and its anemia. From the birth cohort study in Jiaxing, we screened out infants who provided basic information, detailed information about breastfeeding and complementary feeding, and some other surveying data. Logistic regression model was used to evaluate the relationship between the duration of full breastfeeding, the time of complementary feeding and the risk of anemia in infants at 12 month old and 48-71 months of age. The relationship between these two factors and the hemoglobin concentration of infants was measured by a linear regression model. The main results of this study are as follows: (1) in the study of the relationship between the duration of total breastfeeding and anemia, a total of 25393 infants were included in the analysis of 12 month old, and 32658 children were included in the analysis of 48-71 months old. Compared with less than 3 months of full breastfeeding found, more than 6 months of full breastfeeding and infant anemia in December at the age of increased risk was significantly related to OR correction value of 1.15 (95%CI:1.02,1.29), at 48-71 months of age was significantly related to the edge correction value of OR was 1.13 (95%CI:0.99,1.29). However, whether the December age babies or children 48-71 months of age, more than 6 months of full breastfeeding and lower hemoglobin concentrations were significantly correlated. (2) in the study of the relationship between the time and type of supplementary food and the relationship between anemia and anemia, a total of 18446 children of 48-71 months of age were included in the analysis. It was found that the supplement of complementary foods at 3-6 months old was significantly associated with the risk of anemia. The corrected OR value was 1.14 (95%CI:1.01-1.28), which was also significantly correlated with the decrease of hemoglobin concentration. The corrected mean difference was -0.84g/L (95%CI:-1.33, -0.35). In the different types of food, the correlation is mainly in the vegetable food such as bread / roast steamed bread / noodle, rotten surface / biscuit, tofu and so on. To sum up, the whole milk feeding time is too long (over 6 months) or complementary early (add 3-6 months) were associated with increased risk of infant anemia and hemoglobin concentration decreased. This is in accordance with WHO's present recommendation for full breastfeeding in the first 6 months of the baby and the addition of supplementary food at 6 month old. Therefore, after 6 months of full breastfeeding, parents should pay attention to giving their children a sufficient source of iron to prevent the occurrence of anemia.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R725.5

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