正念減壓療法對非霍奇金淋巴瘤患者創(chuàng)傷后成長的效果研究
發(fā)布時間：2019-06-21 18:57
【摘要】：目的探討正念減壓療法對促進正在化療的非霍奇金淋巴瘤患者的創(chuàng)傷后成長水平,減輕患者的疲勞,改善睡眠質(zhì)量的效果。方法選取2015年11月至2016年4月在鄭州大學(xué)第一附屬醫(yī)院腫瘤科住院化療的非霍奇金淋巴瘤患者96例,便利分配到兩個腫瘤病區(qū)中各48例,采用拋硬幣法將兩個病區(qū)分為對照組、試驗組。對照組接受醫(yī)院常規(guī)的護理,組在常規(guī)護理基礎(chǔ)上,進行每周1次、共8次的正念減壓訓(xùn)練。采用中文版創(chuàng)傷后成長量表(Posttraumatic Growth Inventory,PTGI)、Piper疲乏修訂量表(The Revised Piper Fatigue Scale,PFS-R)、匹茲堡睡眠質(zhì)量指數(shù)(Pittsburgh Sleep Quality Index,PSQI)量表,于干預(yù)前(T1)、干預(yù)后(T2)以及干預(yù)后3個月(T3)對患者進行測評,評估干預(yù)效果。采用Excel2016錄入數(shù)據(jù),SPSS18.0進行統(tǒng)計分析,計量資料采用均數(shù)±標(biāo)準(zhǔn)差,計數(shù)資料采用頻數(shù)、百分比(n%),兩組基線資料比較采用t-test或者χ2檢驗,重復(fù)測量方差分析比較兩組的差異,檢驗干預(yù)的效應(yīng)采用Cohen’s D。結(jié)果1)本研究按照納入、排除標(biāo)準(zhǔn)對鄭州大學(xué)第一附屬醫(yī)院腫瘤科首次化療的非霍奇金淋巴瘤患者96例進行干預(yù),最后完成所有結(jié)果評價的有效樣本91例,完成率為94.8%。2)干預(yù)前兩組研究變量差異無統(tǒng)計學(xué)意義,8周干預(yù)后:(1)兩組患者的PTGI總分均有升高,并且PTGI總分時間效應(yīng)、時間與組別的交互效應(yīng)均有統(tǒng)計學(xué)意義(P0.001)。然而,新的可能性(F=3.57,P=0.05)、精神變化(F=2.43,P=0.11)沒有組別效應(yīng)以及組別和時間的交互效應(yīng)。(2)重復(fù)測量方差分析顯示,試驗組和對照組感覺方面、行為方面、情緒方面以及總疲勞得分干預(yù)主效應(yīng)有統(tǒng)計學(xué)意義(P0.05);兩組感覺方面、情緒方面、總疲勞得分時間主效應(yīng)有統(tǒng)計學(xué)意義(P0.05),即感覺方面、情緒方面以及總疲勞隨時間的變化而變化;感覺方面、情緒方面、行為方面以及總疲勞得分的干預(yù)因素與時間因素存在交互作用(P0.05)。(3)睡眠質(zhì)量、入睡時間、睡眠時間、睡眠效率以及睡眠總分的組間效應(yīng)差異有統(tǒng)計學(xué)意義(P0.05),睡眠質(zhì)量、入睡時間、睡眠時間以及睡眠總分時間效應(yīng)差異有統(tǒng)計學(xué)意義(P0.05),睡眠質(zhì)量、睡眠時間、睡眠障礙、睡眠總分交互效應(yīng)差異有統(tǒng)計學(xué)意義。3)干預(yù)結(jié)束時,干預(yù)組除行為方面、日間功能障礙Cohen’s D0.5,其余均大于0.5,表明8周正念減壓療法(Mindfullness-Based Stress Reduction,MBSR)干預(yù)措施在結(jié)束時,能達(dá)到各個變量中等及中等及以上效應(yīng)。4)干預(yù)結(jié)束后3個月,對個人力量、欣賞生活、行為方面、日間功能障礙Cohen’s D0.5,干預(yù)持續(xù)效應(yīng)為中等,對與他人的關(guān)系、感覺方面、情緒方面、總疲勞、睡眠質(zhì)量、睡眠時間、睡眠效率以及入睡時間的干預(yù)效應(yīng)很大,Cohen’s D均大于1.2,對PTGI總分干預(yù)效應(yīng)巨大,Cohen’s D為2.0。結(jié)論8周正念減壓療法干預(yù)措施以及效果評價表明,作為非藥物治療的方法能夠有效促進非霍奇金淋巴瘤患者的創(chuàng)傷后成長,減輕化療期的疲乏,改善睡眠質(zhì)量,并且在較長時間內(nèi)(3個月)持續(xù)效應(yīng)很大,患者積極接受正念減壓療法干預(yù),能夠從中獲益良多。
[Abstract]:Objective To study the effect of stress-reduction therapy on the post-traumatic growth of patients with non-Hodgkin's lymphoma undergoing chemotherapy, to reduce the fatigue of patients and to improve the quality of sleep. Methods 96 patients with non-Hodgkin's lymphoma were selected from November 2015 to April 2016 at the First Affiliated Hospital of Zhengzhou University. The control group received the routine care of the hospital, and on the basis of routine nursing, the control group conducted once a week for 8 times, and the training was carried out in a total of 8 times. Patients were assessed using the Chinese version of Post-traumatic Growth Inventory (PTGI), the Piper Fatigue Revision Scale (PFS-R), the Pittsburgh Sleep Quality Index (PSQI) scale, the pre-intervention (T1), post-intervention (T2), and 3 months after intervention (T3), Evaluate the effect of the intervention. The data of Excel2016 and SPSS18.0 were used for statistical analysis. The standard deviation of the mean number was used for the measurement data, and the frequency and the percentage (n%) were used for counting the data. The difference between the two groups was compared with the two groups of baseline data by the t-test or the second test, and the variance of the two groups was compared with the analysis of variance. The effect of the test intervention was Cohen's D. Results 1) The study included 96 cases of non-Hodgkin's lymphoma who received the first chemotherapy in the first affiliated hospital of Zhengzhou University in accordance with the inclusion and exclusion criteria, and the effective sample of all the results was completed in 91 cases. The completion rate was 94.8%.2) There was no statistical significance in the difference between the two groups before the intervention, and after 8 weeks of intervention: (1) the total score of PTGI in the two groups was increased, and the time effect of the total score of the PTGI was statistically significant (P 0.001). However, the new possibilities (F = 3.57, P = 0.05), mental changes (F = 2.43, P = 0.11) had no group effects and group and time interaction effects. (2) The results of variance analysis showed that there was a significant difference between the two groups of sensory, emotional and total fatigue scores (P0.05). I. e., sensory, emotional, and total fatigue change with time; sensory, emotional, behavioral, and total fatigue scores have an interaction with time factors (p0.05). (3) The effects of sleep quality, sleep time, sleep time, sleep efficiency and sleep total score were of statistical significance (P0.05), sleep quality, sleep time, sleep time and time effect of sleep total score (P0.05), and sleep quality. The effect of sleep time, sleep disturbance and sleep total score is of statistical significance. At the end of the intervention, the intervention group, in addition to the behavior, the daytime dysfunction Cohen's D.5, the balance of which is greater than 0.5, indicates that the intervention of the 8-week positive-reading stress reduction (MBSR) intervention is at the end of the intervention. can reach the effects of middle and middle and above effects of various variables.4)3 months after the intervention, for personal power, to enjoy the life and the behavior, the daytime dysfunction Cohen's D.5, the intervention sustained effect is middle, the relationship with the other, the feeling aspect, the emotional aspect, the total fatigue, The effects of sleep quality, sleep time, sleep efficiency and time of sleep are significant. Cohen's D is more than 1.2, and the intervention effect on the total score of PTGI is huge. Cohen's D is 2.0. Conclusion 8-week treatment of non-Hodgkin's lymphoma can effectively promote the post-traumatic growth of non-Hodgkin's lymphoma, reduce the fatigue of the chemotherapy period and improve the sleep quality. And for a long period of time (3 months), the effect of the continuous effect is very large, and the patient is actively receiving the intervention of the positive and negative pressure therapy, so that the patient can benefit from it.
【學(xué)位授予單位】：鄭州大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R473.73
[Abstract]:Objective To study the effect of stress-reduction therapy on the post-traumatic growth of patients with non-Hodgkin's lymphoma undergoing chemotherapy, to reduce the fatigue of patients and to improve the quality of sleep. Methods 96 patients with non-Hodgkin's lymphoma were selected from November 2015 to April 2016 at the First Affiliated Hospital of Zhengzhou University. The control group received the routine care of the hospital, and on the basis of routine nursing, the control group conducted once a week for 8 times, and the training was carried out in a total of 8 times. Patients were assessed using the Chinese version of Post-traumatic Growth Inventory (PTGI), the Piper Fatigue Revision Scale (PFS-R), the Pittsburgh Sleep Quality Index (PSQI) scale, the pre-intervention (T1), post-intervention (T2), and 3 months after intervention (T3), Evaluate the effect of the intervention. The data of Excel2016 and SPSS18.0 were used for statistical analysis. The standard deviation of the mean number was used for the measurement data, and the frequency and the percentage (n%) were used for counting the data. The difference between the two groups was compared with the two groups of baseline data by the t-test or the second test, and the variance of the two groups was compared with the analysis of variance. The effect of the test intervention was Cohen's D. Results 1) The study included 96 cases of non-Hodgkin's lymphoma who received the first chemotherapy in the first affiliated hospital of Zhengzhou University in accordance with the inclusion and exclusion criteria, and the effective sample of all the results was completed in 91 cases. The completion rate was 94.8%.2) There was no statistical significance in the difference between the two groups before the intervention, and after 8 weeks of intervention: (1) the total score of PTGI in the two groups was increased, and the time effect of the total score of the PTGI was statistically significant (P 0.001). However, the new possibilities (F = 3.57, P = 0.05), mental changes (F = 2.43, P = 0.11) had no group effects and group and time interaction effects. (2) The results of variance analysis showed that there was a significant difference between the two groups of sensory, emotional and total fatigue scores (P0.05). I. e., sensory, emotional, and total fatigue change with time; sensory, emotional, behavioral, and total fatigue scores have an interaction with time factors (p0.05). (3) The effects of sleep quality, sleep time, sleep time, sleep efficiency and sleep total score were of statistical significance (P0.05), sleep quality, sleep time, sleep time and time effect of sleep total score (P0.05), and sleep quality. The effect of sleep time, sleep disturbance and sleep total score is of statistical significance. At the end of the intervention, the intervention group, in addition to the behavior, the daytime dysfunction Cohen's D.5, the balance of which is greater than 0.5, indicates that the intervention of the 8-week positive-reading stress reduction (MBSR) intervention is at the end of the intervention. can reach the effects of middle and middle and above effects of various variables.4)3 months after the intervention, for personal power, to enjoy the life and the behavior, the daytime dysfunction Cohen's D.5, the intervention sustained effect is middle, the relationship with the other, the feeling aspect, the emotional aspect, the total fatigue, The effects of sleep quality, sleep time, sleep efficiency and time of sleep are significant. Cohen's D is more than 1.2, and the intervention effect on the total score of PTGI is huge. Cohen's D is 2.0. Conclusion 8-week treatment of non-Hodgkin's lymphoma can effectively promote the post-traumatic growth of non-Hodgkin's lymphoma, reduce the fatigue of the chemotherapy period and improve the sleep quality. And for a long period of time (3 months), the effect of the continuous effect is very large, and the patient is actively receiving the intervention of the positive and negative pressure therapy, so that the patient can benefit from it.
【學(xué)位授予單位】：鄭州大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R473.73
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