本文選題：莪術(shù)油 + 微囊��； 參考：《中草藥》2017年15期

【摘要】：目的研究噴霧干燥法制備莪術(shù)油微囊的最佳處方及最佳工藝。方法以微囊粒徑、微囊形態(tài)、包埋率為考察指標(biāo),采用單因素實(shí)驗(yàn)對(duì)囊材配比、芯材與囊材比、干物質(zhì)用量、附加劑PEG6000用量、乳化速度、乳化時(shí)間、進(jìn)風(fēng)溫度、進(jìn)料功率進(jìn)行了研究,篩選出莪術(shù)油微囊的最佳處方及最佳工藝。結(jié)果噴霧干燥法制備莪術(shù)油微囊的最佳處方為阿拉伯膠-明膠(1.0∶1.0),芯材-囊材(0.30∶1.0),附加劑PEG6000用量2%,干物質(zhì)用量20%;最佳工藝為乳化速度10 600 r/min,乳化時(shí)間9 min,進(jìn)風(fēng)溫度160℃,進(jìn)料功率6%。根據(jù)最佳實(shí)驗(yàn)條件制得的微囊較圓整,表面致密,粒徑分布均勻,多數(shù)集中在1.0~2.5μm,且呈較好的正態(tài)分布,平均粒徑1.913μm,包埋率可達(dá)75.4%。結(jié)論本實(shí)驗(yàn)采用的方法可增加莪術(shù)油的穩(wěn)定性,掩蓋其不良?xì)馕?且藥物利用率較高,重復(fù)性好。
[Abstract]:Objective to study the optimum formulation and process of preparation of turmeric oil microcapsules by spray drying. Methods the particle size, morphology and embedding rate of microcapsules were used as the index. The ratio of core material to capsule material, dry matter dosage, PEG6000 dosage, emulsifying speed, emulsifying time and inlet air temperature were measured by single factor experiment. The optimum prescription and process of turmeric oil microencapsulation were obtained by studying the feed power of zedoary turmeric oil. Results the optimum conditions for preparation of turmeric oil microcapsules by spray drying were as follows: Arabic gelatin 1.0: 1.0, core material and capsule 0.30: 1.0, additive PEG6000 2, dry matter 20, emulsifying speed 10 600 r / min, emulsifying time 9 min, air inlet temperature 160 鈩，

本文編號(hào)：1857929