本文關(guān)鍵詞：CO2激光聯(lián)合平陽霉素治療喉接觸性肉芽腫的療效分析，，由筆耕文化傳播整理發(fā)布。

CO2激光聯(lián)合平陽霉素治療喉接觸性肉芽腫的療效分析

Clinical efficacy of CO2 laser combined with pingyangmycin for laryngeal contact granuloma

[1] [2] [3]

Gou Xue, Zhu Jiang, Li Qinghui （Department of Otolaryngology, the First Affiliated Hospital of Chongqing Medical University;Department of Otolaryngology, Central Hospital of Ji

[1]重慶醫(yī)科大學(xué)附屬第一醫(yī)院耳鼻咽喉科,重慶400016; [2]重慶市江津區(qū)中心醫(yī)院耳鼻咽喉科,重慶402260

文章摘要：目的：觀察CO2激光聯(lián)合平陽霉素的方法治療喉接觸性肉芽腫的臨床療效。方法：回顧性分析我院2011年1月至2012年12月確診的18例喉接觸性肉芽腫患者的臨床資料。18例患者于我院共有22次治療史。9例次采用CO2激光手術(shù)聯(lián)合平陽霉素治療,另13例次采用單純CO2激光手術(shù)治療,將所有病例根據(jù)治療方法分為2組（CO2激光聯(lián)合平陽霉素組與CO2激光組）。術(shù)后隨訪6個(gè)月以上。結(jié)果：CO2激光聯(lián)合平陽霉素組1次手術(shù)治愈9例,治愈率為100.0%。CO2激光組1次手術(shù)治愈7例,6例術(shù)后復(fù)發(fā),治愈率為53.8%,兩者比較CO2激光聯(lián)合平陽霉素1次治療復(fù)發(fā)率低于單純CO2激光手術(shù)（P〈0.05）。結(jié)論：喉接觸性肉芽腫有強(qiáng)烈的復(fù)發(fā)傾向,其發(fā)生和術(shù)后復(fù)發(fā)的原因可能是大量纖維細(xì)胞、血管增生,對于多次復(fù)發(fā)者,采用CO2激光聯(lián)合平陽霉素的方法,可使血管閉塞,肉芽腫無法生長,明顯降低復(fù)發(fā)率。

Abstr：Objective：To observe the clinical efficacy of CO2 laser combined with pingyangmycin for laryngeal contact granuloma. Methods：Clinical data of 18 cases of laryngeal contact granuloma diagnosed from January 2011 to December 2012 in our hospital were retrospectively analyzed. All 18 patients had 22 times treatment history. Among them,9 patients were treated by CO2 laser operation combined with pingyangmycin（group 1） while 13 patients were treated by single CO2 laser operation（group 2）. All patients were followed up over 6 months after the operation. Results：The one-time curative rate was 100% in group 1 and was 53.8% in group 2. 7 cases were cured and 6 cases experienced recurrence. The relapse rate of CO2 laser operation combined with pingyangmycin was lower than that of single CO2 laser operation （P〈0.05）. Conclusion ：Laryngeal contact granuloma has a strong tendency to recur. The reason of occurrence and recurrence may relate with a large number of fiber cells and vascular proliferation. For recurrent patients, CO2 laser combined with pingyangmycin leads to vascular occlusion and granuloma growth inhibition ;therefore can significantly reduce the recurrence rate.

文章關(guān)鍵詞：

Keyword：:laser larynx granuloma pingyangmycin

課題項(xiàng)目：國家臨床重點(diǎn)�？平ㄔO(shè)資助項(xiàng)目（編號：衛(wèi)辦醫(yī)政函[2012]649號）;重慶市醫(yī)學(xué)科研重點(diǎn)項(xiàng)目經(jīng)費(fèi)資助項(xiàng)目（編號2013-1-004）.

  本文關(guān)鍵詞：CO2激光聯(lián)合平陽霉素治療喉接觸性肉芽腫的療效分析，由筆耕文化傳播整理發(fā)布。