發(fā)布時間：2018-08-23 09:35

【摘要】：目的研究乳腺癌化療后患者的人格和生活質(zhì)量變化以及與癌因性疲乏相關(guān)性。方法研究對象選取上海市腫瘤醫(yī)院和中山醫(yī)院2013年12月到2014年7月間接受化療治療的乳腺癌患者66例,應(yīng)用橫斷面調(diào)查方法,采用一般資料問卷、癌因性疲乏量表(CFS)、癥狀自評量表(SCL-90)及艾森克人格問卷簡式量表(EPQ-RSC)對患者進(jìn)行調(diào)查,分析化療對患者的CFS、SCL-90及EPQ-RSC評分影響,并用Spearman相關(guān)分析其相關(guān)性。結(jié)果所有患者的疲乏總分為(35.45±7.21)分,處于中度水平;神經(jīng)質(zhì)和精神質(zhì)評分均名高于國內(nèi)常模標(biāo)準(zhǔn)得分(P0.05);化療后所有患者的SCL-90總分和各因子得分均明顯高于化療前(P0.01);神經(jīng)質(zhì)與疲乏總分、軀體疲乏、心理疲乏、認(rèn)知疲乏均存在顯著正相關(guān)(P0.01),與SCL-90總分、抑郁、焦慮和恐怖因子呈正相關(guān)(P0.01);精神質(zhì)與情感疲乏存在顯著正相關(guān)(P0.01);內(nèi)-外向性與疲乏總分、心理疲乏均存在顯著負(fù)相關(guān)(P0.01),與抑郁、焦慮和恐怖因子呈負(fù)相關(guān)(P0.01)。結(jié)論癌因性疲乏較普遍存在于乳腺癌化療患者,化療在一定程度上危害患者心理健康。癌因性疲乏可能受人格因素影響,而心理健康與人格也可能存在一定相關(guān)性。
[Abstract]:Objective to study the changes of personality and quality of life (QOL) in patients with breast cancer after chemotherapy. Methods 66 patients with breast cancer treated by indirect chemotherapy from December 2013 to July 2014 were selected from Shanghai Cancer Hospital and Zhongshan Hospital. The patients were investigated by (CFS), symptom Checklist (SCL-90) and Eysenck Personality questionnaire (EPQ-RSC). The effects of chemotherapy on CFSS-SCL-90 and EPQ-RSC scores were analyzed. The correlation between SCL-90 and EPQ-RSC was analyzed by Spearman correlation. Results the total score of fatigue in all patients was (35.45 鹵7.21), which was at the moderate level. The scores of neuroticism and psychoticism were higher than those of the national norm (P0.05); the total score of SCL-90 and the scores of all factors after chemotherapy were significantly higher than those before chemotherapy (P0.01); the total scores of neuroticism and fatigue, somatic fatigue, psychological fatigue were significantly higher than those before chemotherapy (P0.01). There was a significant positive correlation between cognitive fatigue and SCL-90, depression, anxiety and phobic factors (P0.01), significant positive correlation between psychoticism and affective fatigue (P0.01), significant negative correlation between introverse-extroversion and total score of fatigue, psychological fatigue (P0.01), and significant negative correlation between mental fatigue and depression (P0.01). There was a negative correlation between anxiety and phobic factors (P0.01). Conclusion Carcinomatous fatigue is common in patients with breast cancer and chemotherapy is harmful to their mental health to some extent. Cancer-related fatigue may be influenced by personality factors, and mental health may be related to personality.
【作者單位】： 上海市交通大學(xué)醫(yī)學(xué)院附屬精神衛(wèi)生中心;
【分類號】：R473.73

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本文編號：2198644