【摘要】：目的探討心臟磁共振(CMR)特征追蹤(CMR-FT)技術(shù)定量評價肥厚型心肌病(HCM)患者心肌形變的價值。方法對16例HCM患者(HCM組)及18名健康志愿者(正常對照組)采用CMR-FT技術(shù)行CMR檢查。比較兩組間左心室舒張末期容積(LVEDV)、收縮末期容積(LVESV)、左心室射血分數(shù)(LVEF)、左心室質(zhì)量(LVMASS)及左心室心肌整體徑向應變(RS)、環(huán)向應變(CS)的差異。并分析HCM患者各節(jié)段室壁厚度與節(jié)段性RS、CS的相關(guān)性及整體RS、CS與LVEDV、LVESV、LVEF、LVMASS間的相關(guān)性。結(jié)果HCM組的LVMASS高于正常對照組[(133.74±79.13)g vs(76.87±14.15)g,P=0.01]。兩組間LVEDV、LVESV、LVEF差異均無統(tǒng)計學意義(P均0.05)。HCM組心肌整體RS、CS值均明顯低于正常對照組[RS:(27.05±13.35)%vs(40.62±4.92)%,P0.01;CS:(-8.68±5.56)%vs(-20.73±1.56)%,P0.01]。HCM患者各節(jié)段室壁厚度與節(jié)段性RS(r=-0.41,P0.01)、CS(r=0.28,P0.01)間無相關(guān)性;心肌整體RS(r=-0.36、-0.41、0.22、-0.36)、CS(r=0.34、0.10、0.22、0.42)與LVEDV、LVESV、LVEF、LVMASS間無相關(guān)性(P均0.05)。結(jié)論 CMR-FT有助于定量評估HCM患者心肌形變情況。
[Abstract]:Objective to evaluate the value of cardiac magnetic resonance (CMR) characteristic tracing (CMR-FT) in quantitative evaluation of myocardial deformation in patients with hypertrophic cardiomyopathy (HCM). Methods CMR was performed in 16 patients with HCM (HCM group) and 18 healthy volunteers (normal control group) with CMR-FT technique. The left ventricular end-diastolic volume (LVEDV),) end-systolic volume (LVESV), left ventricular ejection fraction (LVEF), left ventricular mass (LVEF),) and global radial strain (RS),) circumferential strain (CS) were compared between the two groups. The correlation between ventricular wall thickness and segmental RSV CS in patients with HCM and the correlation between whole RSV CS and LVMASS of LVESVV LVEFN were analyzed. Results the LVMASS of the HCM group was higher than that of the normal control group [(133.74 鹵79.13) g vs (76.87 鹵14.15) g P0. 01]. 涓ょ粍闂碙VEDV,LVESV,LVEF宸紓鍧囨棤緇熻瀛︽剰涔，

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