發(fā)布時(shí)間：2018-06-28 18:36

  本文選題：輸血不良反應(yīng) + 相關(guān)因素　； 參考：《中國輸血雜志》2017年10期

【摘要】：目的分析臨床輸血不良反應(yīng)的發(fā)生特點(diǎn),尋找相關(guān)危險(xiǎn)因素,探討降低輸血不良反應(yīng)的預(yù)防措施。方法回顧性分析復(fù)旦大學(xué)附屬婦產(chǎn)科醫(yī)院及上海中醫(yī)藥大學(xué)附屬上海市中西醫(yī)結(jié)合醫(yī)院2014年1月-2017年1月內(nèi)接受輸血治療的1 058例病例資料,其中包括120例發(fā)生輸血不良反應(yīng)患者;分析常見輸血不良反應(yīng)發(fā)生率及原因,運(yùn)用單因素及多因素Logistic回歸分析輸血不良反應(yīng)發(fā)生相關(guān)的危險(xiǎn)因素。結(jié)果常見輸血不良反應(yīng)發(fā)生率約11.3%(過敏反應(yīng)約5.1%,發(fā)熱反應(yīng)約6.2%);血漿與冷沉淀引起的輸血不良反應(yīng)達(dá)到70%以上,去白細(xì)胞懸浮紅細(xì)胞最少;過敏反應(yīng)、發(fā)熱反應(yīng)所占的病例分別為45%(54/120)、55%(66/120);觀察組與對照組在輸血次數(shù)、發(fā)血至開始輸血時(shí)間間隔、輸血類型均存在差異(χ2=40.110,P0.001;χ2=137.924,P0.001;χ2=289.318,P0.001);多因素Logistic回歸分析顯示輸血次數(shù)、輸血類型、發(fā)血至開始輸血間隔為輸血不良反應(yīng)獨(dú)立預(yù)測因子(P0.05)。結(jié)論輸血不良反應(yīng)的主要危險(xiǎn)因素為輸血次數(shù)、輸血類型、血庫發(fā)血到開始輸血的時(shí)間間隔,因此臨床輸血應(yīng)嚴(yán)格掌握適應(yīng)證,合理選擇血液制品,降低輸血不良反應(yīng)的發(fā)生。
[Abstract]:Objective to analyze the characteristics of adverse reactions of blood transfusion, to find out the related risk factors and to explore the preventive measures to reduce the adverse reactions of blood transfusion. Methods the data of 1 058 cases who received blood transfusion treatment from January 2014 to January 2017 were retrospectively analyzed in Fudan University Obstetrics and Gynecology Hospital and Shanghai University of traditional Chinese Medicine affiliated Shanghai Integrated Chinese and Western Medicine Hospital from January 2014 to January 2017. The incidence and causes of common adverse reactions of blood transfusion were analyzed and the risk factors related to adverse reactions of blood transfusion were analyzed by univariate and multivariate logistic regression analysis. Results the incidence rate of common transfusion adverse reactions was about 11.3% (allergic reaction about 5.1%, fever reaction about 6.2%), the adverse reaction of blood transfusion caused by plasma and cryoprecipitation was more than 70%, leucocytic leucopenia erythrocyte was the least, allergic reaction was the lowest. Febrile reaction accounted for 45% (54 / 120) and 55% (66 / 120), respectively. There were significant differences between the observation group and the control group in the number of blood transfusions, the interval between the blood transfusion and the beginning of blood transfusion (蠂 2 / 40.110 / P 0.001; 蠂 ~ 2137.924 / P 0.001; 蠂 ~ 2 / 289.318P0.001); multivariate logistic regression analysis showed that the number of blood transfusions, the types of blood transfusions, and the types of blood transfusions were significantly different between the two groups. The interval from the onset of blood transfusion to the beginning of blood transfusion was an independent predictor of adverse reactions of blood transfusion (P0.05). Conclusion the main risk factors of adverse reaction of blood transfusion are the times of transfusion, the type of blood transfusion, the interval between blood transfusion and blood transfusion. Therefore, the indication of clinical transfusion should be strictly grasped, the blood products should be selected reasonably, and the occurrence of adverse reaction of blood transfusion should be reduced.
【作者單位】： 上海復(fù)旦大學(xué)附屬婦產(chǎn)科醫(yī)院;上海中醫(yī)藥大學(xué)附屬上海市中西醫(yī)結(jié)合醫(yī)院;
【分類號】：R457.13
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本文編號：2078959