發(fā)布時(shí)間：2019-04-07 15:35

【摘要】：目的探討血清降鈣素原(PCT)、超敏C反應(yīng)蛋白(hs-CRP)、白細(xì)胞計(jì)數(shù)(WBC)、中性粒細(xì)胞百分比(NEU%)在不同致病菌感染所致膿毒癥早期診斷的臨床價(jià)值,為膿毒癥患者提供風(fēng)險(xiǎn)評(píng)估。方法回顧性分析2013年10月至2015年10月在徐州市中醫(yī)院重癥醫(yī)學(xué)科(ICU)就診的血流感染致膿毒癥117例患者的臨床資料,所有患者在抗菌藥物使用之前進(jìn)行血培養(yǎng),根據(jù)血培養(yǎng)結(jié)果分為革蘭陽性菌(G+菌)組和革蘭陰性菌(G-菌)組,所有患者均進(jìn)行PCT、hs-CRP、WBC、NEU%檢測(cè),分析兩組患者檢測(cè)結(jié)果的差異,評(píng)價(jià)PCT與急性生理與慢性健康狀況評(píng)分系統(tǒng)Ⅱ評(píng)分(APACHE-Ⅱ評(píng)分)和序貫器官衰竭評(píng)分(SOFA評(píng)分)的相關(guān)性。結(jié)果 117例膿毒血癥的患者中G+菌組78例,G-菌組39例;與G+菌組比較,G-菌組PCT檢測(cè)變化明顯,差異有統(tǒng)計(jì)學(xué)意義(P0.05),而hs-CRP、WBC、NEU檢測(cè)結(jié)果變化不大(P0.05);G-菌組血清PCT與SOFA評(píng)分呈正相關(guān)(r=0.536,P0.05),而與APACHE-Ⅱ評(píng)分無相關(guān)性(P0.05);G+菌組血清PCT與APACHE-Ⅱ評(píng)分、SOFA評(píng)分均無相關(guān)性(P0.05)。結(jié)論 PCT在不同致病菌感染所致膿毒癥的早期鑒別診斷和預(yù)后監(jiān)測(cè)中有一定價(jià)值,且對(duì)G-菌更靈敏。
[Abstract]:Objective to investigate the clinical value of serum procalcitonin (PCT), hypersensitive C-reactive protein (hs-CRP) and leukocyte count (WBC), neutrophil percentage (NEU%) in early diagnosis of sepsis caused by different pathogenic bacteria infection. Provides risk assessment for sepsis patients. Methods the clinical data of 117 patients with sepsis caused by blood flow infection were retrospectively analyzed from October 2013 to October 2015 in the Department of critical Medicine of Xuzhou traditional Chinese Medicine Hospital (ICU). All patients were cultured before the use of antibiotics. According to the results of blood culture, they were divided into Gram-positive bacteria (G-bacteria) group and Gram-negative bacteria (G-bacteria) groups. All patients were detected by PCT,hs-CRP,WBC,NEU%, and the difference between the two groups was analyzed. To evaluate the correlation between PCT and acute physiological and chronic health status score 鈪，

本文編號(hào)：2454167