本文選題：分子印跡聚合物　切入點：可逆加成-斷裂鏈轉移自由基聚合　出處：《西安電子科技大學》2011年碩士論文

【摘要】：本論文研究了將可逆加成—斷裂鏈轉移自由基聚合(Reversible Addition- Fragmentation Chain Transfer Radical polymerization,RAFT polymerization)與沉淀聚合相結合,制備四環(huán)素分子印跡微球的方法。首先進行了二硫代苯甲酸異丙苯基酯(Cumyl Dithiobenzoate,CDB)的合成。以合成的CDB為鏈轉移試劑,四環(huán)素為模板分子,甲基丙烯酸為功能單體,應用RAFT沉淀聚合法,結合分子印跡技術,合成了四環(huán)素分子印跡聚合物微球。通過氧瓶燃燒實驗測定聚合物中硫元素的含量,結果證明鏈轉移試劑基團(CDB)存在于聚合物結構中。通過平衡吸附實驗測定了印跡聚合物和非印跡聚合物對四環(huán)素的吸附量。以合成的印跡聚合物作為色譜固定相,用液相色譜法對其識別能力進行了評價,并考察了不同流動相對其保留行為的影響。
[Abstract]:In this paper, the reversible addition-break chain transfer radical polymerization (Reversible addition-Fragmentation Chain Transfer Radical polymerization) and precipitation polymerization have been studied. Preparation of tetracycline molecularly imprinted microspheres. Firstly, the synthesis of Cumyl Dithiobenzoate CDBs was carried out. The synthesized CDB was used as chain transfer reagent, tetracycline as template molecule and methacrylic acid as functional monomer. Tetracycline molecularly imprinted polymer microspheres were synthesized by RAFT precipitation polymerization and molecular imprinting technique. The results showed that the chain transfer reagent group CDB existed in the polymer structure. The adsorption amount of tetracycline by imprinted and non-imprinted polymers was determined by equilibrium adsorption experiment. The imprinted polymer was used as the chromatographic stationary phase. Its recognition ability was evaluated by liquid chromatography, and the effect of different flow on its retention behavior was investigated.
【學位授予單位】：西安電子科技大學
【學位級別】：碩士
【學位授予年份】：2011
【分類號】：O631.3

【引證文獻】

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1 崔強;王巖;管清帥;宋曉麗;白文營;;砜嘧磺隆分子印跡單分散聚合物微球的制備及表征[J];農藥;2013年07期

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1 崔強;砜嘧磺隆分子印跡單分散聚合物微球的研究[D];吉林農業(yè)大學;2013年

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本文編號：1682729