血栓彈力圖在創(chuàng)傷性凝血病中的應(yīng)用
發(fā)布時(shí)間:2018-07-10 08:22
本文選題:血栓彈力圖 + 創(chuàng)傷性凝血病; 參考:《生物醫(yī)學(xué)工程與臨床》2017年03期
【摘要】:創(chuàng)傷導(dǎo)致約30%患者在入院時(shí)已并發(fā)凝血功能障礙。凝血功能障礙篩選試驗(yàn)在嚴(yán)重創(chuàng)傷出血患者中很難預(yù)測(cè)出血傾向,而血栓彈力圖(TEG)可以顯示從血凝塊開始形成到溶解時(shí)所有階段的變化。其優(yōu)勢(shì)是可快速識(shí)別纖溶亢進(jìn)。文章就TEG工作原理、優(yōu)缺點(diǎn)及其在創(chuàng)傷性凝血病患者中臨床應(yīng)用進(jìn)行闡述。TEG在創(chuàng)傷患者中的應(yīng)用有助于早期預(yù)測(cè)輸血、指導(dǎo)大量輸血復(fù)蘇、有助于評(píng)估創(chuàng)傷患者預(yù)后、聯(lián)合血小板圖鑒別診斷創(chuàng)傷前是否應(yīng)用抗血小板藥物造成的血小板功能的下降、區(qū)分機(jī)械性出血、加強(qiáng)重組活性凝血因子Ⅶ(rFⅦa)的管理,同時(shí)也對(duì)是否、何時(shí)使用抗纖溶藥物等提供依據(jù)。
[Abstract]:Trauma resulted in about 30% of patients with coagulation dysfunction at admission. Screening tests for coagulation dysfunction are difficult to predict bleeding tendency in patients with severe traumatic hemorrhage, while thromboelastography (TEG) can show changes in all stages from the beginning of clot formation to dissolution. Its advantage is that it can quickly identify hyperfibrinolysis. In this paper, the working principle, advantages and disadvantages of TEG and its clinical application in patients with traumatic coagulation disease are discussed. The application of TEG in trauma patients is helpful for early prediction of blood transfusion, guidance of blood transfusion resuscitation and evaluation of prognosis of trauma patients. In combination with thrombography, the differential diagnosis of platelet dysfunction caused by antiplatelet drugs before trauma, the differentiation of mechanical hemorrhage, the enhancement of the management of recombinant active coagulation factor 鈪,
本文編號(hào):2112805
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