血必凈注射液在毛細(xì)血管滲漏綜合征治療中的臨床研究
發(fā)布時(shí)間:2018-07-01 15:43
本文選題:血必凈 + 毛細(xì)血管滲漏綜合征 ; 參考:《國際檢驗(yàn)醫(yī)學(xué)雜志》2017年07期
【摘要】:目的研究分析血必凈注射液在治療毛細(xì)血管滲漏綜合征的臨床運(yùn)用效果。方法選擇2013年1月至2016年4月在該院治療的毛細(xì)血管滲漏綜合征患者100例,按照入院ID號隨機(jī)分為對照組與觀察組,兩組患者均給予毛細(xì)血管滲漏綜合征西醫(yī)常規(guī)治療。觀察組同時(shí)給予血必凈注射液治療。比較兩組治療前后APACHEⅡ、Mashall評分及血流動(dòng)力學(xué),動(dòng)態(tài)觀察患者病情變化。結(jié)果觀察組治療前后APACHEⅡ、Mashall評分明顯優(yōu)于對照組(P0.05);兩組患者在入院時(shí)外周血循環(huán)內(nèi)皮細(xì)胞(CEC)數(shù)量均高于正常水準(zhǔn),在采取治療后患者的CEC含量逐漸下降(P0.05),但觀察組CEC含量減少明顯優(yōu)于對照組(P0.01);觀察組在血管內(nèi)皮生長因子(VEGF)的表達(dá)及TNF-α、IL-6兩種細(xì)胞因子的表達(dá)優(yōu)于對照組(P0.05)。結(jié)論在毛細(xì)血管滲漏綜合征運(yùn)用血必凈注射液治療能夠有效保護(hù)患者血管內(nèi)皮細(xì)胞,提高患者生活質(zhì)量,可在臨床治療中推廣應(yīng)用。
[Abstract]:Objective to study the clinical effect of Xuebijing injection in the treatment of capillary leakage syndrome. Methods 100 patients with capillary leakage syndrome treated in our hospital from January 2013 to April 2016 were randomly divided into control group and observation group according to the number of admission ID. Both groups were given routine western medicine treatment for capillary leakage syndrome. The observation group was treated with Xuebijing injection at the same time. The score and hemodynamics of Apache 鈪,
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