【摘要】：目的:探討釓貝葡胺(Gd-BOPTA)一站式雙功能對(duì)比MR成像(DFCE-MRI)對(duì)于肝細(xì)胞癌(HCC)診斷的價(jià)值。方法:對(duì)117例肝臟局灶性病變(FLL)患者行Gd-BOPTA一站式DFCE-MRI,包括:(1)MR平掃;(2)彌散加權(quán)成像(DWI);(3)Gd-BOPTA多期增強(qiáng);(4)肝膽期掃描,比較Ⅰ((1))、Ⅱ((1)+(3))、Ⅲ((1)+(2)+(3))、Ⅳ((1)+(2)+(3)+(4),即:一站式DFCE-MRI)等四種掃描方案對(duì)于FLL的檢出率和對(duì)HCC診斷的敏感性、特異性、準(zhǔn)確性。結(jié)果:Ⅰ~Ⅳ四種掃描方案對(duì)FLL檢出率分別為74.2%、87.4%、98.7%和98.7%,四者差異有統(tǒng)計(jì)學(xué)意義(P0.05),方案Ⅰ檢出率明顯低于其他三種增強(qiáng)掃描方案;Ⅱ~Ⅳ三種增強(qiáng)掃描方案對(duì)HCC診斷的敏感度、特異度、準(zhǔn)確度分別為76.2%、70.1%和73.1%,92.9%、82.9%和85.5%,92.9%、90.5%和91.2%,三者差異有統(tǒng)計(jì)學(xué)意義(P0.05),且以方案Ⅳ準(zhǔn)確度最高。結(jié)論:Gd-BOPTA一站式DFCE-MRI對(duì)FLL檢出率以及對(duì)HCC診斷的準(zhǔn)確度優(yōu)于其他掃描方案,可以作為肝細(xì)胞癌鑒別診斷的優(yōu)選MR掃描方案。
[Abstract]:Objective: to evaluate the value of gadolinium meglumine (Gd-BOPTA) one-stop dual-function contrast MR imaging (DFCE-MRI) in the diagnosis of hepatocellular carcinoma (HCC). Methods: one stop Gd-BOPTA DFCE-MRI, was performed in 117 patients with focal hepatic lesions (FLL) including: (1) MR plain scan; (2) diffusion-weighted (DWI); (3) Gd-BOPTA multiphase enhancement; (4) hepatobiliary phase scan. The detection rate of FLL and the sensitivity, specificity and accuracy of four scanning protocols 鈪，

本文編號(hào)：2201353