脊髓背角Ⅰ-Ⅲ層疼痛神經(jīng)環(huán)路的研究進(jìn)展
發(fā)布時間:2018-08-04 18:06
【摘要】:正脊髓背角是痛信息傳遞的關(guān)鍵門戶。大量研究結(jié)果證明,幾乎沒有來自于外周的痛信息僅在脊髓中繼就簡單地向上位腦結(jié)構(gòu)傳遞。目前能夠肯定的是,脊髓背角存在較為復(fù)雜的神經(jīng)環(huán)路,該環(huán)路的傳入是不同類型的初級傳入纖維,該環(huán)路內(nèi)部包括不同層次不同類型的神經(jīng)元,該環(huán)路的傳出較為單一,是投射神經(jīng)元,但是這些投射纖維不僅向傳統(tǒng)神經(jīng)解剖學(xué)概念上痛信息第三級神經(jīng)元丘腦投射,更多的投射纖維涉及其它多個腦區(qū)。同時,目前得到共識的是,脊髓背
[Abstract]:The dorsal horn of the spinal cord is a key gateway to the transmission of pain information. A large number of studies have demonstrated that almost no pain information from the periphery is transmitted simply up the brain structure in the spinal cord relay. At present, it is certain that there is a more complex neural loop in the dorsal horn of the spinal cord. The afferent fibers of this loop are different types of primary afferent fibers, and the inner part of the loop contains different layers and different types of neurons, and the efferent of the loop is relatively single. But these projective fibers not only project to the thalamus of the third-order neuronal pain information in the traditional neuroanatomical concept but also involve many other brain regions. At the same time, there is a consensus that the spinal dorsal
【作者單位】: 第四軍醫(yī)大學(xué)基礎(chǔ)部人體解剖與組織胚胎學(xué)教研室暨梁挾琚腦研究中心;烏魯木齊民族干部學(xué)院軍醫(yī)訓(xùn)練大隊學(xué)員一營;第四軍醫(yī)大學(xué)基礎(chǔ)部神經(jīng)生物學(xué)教研室;第四軍醫(yī)大學(xué)西京醫(yī)院肝膽外科;
【基金】:國家自然科學(xué)基金(81272555,81470843)
【分類號】:R402
,
本文編號:2164677
[Abstract]:The dorsal horn of the spinal cord is a key gateway to the transmission of pain information. A large number of studies have demonstrated that almost no pain information from the periphery is transmitted simply up the brain structure in the spinal cord relay. At present, it is certain that there is a more complex neural loop in the dorsal horn of the spinal cord. The afferent fibers of this loop are different types of primary afferent fibers, and the inner part of the loop contains different layers and different types of neurons, and the efferent of the loop is relatively single. But these projective fibers not only project to the thalamus of the third-order neuronal pain information in the traditional neuroanatomical concept but also involve many other brain regions. At the same time, there is a consensus that the spinal dorsal
【作者單位】: 第四軍醫(yī)大學(xué)基礎(chǔ)部人體解剖與組織胚胎學(xué)教研室暨梁挾琚腦研究中心;烏魯木齊民族干部學(xué)院軍醫(yī)訓(xùn)練大隊學(xué)員一營;第四軍醫(yī)大學(xué)基礎(chǔ)部神經(jīng)生物學(xué)教研室;第四軍醫(yī)大學(xué)西京醫(yī)院肝膽外科;
【基金】:國家自然科學(xué)基金(81272555,81470843)
【分類號】:R402
,
本文編號:2164677
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