【摘要】：目的研究產(chǎn)前篩查B族鏈球菌(GBS)方法的建立及其對母嬰感染防控作用。方法選取2013年12月至2015年1月西藏軍區(qū)總醫(yī)院進行產(chǎn)前體檢的孕婦1 000例,進行陰道口1、3及肛周拭子,做GBS篩查。篩查后分為陽性和陰性兩組,根據(jù)孕婦意愿陽性攜帶者分GBS干預(yù)治療組(M組)與不干預(yù)治療組(N組),記錄兩組產(chǎn)后出血,死產(chǎn),產(chǎn)后10d有無發(fā)熱,產(chǎn)后住院3d內(nèi)每日最高體溫等情況,及新生兒出生體質(zhì)量、Apgar評分等內(nèi)容,隨訪新生兒產(chǎn)后7d內(nèi)有無發(fā)熱、肺炎、敗血癥、腦膜炎等癥狀。結(jié)果 M組的流產(chǎn)數(shù)、早產(chǎn)數(shù)、胎膜早破數(shù)、產(chǎn)褥感染數(shù)及胎兒窘迫數(shù),產(chǎn)后出血率、死產(chǎn)率,產(chǎn)后住院3d內(nèi)每日最高體溫(≥37.5℃)的比例及產(chǎn)后10d內(nèi)發(fā)熱數(shù)等指標(biāo)明顯低于N組(P0.05)。兩組新生兒體質(zhì)量均在正常范圍內(nèi),Apgar評分正常,而M組的產(chǎn)后1周內(nèi)發(fā)熱、肺炎、敗血癥、腦膜炎等癥狀的發(fā)生率均低于N組(P0.05)。結(jié)論產(chǎn)前GBS篩選可以顯著提高新生兒相關(guān)安全性指標(biāo)。
[Abstract]:Objective to study the establishment of prenatal screening method for group B streptococcus (GBS) and its effect on prevention and control of mother-to-child infection. Methods from December 2013 to January 2015, 1 000 pregnant women who underwent antenatal examination in the General Hospital of Tibet military region were selected for GBS screening. After screening, positive and negative carriers were divided into two groups: GBS intervention group (group M) and non-intervention group (group N). Postpartum hemorrhage, stillbirth and fever were recorded in both groups. After 3 days of postpartum hospitalization, the highest body temperature and neonatal birth weight Apgar score were observed. There were no symptoms such as fever, pneumonia, septicemia, meningitis and so on. Results in group M, the number of abortion, premature delivery, premature rupture of membranes, puerperal infection and fetal distress, postpartum hemorrhage rate, stillbirth rate, The ratio of daily maximum body temperature (鈮，

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